{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,6,4]],"date-time":"2025-06-04T19:03:35Z","timestamp":1749063815070},"reference-count":6,"publisher":"SLACK, Inc.","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Ophthalmic Surg Lasers Imaging Retina"],"published-print":{"date-parts":[[2010,5]]},"abstract":"<jats:p>Using high-resolution spectral-domain optical coherence tomography (SD-OCT) and adaptive optics (AO) imaging, photoreceptor damage in a patient with a central macular arteriovenous malformation (AVM) and otherwise unexplained progressive vision loss was demonstrated. This patient presented with a central scotoma, a macular AVM, and no evidence of macular edema, retinal hemorrhage, or subretinal fluid. Fluorescein angiography (FA) did not reveal leakage. Over 28 years, her vision progressively worsened from 20\/25 to 20\/400. Both time-domain OCT and FA did not reveal any significant retinal abnormality. However, high-resolution SD-OCT imaging revealed clear disorganization of the outer segments and focal photo-receptor disruption adjacent to the AVM. En face AO images further revealed loss of the photoreceptors in these regions. This case demonstrates the unique finding of progressive vision loss in a patient with a congenital retinal AVM, and how high-resolution imaging can detect structural changes of the retina in patients with otherwise unexplained vision loss.<\/jats:p>","DOI":"10.3928\/15428877-20100215-99","type":"journal-article","created":{"date-parts":[[2010,3,25]],"date-time":"2010-03-25T19:05:13Z","timestamp":1269543913000},"page":"1-4","source":"Crossref","is-referenced-by-count":5,"title":["Microstructural Abnormalities Revealed by High Resolution Imaging Systems in Central Macular Arteriovenous Malformation"],"prefix":"10.3928","volume":"41","author":[{"given":"David G.","family":"Telander","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stacey S.","family":"Choi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert J.","family":"Zawadzki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Neal","family":"Berger","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John L.","family":"Keltner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John S.","family":"Werner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2308","reference":[{"key":"e_1_3_1_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2006.03.020"},{"key":"e_1_3_1_3_2","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.05-0997"},{"key":"e_1_3_1_4_2","first-page":"3317","volume-title":"Principles and Practice of Ophthalmology","author":"Ebert EM","year":"1994","unstructured":"Ebert EM, Albert DM. The Phakomatoses. In Albert DM, Jakobiec FA, Eds. Principles and Practice of Ophthalmology. Philadelphia: WB Saunders Co. 1994;3317\u20133320."},{"key":"e_1_3_1_5_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.wno.0000177301.82963.9f"},{"key":"e_1_3_1_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9394(73)91018-0"},{"key":"e_1_3_1_7_2","first-page":"53","article-title":"The Wyburn-Mason syndrome. Concomitant chiasmal and fundus vascular malformations","volume":"3","author":"Hopen G","year":"1983","unstructured":"Hopen G, Smith JL, Hoff JT, Quencer R. The Wyburn-Mason syndrome. Concomitant chiasmal and fundus vascular malformations. J Clin Neuroophthalmol. 1983;3:53\u201362.","journal-title":"J Clin Neuroophthalmol"}],"container-title":["Ophthalmic Surgery, Lasers and Imaging Retina"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.healio.com\/doiresolver?doi=10.3928\/15428877-20100215-99","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,3]],"date-time":"2023-05-03T06:46:59Z","timestamp":1683096419000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.healio.com\/doi\/10.3928\/15428877-20100215-99"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,5]]},"references-count":6,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2010,5]]}},"alternative-id":["10.3928\/15428877-20100215-99"],"URL":"https:\/\/doi.org\/10.3928\/15428877-20100215-99","relation":{},"ISSN":["2325-8160","2325-8179"],"issn-type":[{"value":"2325-8160","type":"print"},{"value":"2325-8179","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,5]]}}}