{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T07:17:28Z","timestamp":1772954248436,"version":"3.50.1"},"reference-count":18,"publisher":"SLACK, Inc.","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Ophthalmic Surg Lasers Imaging Retina"],"published-print":{"date-parts":[[2013,1]]},"abstract":"\n BACKGROUND AND OBJECTIVE:<\/jats:title>\n To evaluate the efficacy of ranibizumab in the treatment of choroidal neovascularization secondary to presumed ocular histoplasmosis syndrome.<\/jats:p>\n <\/jats:sec>\n \n PATIENTS AND METHODS:<\/jats:title>\n Patients enrolled in the ranibizumab group received a monthly intravitreal injection of 0.5 mg of ranibizumab. Patients in the photodynamic therapy (PDT) group received a quarterly dosing of intravenous verteporfin coupled with PDT.<\/jats:p>\n <\/jats:sec>\n \n RESULTS:<\/jats:title>\n Mean change in ETDRS visual acuity at 1 year was 19.6 letters in the ranibizumab group versus 21 letters in the PDT group. All patients in the PDT group required rescue ranibizumab therapy. Four of five patients (80%) in the ranibizumab group and one of two patients (50%) in the PDT group showed a greater than 15 letter gain at 1 year.<\/jats:p>\n <\/jats:sec>\n \n CONCLUSION:<\/jats:title>\n Ranibizumab appears to be a safe and effective treatment option for choroidal neovascularization secondary to the presumed ocular histoplasmosis syndrome.<\/jats:p>\n <\/jats:sec>","DOI":"10.3928\/23258160-20121221-07","type":"journal-article","created":{"date-parts":[[2013,1,9]],"date-time":"2013-01-09T02:49:34Z","timestamp":1357699774000},"page":"17-21","source":"Crossref","is-referenced-by-count":14,"title":["Ranibizumab Versus Photodynamic Therapy for Presumed Ocular Histoplasmosis Syndrome"],"prefix":"10.3928","volume":"44","author":[{"given":"Kamalesh J.","family":"Ramaiya","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kevin J.","family":"Blinder","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas","family":"Ciulla","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Blake","family":"Cooper","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gaurav K.","family":"Shah","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2308","reference":[{"key":"e_1_3_1_2_2","first-page":"515","article-title":"The natural course of active choroidal lesions in the presumed ocular histoplasmosis syndrome","volume":"77","author":"Gutman FA","year":"1979","unstructured":"Gutman FA. 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