{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,3]],"date-time":"2026-04-03T00:15:56Z","timestamp":1775175356298,"version":"3.50.1"},"reference-count":28,"publisher":"SLACK, Inc.","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Orthopedics"],"published-print":{"date-parts":[[2022,7]]},"abstract":"<jats:p>\n            In response to increasing rates of self-reported latex allergies, changes have been made to prevent anaphylaxis in the operating room, including the use of latex-free gloves. However, the impact of these changes on the risk of prosthetic joint infection (PJI) after arthroplasty is unclear. This study evaluated whether documented latex allergy is an independent risk factor for PJI and aseptic revision surgery after total hip arthroplasty (THA) and total knee arthroplasty (TKA). A retrospective matched cohort study was conducted with an administrative claims database. A total of 17,501 patients who underwent TKA and had documented latex allergy were matched 1:4 with 70,004 control subjects, and 8221 patients who underwent THA and had documented latex allergy were matched 1:4 with 32,884 control subjects. Multivariable logistic regression showed that patients who had TKA and had a latex allergy showed significantly higher risk of PJI at both 90 days (odds ratio [OR], 1.26) and 1 year (OR, 1.22) and significantly higher risk of aseptic revision TKA at 1 year (OR, 1.21) after surgery compared with control subjects. Patients who had THA and had a latex allergy had significantly higher risk of PJI at 1 year (OR, 1.19) compared with control subjects. Rates of aseptic revision THA were higher in the latex allergy cohort but statistically comparable (\n            <jats:italic>P<\/jats:italic>\n            &gt;.05). Latex allergy was associated with significantly increased risk of PJI and aseptic revision after TKA and significantly increased risk of PJI after THA. More work is needed to determine whether these risks can be mitigated or if latex allergy is an inherent, nonmodifiable risk factor requiring modification to typical arthroplasty pathways. [\n            <jats:italic>Orthopedics<\/jats:italic>\n            . 2022;45(4):244\u2013250.]\n          <\/jats:p>","DOI":"10.3928\/01477447-20220401-03","type":"journal-article","created":{"date-parts":[[2022,4,8]],"date-time":"2022-04-08T12:31:35Z","timestamp":1649421095000},"page":"244-250","source":"Crossref","is-referenced-by-count":1,"title":["Latex Allergy as an Independent Risk Factor for Prosthetic Joint Infection"],"prefix":"10.3928","volume":"45","author":[{"given":"William F.","family":"Sherman","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bailey J.","family":"Ross","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sione A.","family":"Ofa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas C.","family":"Dowd","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Olivia C.","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2308","reference":[{"key":"e_1_3_1_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.arth.2016.01.043"},{"key":"e_1_3_1_3_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.blo.0000229356.81749.11"},{"key":"e_1_3_1_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.arth.2013.07.024"},{"key":"e_1_3_1_5_2","doi-asserted-by":"publisher","DOI":"10.1177\/03946320110240S308"},{"key":"e_1_3_1_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1081-1206(10)61886-8"},{"issue":"3","key":"e_1_3_1_7_2","first-page":"245","article-title":"Latex allergy in hospital employees","volume":"72","author":"Yassin MS","year":"1994","unstructured":"Yassin MS, Lierl MB, Fischer TJ, O'Brien K, Cross J, Steinmetz C. Latex allergy in hospital employees. Ann Allergy. 1994;72(3):245\u2013249. PMID:8129217","journal-title":"Ann Allergy"},{"key":"e_1_3_1_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.arth.2008.10.014"},{"key":"e_1_3_1_9_2","doi-asserted-by":"publisher","DOI":"10.1054\/arth.2001.23507"},{"key":"e_1_3_1_10_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00402-010-1146-8"},{"key":"e_1_3_1_11_2","unstructured":"American Academy of Orthopaedic Surgeons. Clinical Practice Guideline and Evidence Report on the Diagnosis and Prevention of Periprosthetic Joint Infection. 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One-year total hip arthroplasty revision rates in the US: incidence and aetiology. Orthop Proc. 2018;100-B(suppl 13). https:\/\/online.boneandjoint.org.uk\/doi\/abs\/10.1302\/1358-992X.2018.13.065.","journal-title":"Orthop Proc"},{"key":"e_1_3_1_27_2","doi-asserted-by":"publisher","DOI":"10.2106\/00004623-200202000-00002"},{"key":"e_1_3_1_28_2","unstructured":"Centers for Medicare & Medicaid Services. Medicare fee-for-service Supplemental Improper Payment Data 2019. 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