{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T06:49:27Z","timestamp":1791960567760,"version":"4.3.4"},"reference-count":13,"publisher":"SLACK, Inc.","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Ophthalmic Surg Lasers Imaging Retina"],"published-print":{"date-parts":[[2019,5]]},"abstract":"<jats:p>Optic nerve aplasia (ONA) is a rare phenomenon characterized by absence of the optic nerve, retinal blood vessels, and retinal ganglion cells. The authors report a case of optic nerve aplasia in association with congenital cytomegalovirus (CMV) infection, conveyed through multimodal imaging including color fundus photography, fluorescein angiography, and B-scan ultrasonography. Furthermore, the authors review the common ocular findings and previously reported cases of ONA in congenital CMV infection. Screening and counseling can be performed to advise parents about the potential risks and severity of this rare clinical manifestation.<\/jats:p>\n          <jats:p>\n            <jats:bold>\n              [\n              <jats:italic>Ophthalmic Surg Lasers Imaging Retina<\/jats:italic>\n              . 2019;50:e171\u2013e175.]\n            <\/jats:bold>\n          <\/jats:p>","DOI":"10.3928\/23258160-20190503-18","type":"journal-article","created":{"date-parts":[[2019,5,17]],"date-time":"2019-05-17T17:20:14Z","timestamp":1558113614000},"source":"Crossref","is-referenced-by-count":6,"title":["Optic Nerve Aplasia, Chorioretinal Hypoplasia, and Microcornea After In Utero Infection With Cytomegalovirus"],"prefix":"10.3928","volume":"50","author":[{"given":"Nicole","family":"Koulisis","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stavros N.","family":"Moysidis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Natalia F.","family":"Callaway","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steven J.","family":"Ryder","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Camila V.","family":"Ventura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eddy","family":"Mesa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Craig A.","family":"McKeown","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Audina M.","family":"Berrocal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2308","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.4103\/2008-322X.163779"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.122.1.125"},{"issue":"10","key":"e_1_3_2_4_2","first-page":"465","article-title":"Aplasia and hypoplasia of the optic nerve. Comparison of 2 cases","volume":"48","author":"Pisaturo C","year":"1996","unstructured":"Pisaturo C, Dolci A, Pessagno A, Padua GL, Dassio DA, De Negri M. Aplasia and hypoplasia of the optic nerve. Comparison of 2 cases. Minerva Pediatr. 1996;48(10):465\u2013469.","journal-title":"Minerva Pediatr"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1097\/INF.0000000000001599"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1067\/mpa.2000.103870"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00431-015-2513-9"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9394(76)90134-3"},{"key":"e_1_3_2_9_2","first-page":"2015","article-title":"Rare case of unilateral optic nerve aplasia","author":"Mannan R","year":"2015","unstructured":"Mannan R, Chandra P. Rare case of unilateral optic nerve aplasia. 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J Pediatr Ophthalmol Strabismus. 2011;48(6):e1\u2013e3.","journal-title":"J Pediatr Ophthalmol Strabismus"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9394(77)90569-4"}],"container-title":["Ophthalmic Surgery, Lasers and Imaging Retina"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.healio.com\/doiresolver?doi=10.3928\/23258160-20190503-18","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,3]],"date-time":"2023-05-03T06:51:37Z","timestamp":1683096697000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.healio.com\/doi\/10.3928\/23258160-20190503-18"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,5]]},"references-count":13,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2019,5]]}},"alternative-id":["10.3928\/23258160-20190503-18"],"URL":"https:\/\/doi.org\/10.3928\/23258160-20190503-18","relation":{},"ISSN":["2325-8160","2325-8179"],"issn-type":[{"value":"2325-8160","type":"print"},{"value":"2325-8179","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,5]]}}}