{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,29]],"date-time":"2026-07-29T04:26:15Z","timestamp":1785299175537,"version":"3.55.0"},"reference-count":13,"publisher":"SLACK, Inc.","issue":"9","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Ophthalmic Surg Lasers Imaging Retina"],"published-print":{"date-parts":[[2018,9]]},"abstract":"<jats:sec>\n            <jats:title>BACKGROUND AND OBJECTIVES:<\/jats:title>\n            <jats:p>To determine the rate of ocular hypertension (OHT) after dexamethasone intravitreal implant in routine clinical practice and identify patient characteristics associated with a risk for glaucoma surgery.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>PATIENTS AND METHODS:<\/jats:title>\n            <jats:p>The charts of 260 eyes from 221 patients with diabetic macular edema, retinal vein occlusion, uveitis, and macular edema secondary to various causes treated with one or more dexamethasone implants were reviewed. Intraocular pressure (IOP), medications, and glaucoma interventions were collected before and after implantation.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>RESULTS:<\/jats:title>\n            <jats:p>\n              The mean baseline IOP was 14.3 mm Hg \u00b1 3.6 mm Hg, and after receiving dexamethasone implant(s), 26.2% and 7.7% of patients had IOP greater than 25 mm Hg and 35 mm Hg, respectively. There was evidence (\n              <jats:italic>P<\/jats:italic>\n              &lt; .001) of an association between preexisting glaucoma or glaucoma suspect status (103 eyes) and need for glaucoma surgery, and 4.62% (12 eyes) required glaucoma surgery.\n            <\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>CONCLUSIONS:<\/jats:title>\n            <jats:p>Secondary OHT induced by the dexamethasone implant can usually be controlled by medications, but the incidence of OHT requiring glaucoma surgery was high (4.62%) in our study relative to rates previously reported in the literature. All patients, especially those with preexisting glaucoma, should be advised of the possible need for glaucoma surgery prior to undergoing treatment with the dexamethasone implant.<\/jats:p>\n            <jats:p>\n              <jats:bold>\n                [\n                <jats:italic>Ophthalmic Surg Lasers Imaging Retina<\/jats:italic>\n                . 2018;49:680\u2013685.]\n              <\/jats:bold>\n            <\/jats:p>\n          <\/jats:sec>","DOI":"10.3928\/23258160-20180831-05","type":"journal-article","created":{"date-parts":[[2018,9,17]],"date-time":"2018-09-17T17:35:58Z","timestamp":1537205758000},"page":"680-685","source":"Crossref","is-referenced-by-count":15,"title":["Secondary Ocular Hypertension and the Risk of Glaucoma Surgery After Dexamethasone Intravitreal Implant in Routine Clinical Practice"],"prefix":"10.3928","volume":"49","author":[{"given":"Kornwipa","family":"Hemarat","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jacquelyn D.","family":"Kemmer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Travis C.","family":"Porco","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander M.","family":"Eaton","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rahul N.","family":"Khurana","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jay M.","family":"Stewart","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2308","reference":[{"key":"e_1_3_1_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2011.05.014"},{"key":"e_1_3_1_3_2","doi-asserted-by":"publisher","DOI":"10.1001\/archophthalmol.2010.339"},{"key":"e_1_3_1_4_2","doi-asserted-by":"publisher","DOI":"10.1097\/IAE.0000000000001004"},{"key":"e_1_3_1_5_2","doi-asserted-by":"publisher","DOI":"10.5301\/ejo.5000787"},{"key":"e_1_3_1_6_2","doi-asserted-by":"publisher","DOI":"10.1089\/jop.2012.0253"},{"issue":"9","key":"e_1_3_1_7_2","first-page":"421","article-title":"[Effects of ozurdex on intraocular pressure. A real life clinical practice study]","volume":"90","author":"Jimenez-Gomez B","year":"2015","unstructured":"Jimenez-Gomez B, Gonzalez-Montpetit M, Fonollosa Calduch A, Orive Banuelos A, Valsero Franco S. [Effects of ozurdex on intraocular pressure. A real life clinical practice study]. Arch Soc Esp Oftalmol. 2015;90(9):421\u2013425.","journal-title":"Arch Soc Esp Oftalmol"},{"key":"e_1_3_1_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jfo.2014.03.001"},{"key":"e_1_3_1_9_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00347-012-2737-2"},{"key":"e_1_3_1_10_2","doi-asserted-by":"publisher","DOI":"10.1159\/000438759"},{"key":"e_1_3_1_11_2","doi-asserted-by":"publisher","DOI":"10.1097\/IAE.0000000000001364"},{"key":"e_1_3_1_12_2","doi-asserted-by":"publisher","DOI":"10.1097\/IAE.0000000000001369"},{"key":"e_1_3_1_13_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12886-015-0106-z"},{"key":"e_1_3_1_14_2","first-page":"1255","article-title":"Real-world assessment of intravitreal dexamethasone implant (0.7 mg) in patients with macular edema: The CHROME study","volume":"9","author":"Lam WC","year":"2015","unstructured":"Lam WC, Albiani DA, Yoganathan P, et al. Real-world assessment of intravitreal dexamethasone implant (0.7 mg) in patients with macular edema: The CHROME study. Clin Ophthalmol. 2015;9:1255\u20131268.","journal-title":"Clin Ophthalmol"}],"container-title":["Ophthalmic Surgery, Lasers and Imaging Retina"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.healio.com\/doiresolver?doi=10.3928\/23258160-20180831-05","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,2]],"date-time":"2023-05-02T18:53:37Z","timestamp":1683053617000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.healio.com\/doi\/10.3928\/23258160-20180831-05"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,9]]},"references-count":13,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2018,9]]}},"alternative-id":["10.3928\/23258160-20180831-05"],"URL":"https:\/\/doi.org\/10.3928\/23258160-20180831-05","relation":{},"ISSN":["2325-8160","2325-8179"],"issn-type":[{"value":"2325-8160","type":"print"},{"value":"2325-8179","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,9]]}}}