{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,19]],"date-time":"2026-03-19T12:20:19Z","timestamp":1773922819389,"version":"3.50.1"},"reference-count":41,"publisher":"SLACK, Inc.","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Ophthalmic Surg Lasers Imaging Retina"],"published-print":{"date-parts":[[2009,5]]},"abstract":"<jats:sec><jats:title>Background and Objective:<\/jats:title><jats:p>The authors evaluated the results of topical cyclosporin A 1% and injected mitomycin C 0.01% use as adjunctive therapy for prevention of primary pterygium recurrence.<\/jats:p><\/jats:sec><jats:sec><jats:title>Patients and Methods:<\/jats:title><jats:p>Eighty eyes of 76 consecutive patients who had pterygium excision surgery in a prospective, interventional clinical trial received conjunctival autografting combined with an immediate postoperative 0.1-cc injection of 0.01% mitomycin C in caruncula were randomized into two groups: those who received postoperative topical application of cyclosporin A and those who did not.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results:<\/jats:title><jats:p>The recurrence rate in patients who received topical application of postoperative cyclosporin A was 7.5% (3 of 40) compared with 17.5% (7 of 40) for patients who did not receive topical application of postoperative cyclosporin A (<jats:italic>P<\/jats:italic>= .31). An unexpected and significant finding in women was that those who received cyclosporin A had no recurrences (0 of 26), whereas those who did not receive cyclosporin A did (6 of 25; 24%) (<jats:italic>P<\/jats:italic>= .03).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion:<\/jats:title><jats:p>Intracaruncular mitomycin C 0.01% and topical cyclosporin A 1% combined with conjunctival autograft is useful in reducing pterygium recurrence.<\/jats:p><jats:p><jats:bold>[Ophthalmic Surg Lasers Imaging 2009;40:239\u2013244.]<\/jats:bold><\/jats:p><\/jats:sec>","DOI":"10.3928\/15428877-20090430-03","type":"journal-article","created":{"date-parts":[[2009,6,18]],"date-time":"2009-06-18T20:52:41Z","timestamp":1245358361000},"page":"239-244","source":"Crossref","is-referenced-by-count":12,"title":["Topical Cyclosporin A and Mitomycin C Injection as Adjunctive Therapy for Prevention of Primary Pterygium Recurrence"],"prefix":"10.3928","volume":"40","author":[{"given":"Miguel A.","family":"Ib\u00e1\u00f1ez","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marcela F.","family":"Eugarrios","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Delmy I.","family":"Calder\u00f3n","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2308","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.56.2.120"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(85)33831-9"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(89)32667-4"},{"key":"e_1_3_2_5_2","first-page":"9","article-title":"Cirug\u00eda de pterigion: membrana amniotica vs. autoinjerto conjunctival","volume":"80","author":"Ib\u00e1\u00f1ez MA","year":"2006","unstructured":"Ib\u00e1\u00f1ez MA, Ramos K. 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