{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,28]],"date-time":"2026-07-28T02:15:06Z","timestamp":1785204906008,"version":"3.55.0"},"reference-count":7,"publisher":"SLACK, Inc.","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Pediatr Ophthalmol Strabismus"],"published-print":{"date-parts":[[2017,11]]},"abstract":"<jats:p>\n            The authors report a case of asymptomatic leukemic optic neuropathy as the first sign of acute lymphoblastic leukemia relapse in a 4-year-old boy. Routine ophthalmologic examination showed normal visual acuity and pupillary function in the presence of a tumoral mass covering the left optic disc. The mass resolved with preservation of vision after intrathecal chemotherapy. A routine ophthalmological examination is recommended for all patients with a history of acute lymphoblastic leukemia to exclude optic nerve involvement without systemic symptoms or signs. Vision can be preserved and radiation avoided by using targeted chemotherapy.\n            <jats:bold>\n              [\n              <jats:italic>J Pediatr Ophthalmol Strabismus<\/jats:italic>\n              . 2017;54:e60\u2013e62.]\n            <\/jats:bold>\n          <\/jats:p>","DOI":"10.3928\/01913913-20170907-01","type":"journal-article","created":{"date-parts":[[2017,10,9]],"date-time":"2017-10-09T15:51:32Z","timestamp":1507564292000},"source":"Crossref","is-referenced-by-count":11,"title":["Asymptomatic Leukemic Optic Nerve Infiltration as Presentation of Acute Lymphoblastic Leukemia Relapse"],"prefix":"10.3928","volume":"54","author":[{"given":"Jane","family":"Caty","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A. Paula","family":"Grigorian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Florin","family":"Grigorian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2308","reference":[{"key":"e_1_3_1_2_2","doi-asserted-by":"publisher","DOI":"10.1038\/sj.eye.6701308"},{"key":"e_1_3_1_3_2","doi-asserted-by":"publisher","DOI":"10.1038\/sj.eye.6700701"},{"key":"e_1_3_1_4_2","doi-asserted-by":"publisher","DOI":"10.4103\/0974-620X.71902"},{"key":"e_1_3_1_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9394(88)90013-X"},{"key":"e_1_3_1_6_2","first-page":"97","article-title":"Unilateral optic nerve leukemic infiltration with sudden vision loss heralding a systemic relapse of acute lymphoblastic leukemia [article in Chinese]","volume":"25","author":"Lin HF","year":"2005","unstructured":"Lin HF, Dai MS, Kao WY, Chao TY. Unilateral optic nerve leukemic infiltration with sudden vision loss heralding a systemic relapse of acute lymphoblastic leukemia [article in Chinese]. Journal of Medical Sciences (Taiwan). 2005;25:97\u2013100.","journal-title":"Journal of Medical Sciences (Taiwan)"},{"key":"e_1_3_1_7_2","doi-asserted-by":"publisher","DOI":"10.3109\/10428199309054745"},{"key":"e_1_3_1_8_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00247-003-1137-9"}],"container-title":["Journal of Pediatric Ophthalmology &amp; Strabismus"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.healio.com\/doiresolver?doi=10.3928\/01913913-20170907-01","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,2]],"date-time":"2023-05-02T23:18:06Z","timestamp":1683069486000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.healio.com\/doi\/10.3928\/01913913-20170907-01"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,11]]},"references-count":7,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2017,11]]}},"alternative-id":["10.3928\/01913913-20170907-01"],"URL":"https:\/\/doi.org\/10.3928\/01913913-20170907-01","relation":{},"ISSN":["0191-3913","1938-2405"],"issn-type":[{"value":"0191-3913","type":"print"},{"value":"1938-2405","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,11]]}}}