{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,23]],"date-time":"2026-04-23T04:54:26Z","timestamp":1776920066202,"version":"3.51.2"},"reference-count":25,"publisher":"SLACK, Inc.","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Orthopedics"],"published-print":{"date-parts":[[2013,1]]},"abstract":"<jats:p>Proximal hamstring injuries can be disabling, and several traditional conservative treatments, including physiotherapy and nonsteroidal anti-inflammatory drugs, have been inconsistent. Corticosteroid injections have demonstrated success but can adversely affect local tissues. Platelet-rich plasma (PRP) has emerged as a safe, effective treatment for several orthopedic pathologies. The authors propose a PRP injection at the muscle origin as a novel treatment for proximal hamstring injuries.<\/jats:p>\n          <jats:p>\n            A retrospective review yielded 15 patients with 17 proximal hamstring injuries. Twelve injuries failed traditional conservative treatment and were ultimately treated with a PRP injection at the hamstrings muscle origin. Five patients were treated with traditional conservative treatment alone. Analysis included pre- and posttreatment visual analog scale scores, Nirschl Phase Rating Scale scores, and return to sport. No significant difference existed between the groups\u2019 pretreatment visual analog scale scores (\n            <jats:italic>P<\/jats:italic>\n            =.28) and Nirschl Phase Rating Scale scores (\n            <jats:italic>P<\/jats:italic>\n            =.15) and their posttreatment visual analog scale scores (\n            <jats:italic>P<\/jats:italic>\n            =.38) and Nirschl Phase Rating Scale scores (\n            <jats:italic>P<\/jats:italic>\n            =.22). The PRP group demonstrated a reduction in visual analog scale scores (\n            <jats:italic>P<\/jats:italic>\n            &lt;.01) and Nirschl Phase Rating Scale scores (\n            <jats:italic>P<\/jats:italic>\n            &lt;.01), but the traditional conservative treatment group did not demonstrate the same reduction (\n            <jats:italic>P<\/jats:italic>\n            =.06 and .06, respectively). All athletes returned to their desired activity level with no major complications.\n          <\/jats:p>","DOI":"10.3928\/01477447-20121217-20","type":"journal-article","created":{"date-parts":[[2012,12,31]],"date-time":"2012-12-31T14:41:21Z","timestamp":1356964881000},"source":"Crossref","is-referenced-by-count":85,"title":["Platelet-rich Plasma as an Effective Treatment for Proximal Hamstring Injuries"],"prefix":"10.3928","volume":"36","author":[{"given":"Robert J.","family":"Wetzel","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ronak M.","family":"Patel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael A.","family":"Terry","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2308","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1136\/bjsm.2004.015719"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1007\/s12178-007-9018-8"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1177\/0363546510379324"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1136\/bjsm.2006.028191"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1097\/00042752-200201000-00004"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-0031-1273753"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1097\/00042752-200301000-00009"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1177\/03635465000280030301"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1177\/036354657600400103"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1177\/0363546508322905"},{"issue":"4","key":"e_1_3_2_12_2","first-page":"443","article-title":"Platelet enriched plasma for acute muscle injury","volume":"76","author":"Hamilton B","year":"2010","unstructured":"Hamilton B, Knez W, Eirale C, Chalabi H. Platelet enriched plasma for acute muscle injury. Acta Orthop Belg. 2010; 76(4):443\u2013448.","journal-title":"Acta Orthop Belg"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.5435\/00124635-200910000-00002"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0278-5919(03)00051-6"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0030-5898(20)32343-9"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1083-7515(02)00056-6"},{"key":"e_1_3_2_17_2","doi-asserted-by":"publisher","DOI":"10.1177\/0363546506294078"},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.1177\/0363546509332257"},{"key":"e_1_3_2_19_2","doi-asserted-by":"publisher","DOI":"10.3810\/psm.2011.09.1925"},{"key":"e_1_3_2_20_2","doi-asserted-by":"publisher","DOI":"10.1177\/0363546511413454"},{"key":"e_1_3_2_21_2","doi-asserted-by":"publisher","DOI":"10.1097\/PRS.0b013e3182450ac9"},{"key":"e_1_3_2_22_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-4725.2012.02394.x"},{"key":"e_1_3_2_23_2","doi-asserted-by":"publisher","DOI":"10.1249\/01.MSS.0000089344.44434.50"},{"key":"e_1_3_2_24_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00167-009-0762-8"},{"issue":"1","key":"e_1_3_2_25_2","first-page":"11","article-title":"Treatment of tendon and muscle using platelet-rich plasma","volume":"28","author":"Mishra A","year":"2009","unstructured":"Mishra A, Woodall J, Vieira A. Treatment of tendon and muscle using platelet-rich plasma. Clin J Sports Med. 2009; 28(1):11\u2013125.","journal-title":"Clin J Sports Med"},{"key":"e_1_3_2_26_2","doi-asserted-by":"publisher","DOI":"10.5435\/00124635-201007000-00007"}],"container-title":["Orthopedics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.healio.com\/doiresolver?doi=10.3928\/01477447-20121217-20","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,3]],"date-time":"2023-05-03T02:46:13Z","timestamp":1683081973000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.healio.com\/doi\/10.3928\/01477447-20121217-20"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,1]]},"references-count":25,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2013,1]]}},"alternative-id":["10.3928\/01477447-20121217-20"],"URL":"https:\/\/doi.org\/10.3928\/01477447-20121217-20","relation":{},"ISSN":["0147-7447","1938-2367"],"issn-type":[{"value":"0147-7447","type":"print"},{"value":"1938-2367","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,1]]}}}