{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,9]],"date-time":"2026-04-09T21:10:50Z","timestamp":1775769050976,"version":"3.50.1"},"reference-count":13,"publisher":"SLACK, Inc.","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Pediatr Ophthalmol Strabismus"],"published-print":{"date-parts":[[2005,1]]},"abstract":"<jats:sec>\n            <jats:title>Purpose:<\/jats:title>\n            <jats:p>To describe the results of corneal transplants in infants and young children with congenital corneal disorders.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Methods:<\/jats:title>\n            <jats:p>The charts of 38 children who underwent corneal transplantation for congenital corneal opacities from 1988 to 1999 at the Hospital for Sick Children, Toronto, Ontario, were reviewed. Parameters reviewed included indication, age at diagnosis and surgery, graft size, graft clarity, repeat surgery, glaucoma pre- and post-surgery, visual acuity, and refraction.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Results:<\/jats:title>\n            <jats:p>Thirty-eight children (63 eyes) underwent 86 corneal transplants. The four most common indications for surgery included posterior polymorphous dystrophy, Peters anomaly, congenital glaucoma, and sclerocornea. Mean follow-up was 40.4\u00b130.2 months (range, 2\u2013111 months). Seventy-eight percent of the grafts were clear at the final follow-up visit. There were 23 repeat grafts in the entire group.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusions:<\/jats:title>\n            <jats:p>The overall success rate of graft clarity was 78% for children undergoing corneal transplantation for congenitally opaque corneas. Best results were achieved in patients with posterior polymorphous dystrophy, followed by patients with Peters anomaly. Sclerocornea and congenital glaucoma carried a 50% chance of success, with repeated transplants needed for many of the eyes.<\/jats:p>\n            <jats:p>\n              <jats:bold>\n                <jats:italic>J Pediatr Ophthalmol Strabismus<\/jats:italic>\n                2005;42:34\u201344.\n              <\/jats:bold>\n            <\/jats:p>\n          <\/jats:sec>","DOI":"10.3928\/01913913-20050101-05","type":"journal-article","created":{"date-parts":[[2020,3,18]],"date-time":"2020-03-18T18:11:05Z","timestamp":1584555065000},"page":"34-44","source":"Crossref","is-referenced-by-count":38,"title":["Corneal Transplants for the Treatment of Congenital Corneal Opacities"],"prefix":"10.3928","volume":"42","author":[{"given":"Adi","family":"Michaeli","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aryeh","family":"Markovich","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David S.","family":"Rootman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2308","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1159\/000304714"},{"key":"e_1_3_2_3_2","first-page":"206","article-title":"Corneal transplantation in infants, children and young adults: experience of the Toronto Hospital for Sick Children, 1979\u201388","volume":"26","author":"Erlich CM","year":"1991","unstructured":"Erlich CM, Rootman DS, Morin JD. Corneal transplantation in infants, children and young adults: experience of the Toronto Hospital for Sick Children, 1979\u201388. Can J Ophthalmol 1991; 26:206\u2013210.1889022","journal-title":"Can J Ophthalmol"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.81.12.1064"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.2.5701.108"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1080\/01621459.1958.10501452"},{"key":"e_1_3_2_7_2","volume-title":"The Statistical Analysis of Failure Time Data","author":"Kalbfleisch JD","year":"1980","unstructured":"Kalbfleisch JD, Prentice RI. The Statistical Analysis of Failure Time Data. New York, NY: John Wiley and Sons; 1980."},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9394(98)00435-8"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(97)30093-1"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(99)90175-6"},{"key":"e_1_3_2_11_2","first-page":"32","article-title":"Peters' anomaly: a review of 26 penetrating keratoplasties in infants","volume":"24","author":"Parmley VC","year":"1993","unstructured":"Parmley VC, Stonecipher KG, Rowsey JJ. Peters' anomaly: a review of 26 penetrating keratoplasties in infants. Ophthalmic Surg 1993;24:32\u201335.","journal-title":"Ophthalmic Surg"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1067\/mpa.2001.117568"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(90)32586-1"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.3928\/0191-3913-19930301-11"}],"container-title":["Journal of Pediatric Ophthalmology &amp; Strabismus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.healio.com\/doiresolver?doi=10.3928\/01913913-20050101-05","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,3]],"date-time":"2023-05-03T01:46:47Z","timestamp":1683078407000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.healio.com\/doi\/10.3928\/01913913-20050101-05"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,1]]},"references-count":13,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2005,1]]}},"alternative-id":["10.3928\/01913913-20050101-05"],"URL":"https:\/\/doi.org\/10.3928\/01913913-20050101-05","relation":{},"ISSN":["0191-3913","1938-2405"],"issn-type":[{"value":"0191-3913","type":"print"},{"value":"1938-2405","type":"electronic"}],"subject":[],"published":{"date-parts":[[2005,1]]}}}