{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,17]],"date-time":"2026-04-17T19:41:50Z","timestamp":1776454910937,"version":"3.51.2"},"reference-count":23,"publisher":"SLACK, Inc.","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Ophthalmic Surg Lasers Imaging Retina"],"published-print":{"date-parts":[[2017,6,1]]},"abstract":"<jats:sec>\n                    <jats:title>BACKGROUND AND OBJECTIVE:<\/jats:title>\n                    <jats:p>To determine outcomes of intravitreal ranibizumab (IVR) (Lucentis; Genentech, South San Francisco, CA) versus bevacizumab (IVB) (Avastin; Genentech, South San Francisco, CA) for treatment of macular edema (ME) secondary to retinal vein occlusion (RVO) in routine clinical practice.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>PATIENTS AND METHODS:<\/jats:title>\n                    <jats:p>A retrospective study identified treatment-na\u00efve patients with ME secondary to RVO where treatment with either IVB or IVR was initiated. Retreatment criteria were based on ophthalmic examination and\/or spectral-domain optical coherence tomography findings.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS:<\/jats:title>\n                    <jats:p>\n                      Central RVO\/hemi-RVO cohort: At 12 months, change in visual acuity (VA) (IVR: +12.9 letters, IVB +6.9 letters;\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = .53), central subfield thickness (CST) (IVR: \u2212144.1 \u03bcm, IVB: \u2212153.9 \u03bcm;\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = .88), and number of injections (IVR: 5.40 injections, IVB: 5.64 injections;\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = .70) were not different between groups. Branch RVO cohort: At 12-month follow-up, no differences in change in VA (IVR: +15.2 letters, IVB: +10.6 letters;\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = .46), CST (IVR: \u221223.1 \u03bcm, IVB: \u221291.4 \u03bcm;\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = .16), or number of injections (IVR: 5.93 injections, IVB: 5.13 injections;\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = .15) were noted.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSION:<\/jats:title>\n                    <jats:p>There is no notable difference in outcome between IVR and IVB when treating ME from RVO in routine clinical practice.<\/jats:p>\n                    <jats:p>\n                      <jats:bold>\n                        [\n                        <jats:italic toggle=\"yes\">Ophthalmic Surg Lasers Imaging Retina.<\/jats:italic>\n                        2017;48:465\u2013472.]\n                      <\/jats:bold>\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.3928\/23258160-20170601-04","type":"journal-article","created":{"date-parts":[[2017,6,14]],"date-time":"2017-06-14T10:42:48Z","timestamp":1497436968000},"page":"465-472","source":"Crossref","is-referenced-by-count":10,"title":["Comparison of Ranibizumab and Bevacizumab for Macular Edema Secondary to Retinal Vein Occlusions in Routine Clinical Practice"],"prefix":"10.3928","volume":"48","author":[{"given":"Mehnaz","family":"Khan","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karen M.","family":"Wai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fabiana Q.","family":"Silva","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sunil","family":"Srivastava","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Justis P.","family":"Ehlers","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aleksandra","family":"Rachitskaya","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amy","family":"Babiuch","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ryan","family":"Deasy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter K.","family":"Kaiser","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrew 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