{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,5,3]],"date-time":"2023-05-03T06:45:49Z","timestamp":1683096349635},"reference-count":13,"publisher":"SLACK, Inc.","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Pediatr Ophthalmol Strabismus"],"published-print":{"date-parts":[[2010,11]]},"abstract":"<jats:sec>\n            <jats:title>Purpose:<\/jats:title>\n            <jats:p>The long-term outcome and postoperative visual acuity in a single family with ectopia lentis secondary to Marfan syndrome is presented.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Methods:<\/jats:title>\n            <jats:p>Thirteen family members, ages ranging from 3 to 47 years, were evaluated from 2006 to 2008. Ten members were found to have primary or secondary visual problems secondary to ectopia lentis.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Results:<\/jats:title>\n            <jats:p>\n              Evaluation of 10 members with subluxated lenses in three generations showed that the leading cause of loss of vision (&lt; 20\/200) was amblyopia (n = 5), followed by surgical complications (n = 2) and retinal detachment (n = 1). Moderate amblyopia was observed in 8 additional eyes. Of those with long axial length (&gt; 25 mm, n = 10), visual acuity ranged from 20\/400 to 20\/70 and no eyes tested better than 20\/40. In eight eyes with an axial length of less than 25 mm, visual acuity ranged between counting fingers and 20\/30. In this group, 50% had a visual outcome of 20\/40 or better. Two eyes had no light perception and phthisis secondary to surgical complications. Of the 18 eyes in which axial length data were available, more eyes in the axial myopia group had unfavorable visual outcome (\n              <jats:italic>P<\/jats:italic>\n              = .04, Wilcoxon signed rank test).\n            <\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusion:<\/jats:title>\n            <jats:p>Amblyopia due to delayed surgical intervention was the leading cause of visual loss in three generations of this family. Axial high myopia was more frequent in deeply amblyopic family members.<\/jats:p>\n          <\/jats:sec>","DOI":"10.3928\/01913913-20100318-06","type":"journal-article","created":{"date-parts":[[2010,4,22]],"date-time":"2010-04-22T17:49:12Z","timestamp":1271958552000},"page":"373-378","source":"Crossref","is-referenced-by-count":0,"title":["Visual Outcome of Three Generations in a Turkish Family with Marfan Syndrome"],"prefix":"10.3928","volume":"47","author":[{"given":"Silay Canturk","family":"Ugurbas","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2308","reference":[{"key":"e_1_3_1_2_2","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1096-8628(19960424)62:4<417::AID-AJMG15>3.0.CO;2-R"},{"key":"e_1_3_1_3_2","first-page":"235","article-title":"Bilateral ametropic functional amblyopia in genetic ectopia lentis: its relation to the amount of subluxation, an indicator for early surgical management","volume":"17","author":"Romano PE","year":"2002","unstructured":"Romano PE, Kerr NC, Hope GM. Bilateral ametropic functional amblyopia in genetic ectopia lentis: its relation to the amount of subluxation, an indicator for early surgical management. Binocul Vis Strabismus Q. 2002;17:235\u2013241.","journal-title":"Binocul Vis Strabismus Q"},{"key":"e_1_3_1_4_2","first-page":"229","article-title":"Evaluation of surgical intervention in familial isolated simple ectopia lentis: younger v. older generations","volume":"17","author":"Galvin JA","year":"2002","unstructured":"Galvin JA, Baker JD, Bawle EV. Evaluation of surgical intervention in familial isolated simple ectopia lentis: younger v. older generations. 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