{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,8]],"date-time":"2026-05-08T05:15:35Z","timestamp":1778217335267,"version":"3.51.4"},"reference-count":31,"publisher":"SLACK, Inc.","issue":"9","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Ophthalmic Surg Lasers Imaging Retina"],"published-print":{"date-parts":[[2019,9]]},"abstract":"\n BACKGROUND AND OBJECTIVE:<\/jats:title>\n To compare choriocapillaris (CC) flow voids (FVs) throughout the macula in patients with age-related macular degeneration (AMD) and geographic atrophy (GA) to age-similar controls using swept-source optical coherence tomography angiography (SS-OCTA).<\/jats:p>\n <\/jats:sec>\n \n PATIENTS AND METHODS:<\/jats:title>\n In this cross-sectional study, 12 subjects with GA secondary to nonexudative AMD and 12 age-similar controls participated. SS-OCTA was performed using a 6 mm \u00d7 6 mm scanning pattern. CC FVs were calculated using a one-standard deviation thresholding method developed from a normal database.<\/jats:p>\n <\/jats:sec>\n \n RESULTS:<\/jats:title>\n \n CC FVs were significantly increased in patients with GA compared with age-similar controls (\n P<\/jats:italic>\n < .001). FVs within 2\u00b0 of GA were significantly increased compared with the area outside 2\u00b0 (\n P<\/jats:italic>\n < .001). FVs beyond 2\u00b0 of GA were significantly increased compared with age-similar controls (\n P<\/jats:italic>\n < .001).\n <\/jats:p>\n <\/jats:sec>\n \n CONCLUSIONS:<\/jats:title>\n FV analysis of in vivo CC images revealed diffuse CC perfusion deficits throughout the macular region in subjects with GA secondary to nonexudative AMD.<\/jats:p>\n \n \n [\n Ophthalmic Surg Lasers Imaging Retina<\/jats:italic>\n . 2019;50:e229\u2013e235.]\n <\/jats:bold>\n <\/jats:p>\n <\/jats:sec>","DOI":"10.3928\/23258160-20190905-14","type":"journal-article","created":{"date-parts":[[2019,10,7]],"date-time":"2019-10-07T19:15:34Z","timestamp":1570475734000},"source":"Crossref","is-referenced-by-count":8,"title":["Quantifying Choriocapillaris Flow Voids in Patients With Geographic Atrophy Using Swept-Source OCT Angiography"],"prefix":"10.3928","volume":"50","author":[{"given":"Nicholas T.","family":"Rinella","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hao","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qinqin","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cathrine","family":"Keiner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Catherine E.","family":"Oldenburg","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jacque L.","family":"Duncan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ruikang K.","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel M.","family":"Schwartz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2308","reference":[{"issue":"1","key":"e_1_3_1_2_2","first-page":"94","article-title":"A study of the choroidal circulation of the eye in man","volume":"88","author":"Wybar KC","year":"1954","unstructured":"Wybar KC. 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