{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T17:46:48Z","timestamp":1782236808378,"version":"3.54.5"},"reference-count":13,"publisher":"SLACK, Inc.","issue":"12","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Refract Surg"],"published-print":{"date-parts":[[2015,12,1]]},"abstract":"\n PURPOSE:<\/jats:title>\n To describe the big-bubble full femtosecond laser-assisted (BBFF) technique, which could be helpful in standardizing the big-bubble technique in deep anterior lamellar keratoplasty (DALK).<\/jats:p>\n <\/jats:sec>\n \n METHODS:<\/jats:title>\n \n Ten eyes of 10 consecutive patients affected by keratoconus underwent the BBFF technique using the 150-kHz IntraLase femtosecond laser (Intra-Lase FS Laser; Abbott Medical Optics, Inc., Santa Ana, CA). A 9-mm diameter metal mask with a single fissure 0.7 mm wide oriented at the 12-o'clock position was positioned into the cone, over the laser glass. The laser performed a ring lamellar cut (internal diameter = 3 mm; external diameter = 8 mm) 100\n \u00b5<\/jats:italic>\n m above the thinnest point, with the photodisruption effectively occurring only in the corneal stroma corresponding to the fissure to create a deep stromal channel; subsequently, an anterior side cut created an arcuate incision, from the corneal surface to the deep stromal channel on the mask's opening site. The mask was removed and the laser performed a full lamellar cut 200\n \u00b5<\/jats:italic>\n m above the thinnest point to create a lamella. After the removal of the lamella, the air needle was inserted into the stromal channel and air was injected to achieve a big bubble.\n <\/jats:p>\n <\/jats:sec>\n \n RESULTS:<\/jats:title>\n The big bubble was achieved in 9 eyes (all type 1 bubbles) and all procedures were completed as DALK.<\/jats:p>\n <\/jats:sec>\n \n CONCLUSIONS:<\/jats:title>\n Preliminary results suggest that the BBFF technique could help in standardizing the big-bubble technique in DALK, reducing the \u201clearning curve\u201d for surgeons who approach this technique and the risks of intraoperative complications.<\/jats:p>\n \n \n [\n J Refract Surg.<\/jats:italic>\n 2015;31(12):830\u2013834.]\n <\/jats:bold>\n <\/jats:p>\n <\/jats:sec>","DOI":"10.3928\/1081597x-20151111-07","type":"journal-article","created":{"date-parts":[[2015,12,10]],"date-time":"2015-12-10T08:07:40Z","timestamp":1449734860000},"page":"830-834","source":"Crossref","is-referenced-by-count":10,"title":["The Big-Bubble Full Femtosecond Laser-Assisted Technique in Deep Anterior Lamellar Keratoplasty"],"prefix":"10.3928","volume":"31","author":[{"given":"Luca","family":"Buzzonetti","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gianni","family":"Petrocelli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paola","family":"Valente","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giancarlo","family":"Iarossi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roberta","family":"Ardia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sergio","family":"Petroni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rosa","family":"Parrilla","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2308","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.3928\/1081-597X-19971101-12"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1097\/IIO.0b013e318272d44a"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1097\/ICO.0b013e318254a4e4"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrs.2009.01.012"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrs.2009.01.011"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1155\/2012\/264590"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9394(98)00067-1"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.81.3.184"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.83.3.327"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1097\/00003226-200205000-00009"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1097\/00055735-199908000-00006"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0886-3350(01)01181-6"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrs.2010.08.013"}],"container-title":["Journal of Refractive Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.healio.com\/doiresolver?doi=10.3928\/1081597X-20151111-07","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T16:52:03Z","timestamp":1782233523000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.healio.com\/doi\/10.3928\/1081597X-20151111-07"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,12,1]]},"references-count":13,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2015,12,1]]}},"alternative-id":["10.3928\/1081597X-20151111-07"],"URL":"https:\/\/doi.org\/10.3928\/1081597x-20151111-07","relation":{},"ISSN":["1081-597X"],"issn-type":[{"value":"1081-597X","type":"print"}],"subject":[],"published":{"date-parts":[[2015,12,1]]}}}