{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T14:13:52Z","timestamp":1790604832281,"version":"4.1.0"},"reference-count":17,"publisher":"SLACK, Inc.","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Pediatr Ophthalmol Strabismus"],"published-print":{"date-parts":[[2018,3]]},"abstract":"<jats:sec>\n            <jats:title>Purpose:<\/jats:title>\n            <jats:p>To study the clinical profile and presentation of children with unilateral cataract.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Methods:<\/jats:title>\n            <jats:p>In this hospital-based, observational, cross-sectional study, patients 15 years of age or younger who presented with unilateral cataract were recruited. Cases of cataract secondary to causes such as trauma or uveitis were excluded. Age at detection and presentation, distance from the treatment center, presenting complaints, cataract morphology, and biometry were noted for each case.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Results:<\/jats:title>\n            <jats:p>\n              A total of 76 patients were recruited. Most patients presented with complaints of leukocoria. Persistent fetal vasculature accounted for 27.6% of cases and was the most common identifiable cause of cataract in this study. Subsequently, patients were divided into two groups: no persistent fetal vasculature (control) and persistent fetal vasculature. A male predominance was noted in both groups. The mean age at detection was 27.58 \u00b1 37.02 and 6.17 \u00b1 8.42 months and the mean age at presentation was 55.613 \u00b1 45.21 and 14.83 \u00b1 17.75 months in the control and persistent fetal vasculature groups, respectively. In the persistent fetal vasculature group, a significant difference was noted in the axial length, keratometry, and corneal diameter between the affected and normal eyes (\n              <jats:italic>P<\/jats:italic>\n              = .027, .00176, and .0114, respectively). In the control group, this difference was observed only in keratometry readings (\n              <jats:italic>P<\/jats:italic>\n              = .0464). The mean distance traveled by patients to reach the treatment center was 211 km.\n            <\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusions:<\/jats:title>\n            <jats:p>Persistent fetal vasculature is an important and less identified cause of unilateral cataract. A significant delay is noted in the detection and presentation of unilateral cataract.<\/jats:p>\n            <jats:p>\n              <jats:bold>\n                [\n                <jats:italic>J Pediatr Ophthalmol Strabismus<\/jats:italic>\n                . 2018;55(2):107\u2013112.]\n              <\/jats:bold>\n            <\/jats:p>\n          <\/jats:sec>","DOI":"10.3928\/01913913-20170703-11","type":"journal-article","created":{"date-parts":[[2017,11,13]],"date-time":"2017-11-13T21:31:31Z","timestamp":1510608691000},"page":"107-112","source":"Crossref","is-referenced-by-count":8,"title":["Unilateral Congenital Cataract: Clinical Profile and Presentation"],"prefix":"10.3928","volume":"55","author":[{"given":"Sudarshan","family":"Khokhar","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cijin P.","family":"Jose","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ramanjit","family":"Sihota","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Neha","family":"Midha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2308","reference":[{"key":"e_1_3_1_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0886-3350(97)80040-5"},{"key":"e_1_3_1_3_2","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.2005.074146"},{"key":"e_1_3_1_4_2","first-page":"2108","article-title":"Congenital and infantile cataract in the United Kingdom: underlying or associated factors: British Congenital Cataract Interest Group","volume":"41","author":"Rahi JS","year":"2000","unstructured":"Rahi JS, Dezateux C. Congenital and infantile cataract in the United Kingdom: underlying or associated factors: British Congenital Cataract Interest Group. Invest Ophthalmol Vis Sci. 2000;41:2108\u20132114.","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"e_1_3_1_5_2","first-page":"187","article-title":"Congenital cataracts: its laterality and association with consanguinity","volume":"30","author":"Rana AM","year":"2014","unstructured":"Rana AM, Raza A, Akhter W. Congenital cataracts: its laterality and association with consanguinity. 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CLAO J. 1990;16:99\u2013102.","journal-title":"CLAO J"}],"container-title":["Journal of Pediatric Ophthalmology &amp; Strabismus"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.healio.com\/doiresolver?doi=10.3928\/01913913-20170703-11","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,3]],"date-time":"2023-05-03T02:30:59Z","timestamp":1683081059000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.healio.com\/doi\/10.3928\/01913913-20170703-11"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,3]]},"references-count":17,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2018,3]]}},"alternative-id":["10.3928\/01913913-20170703-11"],"URL":"https:\/\/doi.org\/10.3928\/01913913-20170703-11","relation":{},"ISSN":["0191-3913","1938-2405"],"issn-type":[{"value":"0191-3913","type":"print"},{"value":"1938-2405","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,3]]}}}