{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T16:46:50Z","timestamp":1753894010316,"version":"3.41.2"},"reference-count":16,"publisher":"SLACK, Inc.","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Orthopedics"],"published-print":{"date-parts":[[2011,4,11]]},"abstract":"<jats:p>\n            Neuropathic arthropathy, or Charcot\u2019s joint, is a degenerative disorder resulting from abnormal sensory innervation that is associated with diabetes mellitus, tabes dorsalis, and syringomyelia. Patients may present with a painless instability of the affected joint, although a range of symptoms are seen. This article presents a case of a patient who presented with a swollen elbow, consistent with septic arthritis, and bilateral lower extremity weakness. Joint fluid cultures were positive for methicillin-resistant\n            <jats:italic>Staphylococcus aureus<\/jats:italic>\n            . Extensive joint destruction on radiographic imaging and a thorough neurologic examination revealing generalized weakness and upper motor neuron signs prompted magnetic resonance imaging (MRI) of the spine which revealed a cervical syrinx. Our patient was diagnosed with syringomyelia-associated neuropathic arthropathy that initially presented as a septic joint. In the setting of septic arthritis, substantial joint destruction (particularly in a patient with neurologic deficits) should prompt additional investigation, including MRI of the spine, for neurologic causes. Although surgery is generally not recommended for neuropathic arthropathy because of poor healing and high rates of complication, neuropathic arthropathy in the setting of a septic joint requires operative irrigation and debridement.\n          <\/jats:p>","DOI":"10.3928\/01477447-20110228-22","type":"journal-article","created":{"date-parts":[[2013,2,14]],"date-time":"2013-02-14T16:59:26Z","timestamp":1360861166000},"source":"Crossref","is-referenced-by-count":3,"title":["Septic Elbow in the Setting of Neuropathic Joint as the Initial Presentation of a Cervical Syrinx"],"prefix":"10.3928","volume":"34","author":[{"given":"Sophia A.","family":"Strike","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"James C.","family":"Johnston","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Payam","family":"Farjoodi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2308","reference":[{"key":"e_1_3_1_2_2","doi-asserted-by":"publisher","DOI":"10.5435\/00124635-199603000-00005"},{"key":"e_1_3_1_3_2","doi-asserted-by":"publisher","DOI":"10.2106\/00004623-196749010-00001"},{"issue":"3","key":"e_1_3_1_4_2","first-page":"194","article-title":"Char-cot\u2019s elbow (a case report)","volume":"27","author":"Bhaskaran RR","year":"1981","unstructured":"Bhaskaran RR, Suresh KK, Iyer GV. Char-cot\u2019s elbow (a case report). J Postgrad Med. 1981; 27(3):194\u2013196.","journal-title":"J Postgrad Med"},{"key":"e_1_3_1_5_2","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.139.2.7220879"},{"key":"e_1_3_1_6_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10067-005-0102-4"},{"key":"e_1_3_1_7_2","doi-asserted-by":"publisher","DOI":"10.2106\/00004623-200106000-00004"},{"issue":"3","key":"e_1_3_1_8_2","first-page":"54","article-title":"Neuropathic arthropathy caused by syringomyelia in different joints and lesion of brachial plexus at right upper extremity: a case report","volume":"19","author":"Ekim A","year":"2007","unstructured":"Ekim A, Arma\u011fan O. Neuropathic arthropathy caused by syringomyelia in different joints and lesion of brachial plexus at right upper extremity: a case report. Agri. 2007; 19(3):54\u201359.","journal-title":"Agri"},{"key":"e_1_3_1_9_2","doi-asserted-by":"publisher","DOI":"10.2106\/00004623-199809000-00010"},{"issue":"180","key":"e_1_3_1_10_2","first-page":"182","article-title":"Diagnosis of post-traumatic syringohydromyelia presenting as neuropathic joints. Report of two cases and review of the literature","author":"Rhoades CE","year":"1983","unstructured":"Rhoades CE, Neff JR, Rengachary SS, et al. Diagnosis of post-traumatic syringohydromyelia presenting as neuropathic joints. Report of two cases and review of the literature. Clin Orthop Relat Res. 1983; (180):182\u2013187.","journal-title":"Clin Orthop Relat Res"},{"issue":"40","key":"e_1_3_1_11_2","first-page":"109","article-title":"Charcot joints","author":"Storey G","year":"1964","unstructured":"Storey G. Charcot joints. Br J Vener Dis. 1964; (40):109\u2013117.","journal-title":"Br J Vener Dis"},{"issue":"4","key":"e_1_3_1_12_2","first-page":"533","article-title":"Neuropathic arthropathy of the elbow: a report of two cases","volume":"89","author":"Unnanuntana A","year":"2006","unstructured":"Unnanuntana A, Waikakul S. Neuropathic arthropathy of the elbow: a report of two cases. J Med Assoc Thai. 2006; 89(4):533\u2013540.","journal-title":"J Med Assoc Thai"},{"key":"e_1_3_1_13_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.50.3.825"},{"issue":"1","key":"e_1_3_1_14_2","first-page":"29","article-title":"Neuropathic arthropathy of the shoulder (Charcot shoulder)","volume":"7","author":"Cullen AB","year":"2005","unstructured":"Cullen AB, Ofluoglu O, Donthineni R. Neuropathic arthropathy of the shoulder (Charcot shoulder). MedGenMed. 2005; 7(1):29.","journal-title":"MedGenMed"},{"issue":"7","key":"e_1_3_1_15_2","first-page":"663","article-title":"Neuropathic arthropathy secondary to atypical congenital indifference to pain","volume":"61","author":"Fitzgerald JAW","year":"1968","unstructured":"Fitzgerald JAW, Manning CW. Neuropathic arthropathy secondary to atypical congenital indifference to pain. Proc R Soc Med. 1968; 61(7):663\u2013664.","journal-title":"Proc R Soc Med"},{"key":"e_1_3_1_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jse.2005.08.019"},{"key":"e_1_3_1_17_2","doi-asserted-by":"crossref","first-page":"1056","DOI":"10.1016\/B978-1-4160-2902-1.50082-6","volume-title":"The Elbow and Its Disorders","author":"Butters KP","year":"2009","unstructured":"Butters KP, Morrey BF. Septic arthritis. In: , Morrey BF, Sanchez-Sotelo J, eds. The Elbow and Its Disorders. Philadelphia, PA: Saunders; 2009:1056\u20131061."}],"container-title":["Orthopedics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.slackinc.com\/doi\/resolver.asp?doi=10.3928\/01477447-20110228-22","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,3]],"date-time":"2023-05-03T06:22:51Z","timestamp":1683094971000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.healio.com\/doi\/10.3928\/01477447-20110228-22"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,4,11]]},"references-count":16,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2011,4,11]]}},"alternative-id":["10.3928\/01477447-20110228-22"],"URL":"https:\/\/doi.org\/10.3928\/01477447-20110228-22","relation":{},"ISSN":["0147-7447","1938-2367"],"issn-type":[{"type":"print","value":"0147-7447"},{"type":"electronic","value":"1938-2367"}],"subject":[],"published":{"date-parts":[[2011,4,11]]},"article-number":"01477447-20110228-22"}}