{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T08:08:34Z","timestamp":1789978114996,"version":"4.0.1"},"reference-count":17,"publisher":"SLACK, Inc.","issue":"12","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Orthopedics"],"published-print":{"date-parts":[[2011,12,6]]},"abstract":"<jats:p>The treatment of bone metastases is frequently palliative, aiming to achieve satisfactory pain control and to prevent or treat pathological fractures. For lesions involving the femur, internal fixation frequently fails; therefore, prosthetic reconstruction may be the optimal choice for treatment. This article retrospectively reviews our experience with femoral bone metastases between 1999 and 2008.<\/jats:p>\n          <jats:p>\n            A series of 22 patients (14 men and 8 women; mean age, 61.8 years) with femoral bone metastases were treated with resection and modular megaprosthetic reconstruction. Bipolar hip prostheses were used in 19 patients, intercalary prostheses were used in 2 patients, and total knee replacement was used in 1 patient. Oncologic outcome was evaluated, and functional outcomes were obtained by the Musculoskeletal Tumor Society (MSTS) score, which assigns numerical values (0\u20135) for each of 5 parameters, excluding emotional status. A numerical score (maximum 25 points) and percent rating was calculated. Six-month survival was 86.4%, 1-year survival was 54.2%, and 2-year survival was 37.1%. Three patients were unable to ambulate due to acute paraplegia with spinal metastases at the perioperative period. Excluding these 3 patients, average MSTS score was 62.3%. The MSTS score in patients surviving &gt;12 months was 70.8% compared with a score of 46.4% in those living &lt;12 months (\n            <jats:italic>P<\/jats:italic>\n            &lt;.05). Complications included 2 dislocations.\n          <\/jats:p>\n          <jats:p>Megaprosthetic reconstruction provides for optimal treatment of femoral metastatic disease in patients with a prognosis of &gt;12 months with satisfactory functional outcomes based on lower complications.<\/jats:p>","DOI":"10.3928\/01477447-20111021-13","type":"journal-article","created":{"date-parts":[[2011,12,6]],"date-time":"2011-12-06T13:54:34Z","timestamp":1323179674000},"source":"Crossref","is-referenced-by-count":18,"title":["Modular Megaprosthesis in Metastatic Bone Disease of the Femur"],"prefix":"10.3928","volume":"34","author":[{"given":"Hiroyuki","family":"Hattori","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junya","family":"Mibe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kengo","family":"Yamamoto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2308","reference":[{"key":"e_1_3_1_2_2","doi-asserted-by":"publisher","DOI":"10.1302\/0301-620X.83B4.12202"},{"key":"e_1_3_1_3_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199808063390609"},{"key":"e_1_3_1_4_2","doi-asserted-by":"publisher","DOI":"10.1097\/00003086-199611000-00030"},{"key":"e_1_3_1_5_2","doi-asserted-by":"publisher","DOI":"10.1097\/00005131-200008000-00003"},{"key":"e_1_3_1_6_2","doi-asserted-by":"publisher","DOI":"10.3109\/17453679909000953"},{"key":"e_1_3_1_7_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00443814"},{"key":"e_1_3_1_8_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.blo.0000093849.72468.82"},{"key":"e_1_3_1_9_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00402-007-0464-y"},{"issue":"4","key":"e_1_3_1_10_2","first-page":"211","article-title":"Modular prostheses in metastatic bone disease of the proximal femur","volume":"54","author":"Camnasio F","year":"1996","unstructured":"Camnasio F, Ravasi F. Modular prostheses in metastatic bone disease of the proximal femur. Bull Hosp Jt Dis. 1996; 54(4):211\u2013214.","journal-title":"Bull Hosp Jt Dis"},{"issue":"1","key":"e_1_3_1_11_2","first-page":"13","article-title":"Endoprosthetic replacement for bony metastases","volume":"74","author":"Chan D","year":"1992","unstructured":"Chan D, Carter SR, Grimer RJ, Sneath RS. Endoprosthetic replacement for bony metastases. Ann R Coll Surg Engl. 1992; 74(1):13\u201318.","journal-title":"Ann R Coll Surg Engl"},{"key":"e_1_3_1_12_2","doi-asserted-by":"publisher","DOI":"10.1186\/1749-799X-3-50"},{"key":"e_1_3_1_13_2","doi-asserted-by":"publisher","DOI":"10.1155\/2007\/62151"},{"key":"e_1_3_1_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.arth.2006.11.016"},{"key":"e_1_3_1_15_2","doi-asserted-by":"publisher","DOI":"10.1302\/0301-620X.87B5.15185"},{"issue":"286","key":"e_1_3_1_16_2","first-page":"241","article-title":"A system for the functional evaluation of reconstructive procedures after surgical treatment of tumors of the musculoskeletal system","author":"Enneking WF","year":"1993","unstructured":"Enneking WF, Dunham W, Gebhardt MC, Malawar M, Pritchard DJ. A system for the functional evaluation of reconstructive procedures after surgical treatment of tumors of the musculoskeletal system. Clin Orthop Relat Res. 1993; (286):241\u2013246.","journal-title":"Clin Orthop Relat Res"},{"key":"e_1_3_1_17_2","doi-asserted-by":"publisher","DOI":"10.1302\/0301-620X.87B12.16629"},{"key":"e_1_3_1_18_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.blo.0000170721.07088.2e"}],"container-title":["Orthopedics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.slackinc.com\/doi\/resolver.asp?doi=10.3928\/01477447-20111021-13","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,2]],"date-time":"2023-05-02T17:22:46Z","timestamp":1683048166000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.healio.com\/doi\/10.3928\/01477447-20111021-13"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,12,6]]},"references-count":17,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2011,12,6]]}},"alternative-id":["10.3928\/01477447-20111021-13"],"URL":"https:\/\/doi.org\/10.3928\/01477447-20111021-13","relation":{},"ISSN":["0147-7447","1938-2367"],"issn-type":[{"value":"0147-7447","type":"print"},{"value":"1938-2367","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,12,6]]}}}