{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,2]],"date-time":"2026-01-02T07:45:43Z","timestamp":1767339943759},"reference-count":28,"publisher":"SLACK, Inc.","issue":"9","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Refract Surg"],"published-print":{"date-parts":[[2015,9]]},"abstract":"<jats:sec>\n            <jats:title>PURPOSE:<\/jats:title>\n            <jats:p>To examine the microstructure of the cornea after excimer and femtosecond laser-assisted penetrating keratoplasty (ELAK and FLAK) in eyes with Fuchs\u2019 dystrophy and keratoconus.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>METHODS:<\/jats:title>\n            <jats:p>Fifty-seven patients were divided into four groups according to corneal disease and surgical technique: Fuchs\u2019 dystrophy and ELAK (n = 9; mean age: 70.4 \u00b1 10.6 years); Fuchs\u2019 dystrophy and FLAK (n = 13; mean age: 64.3 \u00b1 11.2 years); keratoconus and ELAK (n = 9; mean age: 47.4 \u00b1 13.9 years); and keratoconus and FLAK (n = 9; mean age: 43.5 \u00b1 13.8 years). The control group comprised individuals without ocular disease (n = 17; mean age: 39.9 \u00b1 17.3 years). In vivo investigation of the corneal graft and graft\u2013host junction zone was performed with confocal corneal microscopy.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>RESULTS:<\/jats:title>\n            <jats:p>\n              All corneal grafts were transparent and no rejection reaction could be observed during the follow-up period. Confocal microscopy revealed no difference in basal epithelial cell density compared to controls. Anterior keratocyte density was lower than in the control group (818 \u00b1 131 cells\/mm\n              <jats:sup>2<\/jats:sup>\n              ) in all four treatment groups (596 \u00b1 174, 586 \u00b1 113, 529 \u00b1 75, 552 \u00b1 91 cells\/mm\n              <jats:sup>2<\/jats:sup>\n              ). Langerhans cells could barely be seen; there was no difference in the cutting edge configuration and wound integrity.\n            <\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>CONCLUSIONS:<\/jats:title>\n            <jats:p>In vivo confocal microscopy provided evidence that good alignment of graft\u2013host junction could be created with both techniques. The excimer laser was not inferior to the femtosecond laser in performing corneal cuts. The low density of Langerhans cells revealed well-controlled cellular immunological response and sustained corneal integrity in both laser groups.<\/jats:p>\n            <jats:p>\n              <jats:bold>\n                [\n                <jats:italic>J Refract Surg.<\/jats:italic>\n                2015;31(9):620\u2013626.]\n              <\/jats:bold>\n            <\/jats:p>\n          <\/jats:sec>","DOI":"10.3928\/1081597x-20150820-08","type":"journal-article","created":{"date-parts":[[2015,9,9]],"date-time":"2015-09-09T14:13:03Z","timestamp":1441807983000},"page":"620-626","source":"Crossref","is-referenced-by-count":13,"title":["In Vivo Confocal Microscopic Imaging of the Cornea After Femtosecond and Excimer Laser-assisted Penetrating Keratoplasty"],"prefix":"10.3928","volume":"31","author":[{"given":"Mikl\u00f3s D.","family":"Resch","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elena","family":"Zemova","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L\u00e1szl\u00f3","family":"Marsovszky","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N\u00f3ra","family":"Szentm\u00e1ry","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Florian","family":"Bauer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Loay","family":"Daas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Max","family":"Pattm\u00f6ller","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Moatasem","family":"El-Husseiny","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J\u00e1nos","family":"N\u00e9meth","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zolt\u00e1n Z.","family":"Nagy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Berthold","family":"Seitz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2308","reference":[{"key":"e_1_3_2_2_2","first-page":"122","article-title":"Excimer laser 193 nm trephination with \u201corientation teeth\u201d in penetrating keratoplasty","volume":"99","author":"Naumann GO","year":"1992","unstructured":"Naumann GO, Seitz B. 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