{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T04:31:25Z","timestamp":1777955485890,"version":"3.51.4"},"reference-count":30,"publisher":"SLACK, Inc.","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Pediatr Ophthalmol Strabismus"],"published-print":{"date-parts":[[2022,7]]},"abstract":"\n Purpose:<\/jats:title>\n To evaluate the incidence and risk factors for retinopathy of prematurity (ROP) in two Portuguese neonatal units with a sub-analysis of infants with a gestational age (GA) of 28 weeks or older.<\/jats:p>\n <\/jats:sec>\n \n Methods:<\/jats:title>\n This was a retrospective case series of all infants who underwent ROP screening from 2012 to 2020. Demographic, clinical, and laboratory data were collected. Univariate logistic regression was used to examine the risk factors for ROP followed by multivariate regression.<\/jats:p>\n <\/jats:sec>\n \n Results:<\/jats:title>\n \n A total of 475 infants were included with a median GA of 30 weeks (range: 23 to 36 weeks) and a median birth weight of 1,229 grams (range: 408 to 2,620 grams). ROP was diagnosed in 113 infants (23.8%) and 29 (6.1%) were treated. In the multivariate analysis, GA and hyperglycemia were significantly associated with severe ROP (\n P<\/jats:italic>\n < .001). In the subgroup analysis of infants with a GA of 28 weeks or older, bronchopulmonary dysplasia, late-onset sepsis, and hyperglycemia were linked to severe ROP.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions:<\/jats:title>\n The incidence of ROP in the cohort falls within the range of other high-income countries. Hyperglycemia overpowered all of the other risk factors. Although rare, more mature infants are also at risk for severe ROP. Infants with older GA share the same group of risk factors, but bronchopulmonary dysplasia seems to play a greater role.<\/jats:p>\n \n \n [\n J Pediatr Ophthalmol Strabismus<\/jats:italic>\n . 2022;59(4):254\u2013260.]\n <\/jats:bold>\n <\/jats:p>\n <\/jats:sec>","DOI":"10.3928\/01913913-20220104-01","type":"journal-article","created":{"date-parts":[[2022,2,22]],"date-time":"2022-02-22T18:20:22Z","timestamp":1645554022000},"page":"254-260","source":"Crossref","is-referenced-by-count":7,"title":["Incidence and Risk Factors for Retinopathy of Prematurity in a Portuguese Cohort"],"prefix":"10.3928","volume":"59","author":[{"given":"Ana C.","family":"Almeida","sequence":"first","affiliation":[]},{"given":"Margarida","family":"Br\u00edzido","sequence":"additional","affiliation":[]},{"given":"Susana","family":"Teixeira","sequence":"additional","affiliation":[]},{"given":"Constan\u00e7a","family":"Coelho","sequence":"additional","affiliation":[]},{"given":"Lu\u00eds Miguel","family":"Borrego","sequence":"additional","affiliation":[]},{"given":"Miguel","family":"Correia","sequence":"additional","affiliation":[]}],"member":"2308","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(13)60178-6"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1136\/bjophthalmol-2016-310041"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2010-0090"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1053\/j.semperi.2019.05.008"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.survophthal.2018.04.002"},{"key":"e_1_3_2_7_2","first-page":"1","article-title":"Consenso cl\u00ednico: retinopatia da prematuridade","author":"Henriques G","year":"2014","unstructured":"Henriques G, Brito CST. Consenso cl\u00ednico: retinopatia da prematuridade. Sec\u00e7\u00e3o de Neonatologia, Sociedade Portuguesa de Pediatria. 2014:1\u201312.","journal-title":"Sec\u00e7\u00e3o de Neonatologia, Sociedade Portuguesa de Pediatria"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.123.7.991"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.121.12.1684"},{"issue":"3","key":"e_1_3_2_10_2","first-page":"199","article-title":"Resultados de 12 anos de rastreio da retinopatia da prematuridade no Hospital Pedro Hispano","volume":"37","author":"Vieira BC","year":"2013","unstructured":"Vieira BC, Nascimento M, Ribeiro I, Carvalho R, Martins JN. Resultados de 12 anos de rastreio da retinopatia da prematuridade no Hospital Pedro Hispano. Oftalmologia. 2013;37(3):199\u2013204.","journal-title":"Oftalmologia"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.20344\/amp.9130"},{"key":"e_1_3_2_12_2","first-page":"198","article-title":"Retinopathy of prematurity in a neonatal intensive care unit: experience of eight years","volume":"46","author":"Moinho RMS","year":"2015","unstructured":"Moinho RMS, Monteiro M, Mimoso G. Retinopathy of prematurity in a neonatal intensive care unit: experience of eight years. Acta Pediatrica Portuguesa. 2015;46:198\u2013204.","journal-title":"Acta Pediatrica Portuguesa"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.7363\/060122"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.48560\/rspo.18704"},{"issue":"1","key":"e_1_3_2_15_2","first-page":"30","article-title":"Application of the WINROP model in Retinopathy of Prematurity (ROP) screening in a Portuguese cohort of premature infants","volume":"78","author":"Malheiro L","year":"2019","unstructured":"Malheiro L, Falc\u00e3o I, Neiva L. Application of the WINROP model in Retinopathy of Prematurity (ROP) screening in a Portuguese cohort of premature infants. Rev Bras Oftalmol. 2019;78(1):30\u201336.","journal-title":"Rev Bras Oftalmol"},{"issue":"4","key":"e_1_3_2_16_2","article-title":"Retinopatia da Prematuri-dade\u2013Revis\u00e3o de Crit\u00e9rios de Rastreio","volume":"42","author":"Sampaio F","year":"2018","unstructured":"Sampaio F, Mota A, Lemos JA. 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