{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T03:39:38Z","timestamp":1790912378147,"version":"4.1.0"},"reference-count":37,"publisher":"SLACK, Inc.","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Ophthalmic Surg Lasers Imaging"],"published-print":{"date-parts":[[2012,5]]},"abstract":"<jats:sec>\n            <jats:title>BACKGROUND AND OBJECTIVE:<\/jats:title>\n            <jats:p>To evaluate corneal wound healing after femtosecond laser-assisted keratoplasty (FLAK) using in vivo confocal microscopy (IVCM).<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>PATIENTS AND METHODS:<\/jats:title>\n            <jats:p>Prospective, interventional, consecutive case series of 17 eyes after mushroom-shaped FLAK. IVCM was performed preoperatively and at 1, 3, 6, and 12 months postoperatively to assess wound healing.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>RESULTS:<\/jats:title>\n            <jats:p>Mean keratocyte activation grade increased from preoperative levels to 1 month postoperatively in both the central (0.41 \u00b1 0.62 to 1.73 \u00b1 1.03) and peripheral (0.47 \u00b1 0.52 to 1.57 \u00b1 1.09) cornea, then gradually decreased through 12 months. Dendritic cells increased from preoperatively to 1 month postoperatively in both the central (0.71 \u00b1 0.83 to 1.33 \u00b1 0.98) and peripheral (0.79 \u00b1 0.70 to 1.42 \u00b1 0.90) cornea, then gradually decreased until 6 months postoperatively. Stromal reinnervation was 1 month postoperatively in 8 patients (50%). By 12 months, sub-epithelial nerves were observed centrally in 5 patients (45.5%).<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>CONCLUSION:<\/jats:title>\n            <jats:p>IVCM after FLAK shows an initial increase in keratocyte activation and dendritic cells that decrease over time. Corneal reinnervation is seen as early as 1 month postoperatively.<\/jats:p>\n          <\/jats:sec>","DOI":"10.3928\/15428877-20120209-01","type":"journal-article","created":{"date-parts":[[2012,2,13]],"date-time":"2012-02-13T16:58:55Z","timestamp":1329152335000},"page":"205-213","source":"Crossref","is-referenced-by-count":29,"title":["In Vivo Confocal Microscopic Evaluation of Corneal Wound Healing After Femtosecond Laser-Assisted Keratoplasty"],"prefix":"10.3928","volume":"43","author":[{"given":"Roni M.","family":"Shtein","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kurt H.","family":"Kelley","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David C.","family":"Musch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alan","family":"Sugar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shahzad I.","family":"Mian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2308","reference":[{"key":"e_1_3_1_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(03)00463-9"},{"key":"e_1_3_1_3_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-2008-1045677"},{"key":"e_1_3_1_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(99)90265-8"},{"key":"e_1_3_1_5_2","doi-asserted-by":"publisher","DOI":"10.3928\/1081-597X-20040701-15"},{"key":"e_1_3_1_6_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.ico.0000179739.31196.e8"},{"key":"e_1_3_1_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2006.11.043"},{"key":"e_1_3_1_8_2","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.2008.148346"},{"key":"e_1_3_1_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2009.05.003"},{"key":"e_1_3_1_10_2","doi-asserted-by":"publisher","DOI":"10.1097\/ICO.0b013e31815b7d50"},{"key":"e_1_3_1_11_2","doi-asserted-by":"publisher","DOI":"10.1080\/02713680802535255"},{"key":"e_1_3_1_12_2","doi-asserted-by":"publisher","DOI":"10.1097\/00003226-200108000-00002"},{"key":"e_1_3_1_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.clae.2006.03.005"},{"key":"e_1_3_1_14_2","doi-asserted-by":"publisher","DOI":"10.1177\/112067210701700604"},{"key":"e_1_3_1_15_2","doi-asserted-by":"publisher","DOI":"10.1097\/ICO.0b013e3180318107"},{"key":"e_1_3_1_16_2","first-page":"513","article-title":"Corneal reinnervation following penetrating keratoplasty-correlation of esthesiometry and confocal microscopy","volume":"5","author":"Richter A","year":"1996","unstructured":"Richter A, Slowik C, Somodi S, Vick HP, Guthoff R. 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