{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,27]],"date-time":"2025-09-27T21:51:12Z","timestamp":1759009872698},"reference-count":11,"publisher":"SLACK, Inc.","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Orthopedics"],"published-print":{"date-parts":[[2012,1]]},"abstract":"<jats:p>Necrotizing fasciitis is an orthopedic emergency. The ability to quickly and accurately diagnose this rapidly spreading disease can save a patient\u2019s life and limb. However, the diagnosis is complex because necrotizing fasciitis usually manifests as a less severe cellulitis or abscess while the majority of the damages rage beneath the surface of the skin. Although the diagnosis is not new, the potential causes and vectors continually change. This article reports a new source of necrotizing fasciitis in an intramuscular injection of \u201cbath salts,\u201d a rapidly emerging street drug that is legal in some states and evades authorities with its innocuous name.<\/jats:p>\n          <jats:p>The patient presented 2 days after injection of bath salts with extensive cellulitis extending to the mid portion of her upper arm. The cellulitis initially responded to broad-spectrum intravenous antibiotics, but rapidly deteriorated 48 hours later, leading to a forequarter amputation with radical mastectomy and chest wall debridement to obtain healthy tissue margins and control the disease. The patient made a full recovery after further minor debridements, negative pressure dressings, directed antibiotic therapy, and skin grafting.<\/jats:p>\n          <jats:p>The recent emerging popularity of this highly obtainable, injectable substance may lead to an increase in cases of necrotizing fasciitis. Orthopedic surgeons should be vigilant in diagnosing this process early and should perform an extensive debridement.<\/jats:p>","DOI":"10.3928\/01477447-20111122-36","type":"journal-article","created":{"date-parts":[[2012,1,9]],"date-time":"2012-01-09T20:29:35Z","timestamp":1326140975000},"source":"Crossref","is-referenced-by-count":21,"title":["Life-threatening Necrotizing Fasciitis Due to \u2018Bath Salts\u2019 Injection"],"prefix":"10.3928","volume":"35","author":[{"given":"Russell","family":"Russo","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Noah","family":"Marks","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katy","family":"Morris","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Heather","family":"King","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Angelle","family":"Gelvin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ronald","family":"Rooney","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2308","reference":[{"issue":"4","key":"e_1_3_2_2_2","first-page":"416","article-title":"Necrotizing fasciitis","volume":"18","author":"Wilson B","year":"1952","unstructured":"Wilson B. Necrotizing fasciitis. Am Surg. 1952; 18(4):416\u2013431.","journal-title":"Am Surg"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(94)91956-9"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.3109\/15563650.2011.590812"},{"key":"e_1_3_2_5_2","volume-title":"MDPV Report","author":"Psychonaut WebMapping Research Group","year":"2009","unstructured":"Psychonaut WebMapping Research Group. MDPV Report. London, UK: Institute of Psychiatry, King\u2019s College London; 2009."},{"issue":"19","key":"e_1_3_2_6_2","first-page":"624","article-title":"Emergency department visits after use of a drug sold as \u201cbath salts\u201d--Michigan, November 13, 2010\u2013March 31, 2011","volume":"60","author":"Centers for Disease Control and Prevention (CDC)","year":"2011","unstructured":"Centers for Disease Control and Prevention (CDC). Emergency department visits after use of a drug sold as \u201cbath salts\u201d--Michigan, November 13, 2010\u2013March 31, 2011. MMWR Morb Mortal Wkly Rep. 2011; 60(19):624\u2013627.","journal-title":"MMWR Morb Mortal Wkly Rep"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.2106\/JBJS.K.00125"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.133.8.812"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-199505000-00013"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0196-0644(05)82667-8"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0266-7681(97)80376-2"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1086\/320874"}],"container-title":["Orthopedics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.slackinc.com\/doi\/resolver.asp?doi=10.3928\/01477447-20111122-36","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,2]],"date-time":"2023-05-02T16:22:13Z","timestamp":1683044533000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.healio.com\/doi\/10.3928\/01477447-20111122-36"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,1]]},"references-count":11,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2012,1]]}},"alternative-id":["10.3928\/01477447-20111122-36"],"URL":"https:\/\/doi.org\/10.3928\/01477447-20111122-36","relation":{},"ISSN":["0147-7447","1938-2367"],"issn-type":[{"value":"0147-7447","type":"print"},{"value":"1938-2367","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,1]]}}}