{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,6]],"date-time":"2026-03-06T04:18:17Z","timestamp":1772770697686,"version":"3.50.1"},"reference-count":19,"publisher":"SLACK, Inc.","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Ophthalmic Surg Lasers Imaging Retina"],"published-print":{"date-parts":[[2022,6]]},"abstract":"<jats:p>Bilateral diffuse uveal melanocytic proliferation (BDUMP) is a rare paraneoplastic syndrome. Diagnosis can be difficult and treatment guidelines are ill-defined. A 73-year-old man with poorly differentiated high grade urothelial carcinoma of the ureter metastatic to the liver, lungs, lymph nodes, and pelvis treated with chemotherapy and immunotherapy reported gradual vision loss. Optical coherence tomography (OCT) demonstrated intraretinal and subretinal fluid with hyperreflective subretinal deposits and focal, deeply pigmented choroidal lesions. Irregular hyperpigmentation of the retinal pigment epithelium (RPE) with a \u201cleopard spot\u201d pattern on fundus autofluorescence (FAF) supported the diagnosis of BDUMP. Multiple plasmapheresis sessions did not result in sustained clinical improvement.<\/jats:p>\n          <jats:p>\n            <jats:bold>\n              [\n              <jats:italic>Ophthalmic Surg Lasers Imaging Retina<\/jats:italic>\n              2022;53(6): 350\u2013353.]\n            <\/jats:bold>\n          <\/jats:p>","DOI":"10.3928\/23258160-20220604-01","type":"journal-article","created":{"date-parts":[[2022,6,20]],"date-time":"2022-06-20T20:11:56Z","timestamp":1655755916000},"page":"350-353","source":"Crossref","is-referenced-by-count":5,"title":["A Case of Bilateral Diffuse Uveal Melanocytic Proliferation in the Setting of Urothelial Carcinoma of the Ureter: A Failed Response to Plasmapheresis"],"prefix":"10.3928","volume":"53","author":[{"given":"Lauren C.","family":"Kiryakoza","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. Daniel","family":"Diaz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joshua","family":"Priluck","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Janet","family":"Davis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicolas A.","family":"Yannuzzi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2308","reference":[{"key":"e_1_3_1_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.survophthal.2003.08.005"},{"key":"e_1_3_1_3_2","doi-asserted-by":"publisher","DOI":"10.1097\/IIO.0000000000000156"},{"key":"e_1_3_1_4_2","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.1990.01070060075053"},{"key":"e_1_3_1_5_2","doi-asserted-by":"publisher","DOI":"10.1001\/jamaophthalmol.2014.311"},{"key":"e_1_3_1_6_2","doi-asserted-by":"publisher","DOI":"10.1186\/s40942-016-0038-7"},{"key":"e_1_3_1_7_2","first-page":"763","volume-title":"The Retinal Atlas","author":"Freund KB","year":"2017","unstructured":"Freund KB, Sarraf D, Mieler W, Yannuzzi L. Oncology. In: Freund KB, Sarraf D, Mieler W, Yannuzzi L, eds. The Retinal Atlas. 2nd ed. Elsevier; 2017:763\u2013912:chapter 8.","edition":"2"},{"key":"e_1_3_1_8_2","doi-asserted-by":"publisher","DOI":"10.3928\/23258160-20200702-07"},{"key":"e_1_3_1_9_2","doi-asserted-by":"publisher","DOI":"10.1097\/IAE.0000000000000119"},{"key":"e_1_3_1_10_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-200102000-00009"},{"key":"e_1_3_1_11_2","doi-asserted-by":"publisher","DOI":"10.1097\/IAE.0b013e3182618bab"},{"key":"e_1_3_1_12_2","doi-asserted-by":"publisher","DOI":"10.1136\/bjophthalmol-2014-305893"},{"key":"e_1_3_1_13_2","doi-asserted-by":"publisher","DOI":"10.1097\/ICB.0000000000000429"},{"key":"e_1_3_1_14_2","doi-asserted-by":"publisher","DOI":"10.3928\/15428877-20101031-03"},{"key":"e_1_3_1_15_2","doi-asserted-by":"publisher","DOI":"10.1002\/jca.20310"},{"key":"e_1_3_1_16_2","doi-asserted-by":"publisher","DOI":"10.1097\/ICB.0000000000000292"},{"key":"e_1_3_1_17_2","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2021.658407"},{"key":"e_1_3_1_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.exer.2019.04.006"},{"key":"e_1_3_1_19_2","doi-asserted-by":"publisher","DOI":"10.1080\/09273948.2020.1773867"},{"key":"e_1_3_1_20_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0749-0704(01)00010-0"}],"container-title":["Ophthalmic Surgery, Lasers and Imaging Retina"],"original-title":[],"language":"en","deposited":{"date-parts":[[2023,5,3]],"date-time":"2023-05-03T03:25:58Z","timestamp":1683084358000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.healio.com\/doi\/10.3928\/23258160-20220604-01"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,6]]},"references-count":19,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2022,6]]}},"alternative-id":["10.3928\/23258160-20220604-01"],"URL":"https:\/\/doi.org\/10.3928\/23258160-20220604-01","relation":{},"ISSN":["2325-8160","2325-8179"],"issn-type":[{"value":"2325-8160","type":"print"},{"value":"2325-8179","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,6]]}}}