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Experimental data reported in the literature were used, corresponding to four trials of a human leukemia xenograft in BALB\/c female rats over a period of forty days. The models were fitted to the following growth dynamics: normal tumor growth, growth with exosomes, growth with Imatinib, and growth with exosomes-Imatinib mixture. For the proposed logistic growth model, it was determined that when using Imatinib treatment the growth rate is 0.93 (95% CrI: 84.33\u201399.64) slower and reduces the tumor volume to approximately 10% (95% CrI : 8.67\u201310.81). In the presence of exosome treatment, the growth rate is 0.83 (95% CrI: 1.52\u201316.59) faster and the tumor volume is expanded by 40% (95% CrI: 25.36\u201357.28). Finally, in the presence of Imatinib-exosomes mixture treatment, the growth rate is 0.82 (95% CrI: 76.87\u201388.51) slower and the tumor volume is reduced by 95% (95% CrI: 86.76\u201399.85). It is concluded that the presence of exosomes partially inactivates the effect of the Imatinib drug on tumor growth in a mouse xenograft model.<\/p><\/abstract><\/jats:p>","DOI":"10.3934\/mbe.2023864","type":"journal-article","created":{"date-parts":[[2023,10,24]],"date-time":"2023-10-24T10:52:52Z","timestamp":1698144772000},"page":"19504-19526","source":"Crossref","is-referenced-by-count":1,"title":["Bayesian analysis of the effect of exosomes in a mouse xenograft model of chronic myeloid leukemia"],"prefix":"10.3934","volume":"20","author":[{"given":"Rafael","family":"Mart\u00ednez-Fonseca","sequence":"first","affiliation":[{"name":"Facultad de Matem\u00e1ticas, Universidad Aut\u00f3noma de Guerrero, Ciudad Universitaria s\/n Chilpancingo, Guerrero, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cruz","family":"Vargas-De-Le\u00f3n","sequence":"additional","affiliation":[{"name":"Divisi\u00f3n de Investigaci\u00f3n, Hospital Ju\u00e1rez de Mexico, Ciudad de M\u00e9xico 07760, Mexico"},{"name":"Secci\u00f3n de Estudios de Posgrado, Escuela Superior de Medicina, Instituto Polit\u00e9cnico Nacional, Ciudad de Mexico 11340, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ram\u00f3n","family":"Reyes-Carreto","sequence":"additional","affiliation":[{"name":"Facultad de Matem\u00e1ticas, Universidad Aut\u00f3noma de Guerrero, Ciudad Universitaria s\/n Chilpancingo, Guerrero, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Flaviano","family":"God\u00ednez-Jaimes","sequence":"additional","affiliation":[{"name":"Facultad de Matem\u00e1ticas, Universidad Aut\u00f3noma de Guerrero, Ciudad Universitaria s\/n Chilpancingo, Guerrero, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2321","reference":[{"key":"key-10.3934\/mbe.2023864-1","unstructured":"National Cancer Institute, What Is Cancer?<\/i>, 2023. 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