{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T07:31:08Z","timestamp":1791963068218,"version":"4.3.4"},"reference-count":15,"publisher":"SLACK, Inc.","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Refract Surg"],"published-print":{"date-parts":[[2013,1,1]]},"abstract":"<jats:sec>\n                    <jats:title>PURPOSE:<\/jats:title>\n                    <jats:p>To evaluate the safety and efficacy of intrastromal corneal ring segments (ICRS) implantation followed by same-day topography-guided photorefractive keratectomy (PRK) and ultraviolet-A\/riboflavin collagen cross-linking (CXL) in patients with low to moderate keratoconus.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>METHODS:<\/jats:title>\n                    <jats:p>Patients with low to moderate keratoconus and contact lens intolerance were included in the study. All patients first underwent femtosecond laser\u2013enabled placement of ICRS (Keraring, Mediphacos) (first step). Same-day topography-guided PRK and CXL (second step) were subsequently performed in all patients after the refraction was stable (average 6 months [range: 3 to 11 months]).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS:<\/jats:title>\n                    <jats:p>\n                      Thirteen eyes from 13 patients were included in the study. Based on values before the first step and 6 months after the second step, significant improvements were noted in uncorrected distance visual acuity (0.7\u00b10.32 logMAR vs 0.08\u00b10.08 logMAR), corrected distance visual acuity (CDVA) (0.16\u00b10.19 logMAR vs 0.02\u00b10.04 log-MAR), sphere (\u22123.65\u00b13.08 diopters [D] vs 0.06\u00b11.6 D), astigmatism (\u22123.31\u00b11.5 D vs \u22120.98\u00b10.75 D), average K (47.28\u00b11.99 D vs 41.42\u00b13.22 D), and coma (2.36\u00b11.23\n                      <jats:italic toggle=\"yes\">\u03bc<\/jats:italic>\n                      m vs 1.47\u00b10.68\n                      <jats:italic toggle=\"yes\">\u03bc<\/jats:italic>\n                      m) (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt;.05). Approximately 63% of eyes gained \u2a7e2 lines of CDVA, whereas no change in CDVA was reported in \u223c27% of eyes. No eyes lost lines of CDVA.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSIONS:<\/jats:title>\n                    <jats:p>The combination of ICRS implantation followed by sequential same-day topography-guided PRK\/CXL may be a reasonable option for improving visual acuity in patients with low to moderate keratoconus.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3928\/1081597x-20121228-04","type":"journal-article","created":{"date-parts":[[2013,1,11]],"date-time":"2013-01-11T10:34:51Z","timestamp":1357900491000},"page":"59-64","source":"Crossref","is-referenced-by-count":28,"title":["Intracorneal Ring Segments Implantation Followed by Same-day Topography-guided PRK and Corneal Collagen CXL in Low to Moderate Keratoconus"],"prefix":"10.3928","volume":"29","author":[{"given":"Waleed","family":"Al-Tuwairqi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mazen M.","family":"Sinjab","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2308","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrs.2007.12.039"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.3928\/1081597X-20100114-03"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.3109\/08820538.2010.518503"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1097\/ICO.0b013e318191b83d"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrs.2009.07.008"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrs.2010.06.044"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1097\/ICO.0b013e318074e424"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.3928\/1081597X-20101105-01"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.3928\/1081597X-20090813-09"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrs.2009.03.025"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2011.04.033"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.3928\/1081597X-20111103-03"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9394(02)02220-1"},{"issue":"4","key":"e_1_3_2_15_2","first-page":"S439","article-title":"Method for optimizing topography-guided ablation of highly aberrated eyes with the ALLEGRETTO WAVE excimer laser","volume":"24","author":"Lin DT","year":"2008","unstructured":"Lin DT, Holland SR, Rocha KM, Krueger RR. Method for optimizing topography-guided ablation of highly aberrated eyes with the ALLEGRETTO WAVE excimer laser. J Refract Surg. 2008;24(4):S439\u2013S445.","journal-title":"J Refract Surg"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.3928\/1081597X-20100121-10"}],"container-title":["Journal of Refractive Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.healio.com\/doiresolver?doi=10.3928\/1081597X-20121228-04","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,21]],"date-time":"2026-04-21T20:06:59Z","timestamp":1776802019000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.healio.com\/doi\/10.3928\/1081597X-20121228-04"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,1,1]]},"references-count":15,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2013,1,1]]}},"alternative-id":["10.3928\/1081597X-20121228-04"],"URL":"https:\/\/doi.org\/10.3928\/1081597x-20121228-04","relation":{},"ISSN":["1081-597X"],"issn-type":[{"value":"1081-597X","type":"print"}],"subject":[],"published":{"date-parts":[[2013,1,1]]}}}