{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,5,31]],"date-time":"2024-05-31T15:16:18Z","timestamp":1717168578793},"reference-count":17,"publisher":"SLACK, Inc.","issue":"9","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Orthopedics"],"published-print":{"date-parts":[[2012,9]]},"abstract":"<jats:p>\n            Lipoma is a common benign soft tissue tumor. This article describes a massive osteolipoma, an unusual lipoma that is fixed to the femoral periosteum. A 21-year-old man presented with a subcutaneous mass at the knee region, which had been present for more than 36 months, and a slight limitation of joint flexibility. On physical examination, a mass approximately 12\u00d76\u00d72 cm\n            <jats:sup>3<\/jats:sup>\n            in dimension was palpable beneath the skin at the knee proximal medial area when the knee was in flexion. The mass was ovoid, hard, nontender, well demarcated, large, subcutaneous, and relatively fixed to the femur. Medical imaging examination showed that the femur had a well-demarcated mass with a basement. No prominent body weight loss was noted. The excisional mass of 16\u00d712\u00d710 cm\n            <jats:sup>3<\/jats:sup>\n            was not well encapsulated by a thin, fibrous membrane and had an apparently osseous basal portion. Intraoperative rapid frozen section revealed that the tumor was derived from the adipose cells. The postoperative course was uneventful. The definitive pathologic diagnosis was intermuscular osteolipoma without evidence of malignancy. No recurrence was observed at 6-month follow-up.\n          <\/jats:p>\n          <jats:p>Osteolipoma with independent bone and an osseous basal portion is rare, especially in young adults. Osteolipoma has the same prognosis as simple lipoma, and surgical excision is the recommended treatment. To the authors\u2019 knowledge, such a massive osteolipoma has not been reported.<\/jats:p>","DOI":"10.3928\/01477447-20120822-35","type":"journal-article","created":{"date-parts":[[2012,9,6]],"date-time":"2012-09-06T16:52:35Z","timestamp":1346950355000},"source":"Crossref","is-referenced-by-count":4,"title":["Rare Massive Osteolipoma in the Upper Part of the Knee in a Young Adult"],"prefix":"10.3928","volume":"35","author":[{"given":"Shi","family":"Cheng","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Song-cen","family":"Lu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bin","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhen","family":"Xue","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hong-wei","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2308","reference":[{"key":"e_1_3_1_2_2","volume-title":"Soft Tissue Tumors","author":"Enzinger FM","year":"1995","unstructured":"Enzinger FM, Weiss SW. 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J Neurosurg. 2001; 94 (1 suppl):126\u2013128.","journal-title":"J Neurosurg"},{"key":"e_1_3_1_6_2","doi-asserted-by":"publisher","DOI":"10.1155\/2009\/143460"},{"key":"e_1_3_1_7_2","doi-asserted-by":"publisher","DOI":"10.4076\/1757-1626-2-8711"},{"key":"e_1_3_1_8_2","doi-asserted-by":"publisher","DOI":"10.1017\/S002221510010917X"},{"key":"e_1_3_1_9_2","doi-asserted-by":"publisher","DOI":"10.1259\/bjr\/38805072"},{"key":"e_1_3_1_10_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11914-012-0096-1"},{"key":"e_1_3_1_11_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00256-011-1241-0"},{"issue":"2","key":"e_1_3_1_12_2","first-page":"125","article-title":"The differences between adipose tissue derived stem cells and lipoma mesenchymal stem cells in characteristics","volume":"26","author":"Qian YW","year":"2010","unstructured":"Qian YW, Gao JH, Lu F, Zheng XD. The differences between adipose tissue derived stem cells and lipoma mesenchymal stem cells in characteristics. 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