{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,5,3]],"date-time":"2023-05-03T12:40:47Z","timestamp":1683117647139},"reference-count":10,"publisher":"SLACK, Inc.","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Psychosoc Nurs Ment Health Serv"],"published-print":{"date-parts":[[2012,1]]},"abstract":"<jats:p>\n            Acute agitation in patients with schizophrenia or bipolar disorder is an important clinical management problem. Liquid concentrates, orally disintegrating tablets, and\/or intramuscular formulations of several second-generation atypical antipsychotic drugs are available for treating acute agitation. Loxapine is an older first-generation antipsychotic drug that is approved for the treatment of schizophrenia. Staccato\n            <jats:sup>\u00ae<\/jats:sup>\n            loxapine is an investigational device system using a loxapine-coated heat source to administer loxapine by inhalation. Three multicenter, randomized, double-blind, placebo-controlled efficacy and safety studies of Staccato loxapine have been conducted in patients with acute agitation associated with schizophrenia or bipolar disorder. These studies found that inhaled loxapine was rapidly effective and generally well tolerated, although there are potential concerns about adverse pulmonary effects.\n          <\/jats:p>","DOI":"10.3928\/02793695-20111213-05","type":"journal-article","created":{"date-parts":[[2012,1,9]],"date-time":"2012-01-09T14:29:35Z","timestamp":1326119375000},"page":"16-18","source":"Crossref","is-referenced-by-count":1,"title":["Now Take a Deep Breath: Inhaled Loxapine for the Treatment of Acute Agitation"],"prefix":"10.3928","volume":"50","author":[{"given":"Robert H.","family":"Howland","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2308","reference":[{"key":"e_1_3_1_2_1","doi-asserted-by":"publisher","DOI":"10.4088\/JCP.10m06011yel"},{"key":"e_1_3_1_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1742-1241.2010.02615.x"},{"key":"e_1_3_1_4_1","first-page":"294","article-title":"Rapid tranquilization: A comparison of thiothixene with loxapine","volume":"47","author":"Dubin W.R.","year":"1986","unstructured":"Dubin W.R., Weiss K.J. (1986). Rapid tranquilization: A comparison of thiothixene with loxapine. Journal of Clinical Psychiatry, 47, 294\u2013297.","journal-title":"Journal of Clinical Psychiatry"},{"issue":"10","key":"e_1_3_1_5_1","first-page":"42","article-title":"Does loxapine have \u201catypical\u201d properties? Clinical evidence","volume":"60","author":"Glazer W.M.","year":"1999","unstructured":"Glazer W.M. (1999). Does loxapine have \u201catypical\u201d properties? Clinical evidence. Journal of Clinical Psychiatry, 60(Suppl. 10), 42\u201346.","journal-title":"Journal of Clinical Psychiatry"},{"key":"e_1_3_1_6_1","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.bp.110.081513"},{"key":"e_1_3_1_7_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrd2153"},{"key":"e_1_3_1_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/jps.20694"},{"key":"e_1_3_1_9_1","doi-asserted-by":"publisher","DOI":"10.1177\/0091270009347866"},{"key":"e_1_3_1_10_1","unstructured":"U.S. Food and Drug Administration. (2011a). December 12 2011: Psychopharmacologic Drugs Advisory Committee meeting announcement . Retrieved from http:\/\/www.fda.gov\/AdvisoryCommittees\/Calendar\/ucm277069.htm"},{"key":"e_1_3_1_11_1","unstructured":"U.S. Food and Drug Administration. (2011b). Memorandum: December 12 2011 Meeting of the Psychopharmacologic Drugs Advisory Committee . Retrieved from http:\/\/www.fda.gov\/downloads\/AdvisoryCommittees\/CommitteesMeetingMaterials\/Drugs\/PsychopharmacologicDrugsAdvisoryCommittee\/UCM282897.pdf"}],"container-title":["Journal of Psychosocial Nursing and Mental Health Services"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.slackinc.com\/doi\/resolver.asp?doi=10.3928\/02793695-20111213-05","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,3]],"date-time":"2023-05-03T12:02:56Z","timestamp":1683115376000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.healio.com\/doi\/10.3928\/02793695-20111213-05"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,1]]},"references-count":10,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2012,1]]}},"alternative-id":["10.3928\/02793695-20111213-05"],"URL":"https:\/\/doi.org\/10.3928\/02793695-20111213-05","relation":{},"ISSN":["0279-3695","1938-2413"],"issn-type":[{"value":"0279-3695","type":"print"},{"value":"1938-2413","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,1]]}}}