{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T05:25:42Z","timestamp":1787030742791,"version":"build-2736575974"},"reference-count":10,"publisher":"SLACK, Inc.","issue":"11","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Refract Surg"],"published-print":{"date-parts":[[2012,11]]},"abstract":"<jats:sec>\n                    <jats:title>PURPOSE:<\/jats:title>\n                    <jats:p>To report results of a series of highly aberrated corneas treated with a topography-guided excimer laser ablation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>METHODS:<\/jats:title>\n                    <jats:p>Retrospective, nonrandomized, consecutive series of eyes treated with topography-guided photorefractive keratectomy (TG-PRK) with the customized topographical neutralization technique (TNT). Cases included postoperative refractive surgery decentered ablations, optical zone enlargement, asymmetrical astigmatism, postoperative radial keratotomy (RK), postoperative keratoplasty, keratoconus combined with collagen cross-linking (CXL), and postoperative LASIK ectasia combined with CXL. Uncorrected distance visual acuity (UDVA), corrected distance visual acuity (CDVA), and manifest refraction were analyzed preoperatively and 6 months postoperatively.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS:<\/jats:title>\n                    <jats:p>In decentered ablation cases, 94% of 37 eyes were within 1.00 diopter (D) of the attempted refractive outcome, with 76% within 0.50 D. Mean topographic, central, optical zone of uniform (monodioptric) power increased from 3.5 to 5.2 mm in 25 eyes. Thirty-one eyes treated for asymmetrical astigmatism showed improvement in cylinder from mean 1.31 to 0.52 D. Ten of 11 eyes treated for previous RK astigmatism achieved postoperative UDVA 20\/40 or better. Twenty-seven eyes with postoperative keratoplasty astigmatism were treated, with 7 (25.9%) eyes gaining \u2a7e2 lines and 12 (44.4%) eyes gaining \u2a7e1 line of CDVA. Of eyes with keratoconus that were treated using TG-PRK with CXL, 42 (58%) eyes had UDVA 20\/40 or better, and 66 (92%) eyes had CDVA 20\/40 or better. Twelve (71%) of 17 eyes treated for postoperative LASIK ectasia using TG-PRK with CXL had UDVA 20\/40 or better. Nine (53%) eyes gained \u2a7e2 lines of CDVA.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSIONS:<\/jats:title>\n                    <jats:p>Topography-guided laser treatment with custom TNT, combined with CXL in keratoconus and ectasia, is an effective, safe, and increasingly predictable option for highly aberrated corneas.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3928\/1081597x-20121005-06","type":"journal-article","created":{"date-parts":[[2012,11,8]],"date-time":"2012-11-08T16:30:16Z","timestamp":1352392216000},"source":"Crossref","is-referenced-by-count":53,"title":["Clinical Results of Topography-based Customized Ablations in Highly Aberrated Eyes and Keratoconus\/Ectasia With Cross-linking"],"prefix":"10.3928","volume":"28","author":[{"given":"David T.C.","family":"Lin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simon","family":"Holland","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johnson C.H.","family":"Tan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gregory","family":"Moloney","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2308","reference":[{"issue":"4","key":"e_1_3_2_2_2","first-page":"S439","article-title":"Method for optimizing topography-guided ablation of highly aberrated eyes with the ALLEGRETTO WAVE excimer laser","volume":"24","author":"Lin DT","year":"2008","unstructured":"Lin DT, Holland S, Rocha KM, Krueger RR. Method for optimizing topography-guided ablation of highly aberrated eyes with the ALLEGRETTO WAVE excimer laser. J Refract Surg. 2008;24(4):S439\u2013S445.","journal-title":"J Refract Surg"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.3928\/1081-597X-20060401-03"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.3928\/1081597X-20100310-02"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.3928\/1081-597X-20050901-19"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1097\/ICU.0b013e328354adf0"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1097\/ICO.0b013e318074e424"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.3928\/1081597X-20090813-10"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.3928\/1081597X-20100121-10"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2011.04.033"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.3928\/1081597X-20101105-01"}],"container-title":["Journal of Refractive Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.healio.com\/doiresolver?doi=10.3928\/1081597X-20121005-06","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,2]],"date-time":"2023-05-02T23:45:47Z","timestamp":1683071147000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.healio.com\/doi\/10.3928\/1081597X-20121005-06"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,11]]},"references-count":10,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2012,11]]}},"alternative-id":["10.3928\/1081597X-20121005-06"],"URL":"https:\/\/doi.org\/10.3928\/1081597x-20121005-06","relation":{},"ISSN":["1081-597X"],"issn-type":[{"value":"1081-597X","type":"print"}],"subject":[],"published":{"date-parts":[[2012,11]]}}}