{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T13:16:49Z","timestamp":1790083009054,"version":"4.0.1"},"reference-count":35,"publisher":"SLACK, Inc.","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Orthopedics"],"published-print":{"date-parts":[[2023,1]]},"abstract":"<jats:p>\n            Intra-articular injections prior to total hip arthroplasty (THA) have been associated with postoperative infections. The purpose of this study was to determine whether a temporal relationship exists between hip injections prior to THA and infection. Specifically, we asked (1) Do patients who receive hip injections within 3 months of THA have a higher incidence of prosthetic joint infections (PJIs) or surgical site infections (SSIs)? and (2) Do these patients incur higher 90-day costs? Patients with hip injections prior to THA were identified using a national database from 2010 to 2019. Three laterality-specific groups (injection 0 to 3 months, 3 to 6 months, and 6 to 12 months prior to THA)were compared with a matched cohort without prior injection (n=277,841). Primary outcomes included PJIs, SSIs, and costs. Patients who had injections within 3 months of THA had a higher incidence of PJIs at 90 days (5.1% vs 1.6%,\n            <jats:italic>P<\/jats:italic>\n            &lt;.01) and 1 year (6.8% vs 2.1%,\n            <jats:italic>P<\/jats:italic>\n            &lt;.01), when compared with the matched cohort. They also had a higher incidence of SSIs at 90 days (2.8% vs 1.2%,\n            <jats:italic>P<\/jats:italic>\n            &lt;.01) and 1 year (3.7% vs 1.7%,\n            <jats:italic>P<\/jats:italic>\n            &lt;.01). Mean costs were 13.7% higher in this injection cohort. Patients who had injections between 3 and 6 months prior to THA had higher incidence and odds of postoperative PJIs at 90 days (2.6% vs 1.6%,\n            <jats:italic>P<\/jats:italic>\n            &lt;.04), whereas those with injections beyond 6 months had no differences in PJIs (\n            <jats:italic>P<\/jats:italic>\n            \u2265.46). Patients who receive hip injections within 3 months of undergoing primary THA are at increased risk for postoperative PJIs, SSIs, and higher costs. This study reaffirms guidelines for when to perform THAs in these populations. [\n            <jats:italic>Orthopedics<\/jats:italic>\n            . 2023;46(1):19\u201326.]\n          <\/jats:p>","DOI":"10.3928\/01477447-20221003-05","type":"journal-article","created":{"date-parts":[[2022,10,7]],"date-time":"2022-10-07T20:04:24Z","timestamp":1665173064000},"page":"19-26","source":"Crossref","is-referenced-by-count":4,"title":["Intra-articular Hip Injections Prior to Total Hip Arthroplasty: Infection and Cost-Related Associations"],"prefix":"10.3928","volume":"46","author":[{"given":"Oliver C.","family":"Sax","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Scott J.","family":"Douglas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sahir S.","family":"Pervaiz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hytham S.","family":"Salem","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Austin","family":"Nabet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael A.","family":"Mont","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ronald E.","family":"Delanois","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2308","reference":[{"key":"e_1_3_1_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.joca.2005.09.007"},{"key":"e_1_3_1_3_2","doi-asserted-by":"publisher","DOI":"10.1002\/art.22739"},{"key":"e_1_3_1_4_2","doi-asserted-by":"publisher","DOI":"10.1136\/ard.2009.127183"},{"key":"e_1_3_1_5_2","doi-asserted-by":"publisher","DOI":"10.2106\/JBJS.17.01617"},{"key":"e_1_3_1_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.arth.2016.04.008"},{"key":"e_1_3_1_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.arth.2015.08.032"},{"key":"e_1_3_1_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.arth.2015.05.027"},{"key":"e_1_3_1_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.arthro.2017.06.037"},{"key":"e_1_3_1_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.arth.2020.09.024"},{"key":"e_1_3_1_11_2","doi-asserted-by":"publisher","DOI":"10.12659\/MSM.890750"},{"key":"e_1_3_1_12_2","doi-asserted-by":"publisher","DOI":"10.1302\/0301-620X.98B8.37420"},{"key":"e_1_3_1_13_2","doi-asserted-by":"publisher","DOI":"10.3390\/antibiotics10030330"},{"key":"e_1_3_1_14_2","unstructured":"American Academy of Orthopaedic Surgeons. 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