{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T14:43:49Z","timestamp":1790952229407,"version":"4.1.0"},"reference-count":5,"publisher":"SLACK, Inc.","issue":"10","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Ophthalmic Surg Lasers Imaging Retina"],"published-print":{"date-parts":[[2015,11]]},"abstract":"<jats:sec>\n                    <jats:title>BACKGROUND AND OBJECTIVE:<\/jats:title>\n                    <jats:p>\n                      ReSure Sealant (Ocular Therapeutix, Bedford, MA) is an ocular sealant that demonstrated both safety and effectiveness in a prospective, randomized clinical trial for sealing clear corneal incisions following cataract surgery and intraocular lens placement in adults.\n                      <jats:xref ref-type=\"bibr\">1<\/jats:xref>\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>PATIENTS AND METHODS:<\/jats:title>\n                    <jats:p>This is the first literature report of ReSure Sealant used for the closure of 23-gauge (G) pars plana vitrectomy (PPV) sclerotomies. A 70-year-old pseudophakic female with a history of epiretinal membrane and branch retinal vein occlusion of the right eye underwent 23-G PPV, membrane peel, and air-fluid exchange and was found to have leaking subconjunctival air at the end of the case. A linear conjunctival incision was performed to access the sclerotomy site. The incisions were then carefully dried before the sealant was applied to seal both the sclera and conjunctiva.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS:<\/jats:title>\n                    <jats:p>After polymerization, the sealant formed a polyethylene glycol (PEG) hydrogel that was 89% water and 9.44% PEG. PEG is a synthetic material that is non-toxic and inert and, thus, suitable for use in medical products.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSION:<\/jats:title>\n                    <jats:p>ReSure Sealant may be a safe, quick method to close sclerotomy wounds in select cases.<\/jats:p>\n                    <jats:p>\n                      <jats:bold>\n                        [\n                        <jats:italic>Ophthalmic Surg Lasers Imaging Retina.<\/jats:italic>\n                        2015;46:1042\u20131044.]\n                      <\/jats:bold>\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.3928\/23258160-20151027-09","type":"journal-article","created":{"date-parts":[[2015,11,24]],"date-time":"2015-11-24T13:57:24Z","timestamp":1448373444000},"page":"1042-1044","source":"Crossref","is-referenced-by-count":13,"title":["ReSure Sealant for Pars Plana Vitrectomy Wound Closure"],"prefix":"10.3928","volume":"46","author":[{"given":"Vincent Y.","family":"Ho","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gaurav K.","family":"Shah","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Enchun M.","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2308","reference":[{"key":"e_1_3_1_2_2","unstructured":"Summary of Safety and Effectiveness Data for the ReSure Sealant PMA P13004. http:\/\/www.accessdata.fda.gov\/cdrh_docs\/pdf13\/P130004b.pdf."},{"key":"e_1_3_1_3_2","doi-asserted-by":"publisher","DOI":"10.1038\/eye.2008.175"},{"key":"e_1_3_1_4_2","doi-asserted-by":"publisher","DOI":"10.1097\/IAE.0b013e3181cdf398"},{"issue":"10","key":"e_1_3_1_5_2","first-page":"1006","article-title":"Fibrin glue for closing conjunctival wounds in ophthalmic surgery","volume":"101","author":"Krzizok T","year":"2004","unstructured":"Krzizok T. Fibrin glue for closing conjunctival wounds in ophthalmic surgery. Ophthalmologe. 2004;101(10):1006\u20131010.","journal-title":"Ophthalmologe"},{"key":"e_1_3_1_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2007.02.038"}],"container-title":["Ophthalmic Surgery, Lasers and Imaging Retina"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.healio.com\/doiresolver?doi=10.3928\/23258160-20151027-09","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,3]],"date-time":"2023-05-03T01:13:08Z","timestamp":1683076388000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.healio.com\/doi\/10.3928\/23258160-20151027-09"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,11]]},"references-count":5,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2015,11]]}},"alternative-id":["10.3928\/23258160-20151027-09"],"URL":"https:\/\/doi.org\/10.3928\/23258160-20151027-09","relation":{},"ISSN":["2325-8160","2325-8179"],"issn-type":[{"value":"2325-8160","type":"print"},{"value":"2325-8179","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,11]]}}}