{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T18:46:52Z","timestamp":1790880412051,"version":"4.1.0"},"reference-count":14,"publisher":"SLACK, Inc.","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Ophthalmic Surg Lasers Imaging"],"published-print":{"date-parts":[[2012,5]]},"abstract":"<jats:sec>\n            <jats:title>BACKGROUND AND OBJECTIVE:<\/jats:title>\n            <jats:p>To evaluate wound morphology and integrity using contrast-enhanced spectral-domain optical coherence tomography (SD-OCT).<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>PATIENTS AND METHODS:<\/jats:title>\n            <jats:p>Eighteen patients (18 eyes) undergoing unilateral routine cataract surgery were enrolled. SD-OCT imaging of the corneal wound was performed immediately following cataract surgery and on postoperative day 1. A topical contrast agent, prednisolone acetate 1%, was used to help evaluate wound integrity. OCT features of the corneal incision and changes in wound interface reflectivity after administration of topical prednisolone acetate 1% were analyzed. Main outcome measures were quantitative and qualitative description of wound morphology and contrast enhancement of the wound interface.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>RESULTS:<\/jats:title>\n            <jats:p>\n              Internal wound gape was found in 89% of eyes. Gape area decreased by 43% from days 0 to 1 (462 vs 273 \u03bcm\n              <jats:sup>2<\/jats:sup>\n              ;\n              <jats:italic>P<\/jats:italic>\n              &lt; .01). Contrast enhancement at the wound interface was seen in 56% of eyes on day 0 compared to 17% on day 1 following application of prednisolone acetate 1% (\n              <jats:italic>P<\/jats:italic>\n              &lt; .05). Decreased intraocular pressure correlated with increased contrast enhancement (\n              <jats:italic>P<\/jats:italic>\n              &lt; .05).\n            <\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>CONCLUSION:<\/jats:title>\n            <jats:p>Wound morphology evolves during the early postoperative period. Wound gape and ingress of a topical contrast agent decrease during the first 24 hours following surgery. Contrast enhancement at the wound interface increases as the intraocular pressure decreases.<\/jats:p>\n          <\/jats:sec>","DOI":"10.3928\/15428877-20120308-05","type":"journal-article","created":{"date-parts":[[2012,3,15]],"date-time":"2012-03-15T21:23:02Z","timestamp":1331846582000},"page":"222-228","source":"Crossref","is-referenced-by-count":10,"title":["Evaluation of Clear Corneal Wound Dynamics With Contrast-Enhanced Spectral-Domain Optical Coherence Tomography"],"prefix":"10.3928","volume":"43","author":[{"given":"Preeya K.","family":"Gupta","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Justis P.","family":"Ehlers","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Terry","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2308","reference":[{"key":"e_1_3_1_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2005.02.028"},{"key":"e_1_3_1_3_2","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.123.5.613"},{"key":"e_1_3_1_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrs.2008.05.026"},{"key":"e_1_3_1_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrs.2008.01.038"},{"key":"e_1_3_1_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrs.2008.11.034"},{"key":"e_1_3_1_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(03)00733-4"},{"key":"e_1_3_1_8_2","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.10-6195"},{"key":"e_1_3_1_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrs.2006.09.016"},{"key":"e_1_3_1_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2009.12.008"},{"key":"e_1_3_1_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.survophthal.2004.01.003"},{"key":"e_1_3_1_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrs.2007.06.039"},{"key":"e_1_3_1_13_2","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.123.5.643"},{"key":"e_1_3_1_14_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2591.1995.tb00153.x"},{"key":"e_1_3_1_15_2","doi-asserted-by":"publisher","DOI":"10.1089\/jop.2006.0070"}],"container-title":["Ophthalmic Surgery, Lasers and Imaging Retina"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.healio.com\/doiresolver?doi=10.3928\/15428877-20120308-05","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,3]],"date-time":"2023-05-03T06:29:16Z","timestamp":1683095356000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.healio.com\/doi\/10.3928\/15428877-20120308-05"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,5]]},"references-count":14,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2012,5]]}},"alternative-id":["10.3928\/15428877-20120308-05"],"URL":"https:\/\/doi.org\/10.3928\/15428877-20120308-05","relation":{},"ISSN":["2325-8160","2325-8179"],"issn-type":[{"value":"2325-8160","type":"print"},{"value":"2325-8179","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,5]]}}}