{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,3]],"date-time":"2026-11-03T11:15:03Z","timestamp":1793704503858,"version":"4.5.1"},"reference-count":25,"publisher":"SLACK, Inc.","issue":"10","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Orthopedics"],"published-print":{"date-parts":[[2011,10,5]]},"abstract":"<jats:p>\n            The authors performed a systematic review and meta-analysis to evaluate whether there is a beneficial clinical effect of total disk replacement compared with anterior cervical diskectomy and fusion for the treatment of single-level symptomatic cervical disk disease. A comprehensive literature search of multiple databases, including PubMed (1966\u20132011), Cochrane Controlled Trials Register (CENTRAL; issue 1, 2011), and Embase (1984\u20132011), was conducted to identify studies that met the inclusion criteria. Methodologic quality was assessed and relevant data were retrieved, and if appropriate, meta-analysis was performed. Eight randomized controlled trials were identified; six of the 8 reported 24-month follow-up results. At 24 months, total disk replacement was demonstrated to be more beneficial for patients compared with anterior cervical diskectomy and fusion for the following outcomes: overall success rate (odds ratio [OR], 1.79; 95% confidence interval [CI], 1.37\u20132.33;\n            <jats:italic>P<\/jats:italic>\n            &lt;.0001), overall reoperation rate (OR,.36; CI, .21\u2013.61;\n            <jats:italic>P<\/jats:italic>\n            =0), reoperation rate for revision (OR, .12; CI, .02 to .64;\n            <jats:italic>P<\/jats:italic>\n            =.01), and visual analog scale neck pain scores (standard mean differences [SMD], \u2212.48; CI, \u2212.91 to \u2212.05;\n            <jats:italic>P<\/jats:italic>\n            =.03). Other outcomes, including Neck Disability Index scores (SMD, \u2212.02; CI, \u2212.44 to .27;\n            <jats:italic>P<\/jats:italic>\n            =.67) and visual analog scale arm pain scores (SMD, \u2212.21; CI, \u2212.63 to .22;\n            <jats:italic>P<\/jats:italic>\n            =.34), demonstrated no differences between the 2 groups. For patients with single-level symptomatic cervical disk disease, total disk replacement was found to be more effective than anterior cervical diskectomy and fusion in the 2 outcomes of overall success rate and overall reoperation rate at 24 months. Long-term results also showed total disk replacement trended to be more effective than anterior cervical diskectomy and fusion in some aspects.\n          <\/jats:p>","DOI":"10.3928\/01477447-20110826-09","type":"journal-article","created":{"date-parts":[[2011,9,28]],"date-time":"2011-09-28T17:52:59Z","timestamp":1317232379000},"source":"Crossref","is-referenced-by-count":22,"title":["Systematic Review and Meta-analysis of Randomized Controlled Trials: Comparison of Total Disk Replacement With Anterior Cervical Decompression and Fusion"],"prefix":"10.3928","volume":"34","author":[{"given":"Lin","family":"Yu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yueming","family":"Song","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xi","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chaoliang","family":"Lv","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2308","reference":[{"key":"e_1_3_1_2_2","doi-asserted-by":"publisher","DOI":"10.2106\/00004623-199309000-00005"},{"key":"e_1_3_1_3_2","doi-asserted-by":"publisher","DOI":"10.3171\/spi.2005.2.5.0521"},{"issue":"2","key":"e_1_3_1_4_2","first-page":"229","article-title":"Anterior cervical plating enhances arthrodesis after discectomy and fusion with cortical allograft","volume":"50","author":"Kaiser MG","year":"2002","unstructured":"Kaiser MG, Haid RW, Subach BR, Barnes B, Rodts GE. Anterior cervical plating enhances arthrodesis after discectomy and fusion with cortical allograft. Neurosurgery. 2002; 50(2):229\u2013236.","journal-title":"Neurosurgery"},{"key":"e_1_3_1_5_2","doi-asserted-by":"publisher","DOI":"10.2531\/spinalsurg.16.207"},{"key":"e_1_3_1_6_2","doi-asserted-by":"publisher","DOI":"10.3171\/spi.2005.3.6.0417"},{"key":"e_1_3_1_7_2","doi-asserted-by":"publisher","DOI":"10.1097\/00007632-200406010-00022"},{"key":"e_1_3_1_8_2","doi-asserted-by":"publisher","DOI":"10.1097\/00007632-200211150-00003"},{"key":"e_1_3_1_9_2","doi-asserted-by":"publisher","DOI":"10.2106\/00004623-199904000-00009"},{"issue":"1","key":"e_1_3_1_10_2","first-page":"17","article-title":"Influence of an artificial cervical joint compared with fusion on adjacent-level motion in the treatment of degenerative cervical disc disease","volume":"96","author":"Wigfield C","year":"2002","unstructured":"Wigfield C, Gill S, Nelson R, Langdon I, Metcalf N, Robertson J. Influence of an artificial cervical joint compared with fusion on adjacent-level motion in the treatment of degenerative cervical disc disease. J Neurosurg. 2002; 96(1 suppl):17\u201321.","journal-title":"J Neurosurg"},{"key":"e_1_3_1_11_2","doi-asserted-by":"publisher","DOI":"10.1097\/00002517-199512000-00014"},{"key":"e_1_3_1_12_2","doi-asserted-by":"publisher","DOI":"10.1097\/00007632-200301150-00008"},{"issue":"1","key":"e_1_3_1_13_2","first-page":"18","article-title":"Physical and monetary costs associated with autogenous bone graft harvesting","volume":"32","author":"St John TA","year":"2003","unstructured":"St John TA, Vaccaro AR, Sah AP, et al. Physical and monetary costs associated with autogenous bone graft harvesting. 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Comparison of single-level cervical fusion and a metal-on-metal cervical disc replacement device. 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