{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,11]],"date-time":"2025-11-11T13:01:08Z","timestamp":1762866068652},"reference-count":23,"publisher":"SLACK, Inc.","issue":"12","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Orthopedics"],"published-print":{"date-parts":[[2012,12]]},"abstract":"<jats:p>To the authors\u2019 knowledge, few reports have been published in the English literature of using total knee arthroplasty and total hip arthroplasty for the treatment of hereditary multiple exostoses. This article describes 2 patients with hereditary multiple exostoses, 1 treated with total hip arthroplasty and 1 treated with total knee arthroplasty. Bony deformities make arthroplasty uniquely challenging in patients undergoing total hip or knee arthroplasty. An expanded metaphysis of the proximal femur, coxa valga deformity, and the presence of hardware from previous reconstructive surgeries can make total hip arthroplasty technically difficult. Substantial bony deformity of the distal femur, valgus deformity of the knee, and sizing issues that necessitate custom implants can make total knee arthroplasty difficult. The most common bony deformities in hereditary multiple exostoses are short stature, limb-length discrepancy, valgus deformity at the knee and ankle, and asymmetry of the pectoral and pelvic girdles. Most reported surgical treatments for patients with hereditary multiple exostoses focus on the pediatric population or the management of malignant transformation of exostoses. Studies that specifically address the conditions associated with knee deformities focus on extra-articular deformity correction rather than arthroplasty.<\/jats:p>\n          <jats:p>When arthroplasty is necessary in this patient population, an understanding of the commonly occurring deformities can help with preoperative planning and surgical management. All painful lesions must be evaluated for malignant transformation. Bone scans can be useful during workup. All specimens should be sent for pathologic evaluation. Such patients are challenging because of the distorted hip anatomy and valgus knee deformity. The current 2 cases illustrate specific challenges that can be anticipated and underscore key principles for arthroplasty in the management of hereditary multiple exostoses.<\/jats:p>","DOI":"10.3928\/01477447-20121120-29","type":"journal-article","created":{"date-parts":[[2012,12,5]],"date-time":"2012-12-05T22:59:42Z","timestamp":1354748382000},"source":"Crossref","is-referenced-by-count":13,"title":["Total Hip and Knee Arthroplasty in Patients With Hereditary Multiple Exostoses"],"prefix":"10.3928","volume":"35","author":[{"given":"Addisu","family":"Mesfin","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria S.","family":"Goddard","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yetsa A.","family":"Tuakli-Wosornu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Harpal S.","family":"Khanuja","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2308","reference":[{"key":"e_1_3_1_2_2","doi-asserted-by":"publisher","DOI":"10.5435\/00124635-200503000-00004"},{"key":"e_1_3_1_3_2","doi-asserted-by":"publisher","DOI":"10.1136\/jmg.28.4.262"},{"key":"e_1_3_1_4_2","doi-asserted-by":"publisher","DOI":"10.2106\/00004623-199407000-00005"},{"key":"e_1_3_1_5_2","doi-asserted-by":"publisher","DOI":"10.1097\/00003086-200208000-00008"},{"key":"e_1_3_1_6_2","doi-asserted-by":"publisher","DOI":"10.2106\/JBJS.I.00301"},{"issue":"313","key":"e_1_3_1_7_2","first-page":"194","article-title":"Knee deformities in multiple hereditary exostoses. A longitudinal radiographic study","author":"Nawata K","year":"1995","unstructured":"Nawata K, Teshima R, Minamizaki T, Yamamoto K. Knee deformities in multiple hereditary exostoses. A longitudinal radiographic study. Clin Orthop Relat Res. 1995; (313):194\u2013199.","journal-title":"Clin Orthop Relat Res"},{"key":"e_1_3_1_8_2","doi-asserted-by":"publisher","DOI":"10.1097\/BPO.0b013e3181847511"},{"key":"e_1_3_1_9_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11999-010-1516-0"},{"key":"e_1_3_1_10_2","doi-asserted-by":"publisher","DOI":"10.1177\/112070000901900316"},{"key":"e_1_3_1_11_2","doi-asserted-by":"publisher","DOI":"10.1302\/0301-620X.83B7.10779"},{"key":"e_1_3_1_12_2","doi-asserted-by":"publisher","DOI":"10.2106\/JBJS.F.01336"},{"key":"e_1_3_1_13_2","doi-asserted-by":"publisher","DOI":"10.1097\/01202412-200511000-00009"},{"key":"e_1_3_1_14_2","doi-asserted-by":"publisher","DOI":"10.1097\/01241398-200201000-00025"},{"issue":"239","key":"e_1_3_1_15_2","first-page":"222","article-title":"Multiple hereditary osteochondromata","author":"Peterson HA","year":"1989","unstructured":"Peterson HA. Multiple hereditary osteochondromata. Clin Orthop Relat Res. 1989; (239):222\u2013230.","journal-title":"Clin Orthop Relat Res."},{"issue":"6","key":"e_1_3_1_16_2","first-page":"748","article-title":"Manifestations and management of osteochondromas: a retrospective analysis of 382 patients","volume":"72","author":"Saglik Y","year":"2006","unstructured":"Saglik Y, Altay M, Unal VS, Basarir K, Yildiz Y. Manifestations and management of osteochondromas: a retrospective analysis of 382 patients. Acta Orthop Belg. 2006; 72(6):748\u2013755.","journal-title":"Acta Orthop Belg"},{"key":"e_1_3_1_17_2","doi-asserted-by":"publisher","DOI":"10.2106\/00004623-197961060-00003"},{"key":"e_1_3_1_18_2","doi-asserted-by":"publisher","DOI":"10.1302\/0301-620X.82B4.9894"},{"key":"e_1_3_1_19_2","doi-asserted-by":"publisher","DOI":"10.5435\/00124635-200511000-00005"},{"key":"e_1_3_1_20_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.arthro.2004.04.012"},{"key":"e_1_3_1_21_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.arth.2010.07.017"},{"key":"e_1_3_1_22_2","article-title":"A new navigation-based technique for lateral distalizing condylar osteotomy in patients undergoing total knee arthroplasty with fixed valgus deformity [published online ahead of print July 14, 2012]","author":"Strauch M","unstructured":"Strauch M, von Eisenhart Rothe R, Graichen H. A new navigation-based technique for lateral distalizing condylar osteotomy in patients undergoing total knee arthroplasty with fixed valgus deformity [published online ahead of print July 14, 2012]. Knee Surg Sports Traumatol Arthrosc.","journal-title":"Knee Surg Sports Traumatol Arthrosc"},{"key":"e_1_3_1_23_2","doi-asserted-by":"publisher","DOI":"10.1302\/0301-620X.90B11.20092"},{"key":"e_1_3_1_24_2","first-page":"273","article-title":"Digital templating in total hip arthroplasty","volume":"57","author":"Whiddon DR","year":"2008","unstructured":"Whiddon DR, Bono JV. Digital templating in total hip arthroplasty. Instr Course Lect. 2008; 57:273\u2013279.","journal-title":"Instr Course Lect"}],"container-title":["Orthopedics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.healio.com\/doiresolver?doi=10.3928\/01477447-20121120-29","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,3]],"date-time":"2023-05-03T11:46:43Z","timestamp":1683114403000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.healio.com\/doi\/10.3928\/01477447-20121120-29"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,12]]},"references-count":23,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2012,12]]}},"alternative-id":["10.3928\/01477447-20121120-29"],"URL":"https:\/\/doi.org\/10.3928\/01477447-20121120-29","relation":{},"ISSN":["0147-7447","1938-2367"],"issn-type":[{"value":"0147-7447","type":"print"},{"value":"1938-2367","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,12]]}}}