{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T15:25:33Z","timestamp":1759332333834},"reference-count":17,"publisher":"SLACK, Inc.","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Ophthalmic Surg Lasers Imaging Retina"],"published-print":{"date-parts":[[2009,5]]},"abstract":"<jats:sec>\n            <jats:title>Background and Objective:<\/jats:title>\n            <jats:p>When corneal perforation develops in patients with severe ocular surface disease and limbal stem cell deficiency following childhood trachoma infection, penetrating keratoplasty is doomed to fail. To overcome this problem, the use of a fresh-tissue corneolimbal covering graft is described.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Patients and Methods:<\/jats:title>\n            <jats:p>Retrospective interventional case series of four patients who presented to a tertiary center from 2003 to 2005 with a large corneal perforation due to ocular surface disease. Emergency surgery consisted of suturing a fresh-tissue corneolimbal covering graft to the patients' peripheral sclera.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Results:<\/jats:title>\n            <jats:p>The corneolimbal graft became partially incorporated into the perforated cornea, which healed by scar tissue, after a few months. The ocular epithelial surface improved considerably. There was no recurrence of corneal perforation during the follow-up period of 1 to 3 years.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusion:<\/jats:title>\n            <jats:p>Fresh-tissue corneolimbal covering graft was found to be a useful technique for saving the integrity of the eye in cases of a large corneal perforation in patients with severe ocular surface disease, such as in childhood trachoma.<\/jats:p>\n            <jats:p>\n              <jats:bold>[Ophthalmic Surg Lasers Imaging 2009;40:245\u2013250.]<\/jats:bold>\n            <\/jats:p>\n          <\/jats:sec>","DOI":"10.3928\/15428877-20090430-04","type":"journal-article","created":{"date-parts":[[2009,6,18]],"date-time":"2009-06-18T20:52:30Z","timestamp":1245358350000},"page":"245-250","source":"Crossref","is-referenced-by-count":4,"title":["Fresh-Tissue Corneolimbal Covering Graft for Large Corneal Perforation Following Childhood Trachoma"],"prefix":"10.3928","volume":"40","author":[{"given":"Israel","family":"Kremer","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Miriam","family":"Ehrenberg","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dov","family":"Weinberger","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2308","reference":[{"key":"e_1_3_1_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(02)01558-0"},{"key":"e_1_3_1_3_2","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.83.4.399"},{"key":"e_1_3_1_4_2","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.1958.00940080900008"},{"key":"e_1_3_1_5_2","doi-asserted-by":"publisher","DOI":"10.1097\/00003226-199905000-00001"},{"key":"e_1_3_1_6_2","doi-asserted-by":"publisher","DOI":"10.1097\/00003226-200003000-00002"},{"key":"e_1_3_1_7_2","doi-asserted-by":"publisher","DOI":"10.1097\/00003226-200211000-00013"},{"key":"e_1_3_1_8_2","doi-asserted-by":"publisher","DOI":"10.3928\/1542-8877-20010701-08"},{"key":"e_1_3_1_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9394(01)00874-1"},{"key":"e_1_3_1_10_2","first-page":"1209","article-title":"Surgical treatment of active keratomalacia by \u201ccovering graft\u201d","volume":"8","author":"Ben-Sira I","year":"1972","unstructured":"Ben-Sira I, Ticho U, Yassur Y. Surgical treatment of active keratomalacia by \u201ccovering graft\u201d. Isr J Med Sci. 1972;8:1209\u20131210.","journal-title":"Isr J Med Sci"},{"key":"e_1_3_1_11_2","first-page":"237","article-title":"Corneal covering of cornea in ulcerative keratitis: clinical and histological observations","volume":"173","author":"Winter R","year":"1978","unstructured":"Winter R, Pulhorn G. Corneal covering of cornea in ulcerative keratitis: clinical and histological observations. Klin Monatsbl Augenheilkd. 1978;173:237\u2013243.","journal-title":"Klin Monatsbl Augenheilkd"},{"key":"e_1_3_1_12_2","first-page":"780","article-title":"Tectonic epikeratoplasty as an alternative to keratoplasty \u00e0 chaud?","volume":"210","author":"Bull H","year":"1997","unstructured":"Bull H, Behrens-Baumann W. Tectonic epikeratoplasty as an alternative to keratoplasty \u00e0 chaud? Klin Monatasbl Augenheilkd. 1997;210:780\u2013781.","journal-title":"Klin Monatasbl Augenheilkd"},{"key":"e_1_3_1_13_2","doi-asserted-by":"publisher","DOI":"10.1038\/sj.eye.6700670"},{"key":"e_1_3_1_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(02)01081-3"},{"key":"e_1_3_1_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.exer.2003.09.008"},{"key":"e_1_3_1_16_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1524-475x.2001.00483.x"},{"key":"e_1_3_1_17_2","doi-asserted-by":"publisher","DOI":"10.1097\/00055735-200208000-00004"},{"key":"e_1_3_1_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(02)00960-0"}],"container-title":["Ophthalmic Surgery, Lasers and Imaging Retina"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.healio.com\/ophthalmology\/cornea-external-disease\/journals\/osli\/2009-5-40-3\/%7B9f2d97b9-254c-40ed-be14-16aab4dca931%7D\/fresh-tissue-corneolimbal-covering-graft-for-large-corneal-perforation-following-childhood-trachoma.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,2,16]],"date-time":"2024-02-16T20:29:09Z","timestamp":1708115349000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.healio.com\/doi\/10.3928\/15428877-20090430-04"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,5]]},"references-count":17,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2009,5]]}},"alternative-id":["10.3928\/15428877-20090430-04"],"URL":"https:\/\/doi.org\/10.3928\/15428877-20090430-04","relation":{},"ISSN":["2325-8160","2325-8179"],"issn-type":[{"value":"2325-8160","type":"print"},{"value":"2325-8179","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,5]]}}}