{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,5,3]],"date-time":"2023-05-03T04:07:44Z","timestamp":1683086864294},"reference-count":13,"publisher":"SLACK, Inc.","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Ophthalmic Surg Lasers Imaging Retina"],"published-print":{"date-parts":[[2015,2]]},"abstract":"<jats:sec>\n            <jats:title>BACKGROUND AND OBJECTIVE:<\/jats:title>\n            <jats:p>To study eyes with no light perception (NLP) occurring secondary to neovascular age-related macular degeneration (AMD).<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>PATIENTS AND METHODS:<\/jats:title>\n            <jats:p>Records of consecutive patients with neovascular AMD seen during a 10-year period were reviewed to ascertain which patients had NLP due to neovascular AMD.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>RESULTS:<\/jats:title>\n            <jats:p>\n              Ten of 1,150 patients (0.9%) with neovascular AMD had NLP in one eye (study eye) from neovascular AMD. All 10 patients had bilateral neovascular AMD. Each study eye had a large macular disciform scar and 360\u00b0 peripapillary subretinal fibrovascular tissue. Seven of nine (78%) study eyes had optic disc pallor, versus none of eight fellow eyes (\n              <jats:italic>P<\/jats:italic>\n              = .04). Mean fellow eye vision was 20\/231, ranging from 20\/50 to NLP (\n              <jats:italic>P<\/jats:italic>\n              = .006 vs study eyes). No seeing fellow eye had choroidal neovascularization encircling the optic disc (\n              <jats:italic>P<\/jats:italic>\n              = .0004).\n            <\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>CONCLUSION:<\/jats:title>\n            <jats:p>NLP from neovascular AMD is associated with 360\u00b0 peripapillary subretinal fibrosis. This fibrosis may cause chronic ischemic optic neuropathy contributing to extinguished vision.<\/jats:p>\n            <jats:p>\n              <jats:bold>\n                [\n                <jats:italic>Ophthalmic Surg Lasers Imaging Retina.<\/jats:italic>\n                2015;46:229\u2013234.]\n              <\/jats:bold>\n            <\/jats:p>\n          <\/jats:sec>","DOI":"10.3928\/23258160-20150213-03","type":"journal-article","created":{"date-parts":[[2015,2,23]],"date-time":"2015-02-23T13:56:13Z","timestamp":1424699773000},"page":"229-234","source":"Crossref","is-referenced-by-count":2,"title":["Neovascular Age-Related Macular Degeneration Associated With No Light Perception"],"prefix":"10.3928","volume":"46","author":[{"given":"Gary C.","family":"Brown","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mahdi M.","family":"Basha","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Melissa M.","family":"Brown","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2308","reference":[{"key":"e_1_3_1_2_2","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.119.10.1417"},{"key":"e_1_3_1_3_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa054481"},{"key":"e_1_3_1_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2006.07.017"},{"key":"e_1_3_1_5_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1102673"},{"key":"e_1_3_1_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2006.09.043"},{"key":"e_1_3_1_7_2","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.85.3.327"},{"key":"e_1_3_1_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(86)33555-3"},{"key":"e_1_3_1_9_2","first-page":"1","article-title":"Optical coherence tomography for age-related macular degeneration and diabetic macular edema: an evidence-based analysis","volume":"9","author":"Health Quality Ontario","year":"2009","unstructured":"Health Quality Ontario. Optical coherence tomography for age-related macular degeneration and diabetic macular edema: an evidence-based analysis. Ont Health Technol Assess Ser. 2009;9:1\u201322.","journal-title":"Ont Health Technol Assess Ser"},{"key":"e_1_3_1_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2010.01.007"},{"key":"e_1_3_1_11_2","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.66.2.77"},{"key":"e_1_3_1_12_2","doi-asserted-by":"publisher","DOI":"10.1038\/sj.eye.6700691"},{"key":"e_1_3_1_13_2","first-page":"473","article-title":"Vision and quality of life","volume":"97","author":"Brown GC","year":"1999","unstructured":"Brown GC. Vision and quality of life. Trans Am Ophthalmol Soc. 1999;97:473\u2013512.","journal-title":"Trans Am Ophthalmol Soc"},{"key":"e_1_3_1_14_2","doi-asserted-by":"publisher","DOI":"10.1097\/ICU.0b013e3282fc9c35"}],"container-title":["Ophthalmic Surgery, Lasers and Imaging Retina"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.healio.com\/doiresolver?doi=10.3928\/23258160-20150213-03","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,3]],"date-time":"2023-05-03T00:13:55Z","timestamp":1683072835000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.healio.com\/doi\/10.3928\/23258160-20150213-03"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,2]]},"references-count":13,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2015,2]]}},"alternative-id":["10.3928\/23258160-20150213-03"],"URL":"https:\/\/doi.org\/10.3928\/23258160-20150213-03","relation":{},"ISSN":["2325-8160","2325-8179"],"issn-type":[{"value":"2325-8160","type":"print"},{"value":"2325-8179","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,2]]}}}