{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,10]],"date-time":"2026-04-10T07:39:13Z","timestamp":1775806753409,"version":"3.50.1"},"reference-count":54,"publisher":"American Institute of Mathematical Sciences (AIMS)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2019]]},"DOI":"10.3934\/microbiol.2019.1.1","type":"journal-article","created":{"date-parts":[[2019,1,17]],"date-time":"2019-01-17T06:04:11Z","timestamp":1547705051000},"page":"1-18","source":"Crossref","is-referenced-by-count":14,"title":["Microbiome predictors of dysbiosis and VRE decolonization in patients with recurrent &lt;em&gt;C. difficile&lt;\/em&gt; infections in a multi-center retrospective study"],"prefix":"10.3934","volume":"5","author":[{"given":"Marina","family":"Santiago","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"1 Finch Therapeutics, 200 Inner Belt Rd, Somerville, MA 02143, USA","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lindsay","family":"Eysenbach","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jessica","family":"Allegretti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Olga","family":"Aroniadis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lawrence","family":"J. Brandt","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Monika","family":"Fischer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ari","family":"Grinspan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Colleen","family":"Kelly","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Casey","family":"Morrow","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martin","family":"Rodriguez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Majdi","family":"Osman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zain","family":"Kassam","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mark","family":"B. Smith","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sonia","family":"Timberlake","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"2 OpenBiome, 2067 Massachusetts Ave, Cambridge, MA 02140, USA","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"3 Division of Gastroenterology, Brigham and Women\u2019s Hospital, 75 Francis St, Boston, MA 02115, USA","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"4 Department of Medicine (Gastroenterology), Albert Einstein College of Medicine, 1300 Morris Park Ave, Bronx, NY 10461, USA","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"5 Division of Gastroenterology, Indiana University School of Medicine, 340 W. 10th St, Indianapolis, IN 46202, USA","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"6 Division of Gastroenterology, Icahn School of Medicine at Mount Sinai, 1 Gustave L. Levy Pl, New York, NY 10029, USA","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"7 Women\u2019s Medicine Collaborative, Brown Alpert Medial School, 222 Richmond St, Providence, RI 02903, USA","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"8 Department of Cell, Developmental, and Integrative Biology, University of Alabama at Birmingham, 1720 2nd Ave S, Birmingham, AL 35294, USA","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"9 Division of Infectious Diseases, University of Alabama at Birmingham School of Medicine, 1670 University Blvd, Birmingham, AL 35233, USA","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2321","reference":[{"key":"2","doi-asserted-by":"publisher","DOI":"10.1186\/s12916-018-1121-8","article-title":"Quantifying where human acquisition of antibiotic resistance occurs: a mathematical modelling study","author":"Knight GM, Costelloe C, Deeny SR, et al.","journal-title":"<em>BMC Med<\/em>"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.1403169","article-title":"No vacancy: how beneficial microbes cooperate with immunity to provide colonization resistance to pathogens","author":"Sassone-Corsi M, Raffatellu M","journal-title":"<em>J Immunol<\/em>"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.R116.752295","article-title":"Colonization resistance: the deconvolution of a complex trait","author":"Olsan EE, Byndloss MX, Faber F, et al.","journal-title":"<em>J Biol Chem<\/em>"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1093\/femspd\/ftw051","article-title":"Microbiota and pathogen 'pas de deux': setting up and breaking down barriers to intestinal infection","author":"McKenney ES, Kendall MM","journal-title":"<em>Pathog Dis<\/em>"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1038\/nature20557","article-title":"Microcins mediate competition among Enterobacteriaceae in the inflamed gut","author":"Sassone-Corsi M, Nuccio S, Liu H, et al.","journal-title":"<em>Nature<\/em>"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1038\/nature07250","article-title":"Vancomycin-resistant enterococci exploit antibiotic-induced innate immune deficits","author":"Brandl K, Plitas G, Mihu C, et al.","journal-title":"<em>Nature<\/em>"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-micro-091014-104115","article-title":"Interactions between the gastrointestinal microbiome and <em>Clostridium difficile<\/em>","author":"Theriot CM, Young VB","journal-title":"<em>Annu Rev Microbiol<\/em>"},{"key":"9","article-title":"Use of stool transplant to clear fecal colonization with carbapenem-resistant <em>Enterobacteraciae<\/em> (CRE): proof of concept","unstructured":"9.         Freedman A (2014) Use of stool transplant to clear fecal colonization with carbapenem-resistant <em>Enterobacteraciae<\/em> (CRE): proof of concept. IDWeek."},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1111\/1469-0691.12683","article-title":"Donor feces infusion for eradication of Extended Spectrum beta-Lactamase producing <em>Escherichia coli<\/em> in a patient with end stage renal disease","author":"Singh R, Nood E, Nieuwdorp, et al.","journal-title":"<em>Clin Microbiol Infec<\/em>"},{"key":"11","article-title":"Loss of vancomycin-resistant Enterococcus fecal dominance in an organ transplant patient with <em>Clostridium difficile<\/em> colitis after fecal microbiota transplant","unstructured":"11.     Stripling J, Kumar R, Baddley JW, et al. (2015) Loss of vancomycin-resistant Enterococcus fecal dominance in an organ transplant patient with <em>Clostridium difficile<\/em> colitis after fecal microbiota transplant. <em>Open Forum Infect Dis<\/em> 2: 1\u20134."},{"key":"12","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.00820-15","article-title":"Fecal microbiota transplantation and successful resolution of multidrug-resistant-organism colonization","author":"Crun-Cianfione N, Sullivan E, Gonzalo B","journal-title":"<em>J Clin Microbiol<\/em>"},{"key":"13","article-title":"Refractory <em>Clostridium difficile<\/em> infection cured with fecal microbiota transplantation in vancomycin-resistant Enterococcus colonized patient","unstructured":"13.     Jang M, An J, Jung S, et al. (2014) Refractory <em>Clostridium difficile<\/em> infection cured with fecal microbiota transplantation in vancomycin-resistant Enterococcus colonized patient. <em>Intest Res<\/em> 13: 80\u201384."},{"key":"14","article-title":"Vancomycin-resistant enterococcal (VRE) titers diminish among patients with recurrent <em>Clostridium difficile<\/em> infection after administration of SER-109, a novel microbiome agent","unstructured":"14.     Lombardo M (2015) Vancomycin-resistant enterococcal (VRE) titers diminish among patients with recurrent <em>Clostridium difficile<\/em> infection after administration of SER-109, a novel microbiome agent. IDWeek."},{"key":"15","doi-asserted-by":"publisher","DOI":"10.1007\/s00005-016-0387-9","article-title":"Fecal microbiota transplantation inhibits multidrug-resistant gut pathogens: preliminary report performed in an immunocompromised host","author":"Bili\u0144ski J, Grzesiowski P, Muszynski J, et al.","journal-title":"<em>Arch Immunol Ther Ex<\/em>"},{"key":"16","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhin.2015.02.013","article-title":"Faecal microbiota transplantation for stool decolonization of OXA-48 carbapenemase-producing <em>Klebsiella pneumoniae<\/em>","author":"Lagier J, Million M, Fournier P, et al.","journal-title":"<em>J Hosp Infect<\/em>"},{"key":"17","doi-asserted-by":"publisher","DOI":"10.1186\/s12879-015-0973-1","article-title":"Fecal microbiota transplantation restores dysbiosis in patients with methicillin resistant <em>Staphylococcus aureus<\/em> enterocolitis","author":"Wei Y, Gong J, Zhu W, et al.","journal-title":"<em>BMC Infect Dis<\/em>"},{"key":"18","article-title":"Clearance of vancomycin-resistant Enterococcus colonization with fecal microbiota transplantation among patients with recurrent <em>Clostridium difficile<\/em> infection","unstructured":"18.     Eysenbach L, Allegretti JR, Aroniadis O, et al. (2016) Clearance of vancomycin-resistant Enterococcus colonization with fecal microbiota transplantation among patients with recurrent <em>Clostridium difficile<\/em> infection. IDWeek."},{"key":"19","doi-asserted-by":"publisher","DOI":"10.1093\/ofid\/ofw133","article-title":"Clearance of vancomycin-resistant Enterococcus concomitant with administration of a microbiota-based drug targeted at recurrent <em>Clostridium difficile<\/em> infection","author":"Dubberke ER, Mullane KM, Gerding DN, et al.","journal-title":"<em>Open Forum Infect Dis<\/em>"},{"key":"20","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciw390","article-title":"Reduction of antibiotic resistance genes in intestinal microbiota of patients with recurrent <em>Clostridium difficile<\/em> infection after fecal microbiota transplantation","author":"Jouhten H, Mattila E, Arkkila P, et al.","journal-title":"<em>Clin Infect Dis<\/em>"},{"key":"21","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciw185","article-title":"Fecal microbial transplants reduce antibiotic-resistant genes in patients with recurrent <em>Clostridium difficile<\/em> infection","author":"Millan B, Park H, Hotte N, et al.","journal-title":"<em>Clin Infect Dis<\/em>"},{"key":"22","doi-asserted-by":"publisher","DOI":"10.1016\/j.diagmicrobio.2016.09.004","article-title":"Gut eradication of VIM-1 producing ST9 Klebsiella oxytoca after fecal microbiota transplantation for diarrhea caused by a <em>Clostridium difficile<\/em> hypervirulent R027 strain","author":"Garc\u00eda-Fern\u00e1ndez S, Morosini M, Cobo M, et al.","journal-title":"<em>Diagn Micr Infec Dis<\/em>"},{"key":"23","article-title":"Can fecal microbiota transplantation (FMT) eradicate fecal colonization with vancomycin-resistant Enterococci (VRE)","unstructured":"23.     Sohn KM, Cheon S, Kim YS (2016) Can fecal microbiota transplantation (FMT) eradicate fecal colonization with vancomycin-resistant Enterococci (VRE)? <em>Infect Cont Hosp Ep<\/em> 37: 1519\u20131521."},{"key":"24","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhin.2017.02.001","article-title":"Is faecal microbiota transplantation an option to eradicate highly drug-resistant enteric bacteria carriage","author":"Davido B, Batista R, Michelon H, et al.","journal-title":"<em>J Hosp Infect<\/em>"},{"key":"25","article-title":"Fecal microbiota transplantation: is there a role in the eradication of carbapenem-resistant <em>Klebsiella pneumoniae<\/em> intestinal carriage","unstructured":"25.     Ponte A, Pinho R, Mota M (2017) Fecal microbiota transplantation: is there a role in the eradication of carbapenem-resistant <em>Klebsiella pneumoniae<\/em> intestinal carriage? <em>Rev Esp Enferm Dig<\/em> 109: 392."},{"key":"26","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/cix252","article-title":"Fecal microbiota transplantation in patients with blood disorders inhibits gut colonization with antibiotic-resistant bacteria: results of a prospective, single-center study","author":"Bilinski J, Grzesiowski P, Sorensen N, et al.","journal-title":"<em>Clin Infect Dis<\/em>"},{"key":"27","doi-asserted-by":"publisher","DOI":"10.1016\/j.idcr.2018.e00432","article-title":"Fecal microbiota transplantation as a potential way to eradicate multiresistant microorganisms","author":"Dias C, Pipa S, Duarte-Ribeiro F, et al.","journal-title":"<em>IDCases<\/em>"},{"key":"28","doi-asserted-by":"publisher","DOI":"10.1017\/ice.2016.242","article-title":"Status of the prevention of multidrug-resistant organisms in international settings: a survey of the society for healthcare epidemiology of america research network","author":"Safdar N, Sengupta S, Musuuza JS, et al.","journal-title":"<em>Infect Cont Hosp Ep<\/em>"},{"key":"29","doi-asserted-by":"publisher","DOI":"10.7326\/M16-0271","article-title":"Effect of fecal microbiota transplantation on recurrence in multiply recurrent <em>Clostridium difficile<\/em> infection: a randomized trial","author":"Kelly CR, Khoruts A, Staley C, et al.","journal-title":"<em>Ann Intern Med<\/em>"},{"key":"30","doi-asserted-by":"publisher","DOI":"10.1128\/AEM.01043-13","article-title":"Development of a dual-index sequencing strategy and curation pipeline for analyzing amplicon sequence data on the MiSeq Illumina sequencing platform","author":"Kozich JJ, Westcott SL, Baxter NT, et al.","journal-title":"<em>Appl Environ Microb<\/em>"},{"key":"31","doi-asserted-by":"publisher","DOI":"10.1038\/nmeth.f.303","article-title":"QIIME allows analysis of high-throughput community sequencing data","author":"Caporaso JG, Kucznyski J, Stombaugh J, et al.","journal-title":"<em>Nat Method<\/em>s"},{"key":"32","article-title":"Intestinal domination and the risk of bacteremia in patients undergoing allogeneic hematopoietic stem cell transplantation","unstructured":"32.     Taur Y, Xavier J, Lipuma L, et al. (2012) Intestinal domination and the risk of bacteremia in patients undergoing allogeneic hematopoietic stem cell transplantation. <em>Clin Infect Dis<\/em> 5: 905\u2013914."},{"key":"33","doi-asserted-by":"publisher","DOI":"10.5694\/mja17.00295","article-title":"Faecal microbiota transplantation for <em>Clostridium difficile<\/em>-associated diarrhoea: a systematic review of randomised controlled trials","author":"Moayyedi P, Yuan Y, Baharith H, et al.","journal-title":"<em>Med J Aust<\/em>"},{"key":"34","article-title":"499 donor recruitment and eligibility for fecal microbiota transplantation: results from an international public stool bank","unstructured":"34.     Burns LJ, Dubois N, Smith MB, et al. (2015) 499 donor recruitment and eligibility for fecal microbiota transplantation: results from an international public stool bank. <em>Gastroenterology<\/em> 48: 96\u201397."},{"key":"35","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajic.2016.01.003","article-title":"Intestinal microbiome disruption in patients in a long-term acute care hospital: A case for development of microbiome disruption indices to improve infection prevention","author":"Halpin AL, de Man TJB, Kraft CS, et al.","journal-title":"<em>Am J Infect Control<\/em>"},{"key":"36","doi-asserted-by":"publisher","DOI":"10.1186\/s40168-018-0549-6","article-title":"Predicting recurrence of <em>Clostridium difficile<\/em> infection following encapsulated fecal microbiota transplantation","author":"Staley C, Kaiser T, Vaughn BP, et al.","journal-title":"<em>Microbiome<\/em>"},{"key":"37","doi-asserted-by":"publisher","DOI":"10.1086\/525047","article-title":"Decreased diversity of the fecal microbiome in recurrent <em>Clostridium difficile<\/em>-associated diarrhea","author":"Chang JY, Antonopoulos DA, Kaira A, et al.","journal-title":"<em>J Infect Dis<\/em>"},{"key":"38","doi-asserted-by":"publisher","DOI":"10.1038\/ismej.2014.13","article-title":"Reset of a critically disturbed microbial ecosystem: faecal transplant in recurrent <em>Clostridium difficile<\/em> infection","author":"Fuentes S, van Nood E, Tims S, et al.","journal-title":"<em>ISME J<\/em>"},{"key":"39","doi-asserted-by":"publisher","DOI":"10.1172\/JCI43918","article-title":"Vancomycin-resistant Enterococcus domination of intestinal microbiota is enabled by antibiotic treatment in mice and precedes bloodstream invasion in humans","author":"Ubeda C, Taur Y, Jenq R, et al.","journal-title":"<em>J Clin Invest<\/em>"},{"key":"40","article-title":"Enterococcus Diversity, Origins in Nature, and Gut Colonization, In: <em>Enterococci: From Commensals to Leading Causes of Drug Resistant Infection<\/em>, 4 Eds","unstructured":"40.     Lebreton F, Willems RJL, Gilmore MS (2014) Enterococcus Diversity, Origins in Nature, and Gut Colonization, In: <em>Enterococci: From Commensals to Leading Causes of Drug Resistant Infection<\/em>, 4 Eds., Boston: Massachusetts Eye and Ear Infirmary."},{"key":"41","article-title":"Determination of 16S rRNA sequences of Enterococci and application to species identification of nonmotile <em>Enterococcus gallinarum<\/em> isolates","unstructured":"41.     Patel R, Piper KE, Rouse MS, et al. (1998) Determination of 16S rRNA sequences of Enterococci and application to species identification of nonmotile <em>Enterococcus gallinarum<\/em> isolates. <em>J Clin Microbiol<\/em> 36: 3399\u20133407."},{"key":"42","doi-asserted-by":"publisher","DOI":"10.1038\/nature11234","article-title":"Structure, function and diversity of the healthy human microbiome","author":"Huttenhower C, Gevers D, Knight R, et al.","journal-title":"<em>Nature<\/em>"},{"key":"43","doi-asserted-by":"publisher","DOI":"10.1136\/gut.2006.099796","article-title":"High prevalence of <em>Escherichia coli<\/em> belonging to the B2+D phylogenetic group in inflammatory bowel disease","author":"Kotlowski R, Bernstein CN, Sepehri S, et al.","journal-title":"<em>Gut<\/em>"},{"key":"44","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.05496-11","article-title":"Profound alterations of intestinal microbiota following a single dose of clindamycin results in sustained susceptibility to <em>Clostridium difficile<\/em>-induced colitis","author":"Buffie CG, Jarchum I, Equinda M, et al.","journal-title":"<em>Infect Immun<\/em>"},{"key":"45","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2016.10.043","article-title":"A dietary fiber-deprived gut microbiota degrades the colonic mucus barrier and enhances pathogen susceptibility","author":"Desai MS, Seekatz AM, Koropatkin NM, et al.","journal-title":"<em>Cell<\/em>"},{"key":"46","article-title":"Microbiota metabolite short-chain fatty acid acetate promotes intestinal IgA response to microbiota which is mediated by GPR43","unstructured":"46.     Wu W, Sun M, Chen F, et al. (2016) Microbiota metabolite short-chain fatty acid acetate promotes intestinal IgA response to microbiota which is mediated by GPR43. <em>Mucosal Immunol<\/em> 10: 946\u2013956."},{"key":"47","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.1600165","article-title":"Diet-derived short chain fatty acids stimulate intestinal epithelial cells to induce mucosal tolerogenic dendritic cells","author":"Goverse G, Molenaar R, Maci L, et al.","journal-title":"<em>J Immunol<\/em>"},{"key":"48","doi-asserted-by":"publisher","DOI":"10.1016\/j.imlet.2014.04.014","article-title":"The impact of intestinal inflammation on the nutritional environment of the gut microbiota","author":"Faber F, B\u00e4umler AJ","journal-title":"<em>Immunol Lett<\/em>"},{"key":"49","article-title":"Phage-mediated acquisition of a type III secreted effector protein boosts growth of <em>Salmonella<\/em> by nitrate respiration","unstructured":"49.     Lopez CA, Winter SE, Rivera-Chavez F, et al. (2012) Phage-mediated acquisition of a type III secreted effector protein boosts growth of <em>Salmonella<\/em> by nitrate respiration. <em>Mbio<\/em> 3: e00143-12."},{"key":"50","article-title":"Host-derived nitrate boosts growth of <em>E","unstructured":"50.     Winter SE, Winter MG, Xavier MN, et al. (2013) Host-derived nitrate boosts growth of <em>E. coli<\/em> in the inflamed gut. <em>Science<\/em> 339: 708\u2013711."},{"key":"51","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1107857108","article-title":"Intestinal inflammation allows <em>Salmonella<\/em> to use ethanolamine to compete with the microbiota","author":"Thiennimitr P, Winter SE, Winter MG, et al.","journal-title":"<em>P Natl Acad Sci USA<\/em>"},{"key":"52","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajic.2010.10.024","article-title":"Implications for vancomycin-resistant Enterococcus colonization associated with <em>Clostridium difficile<\/em> infections","author":"Fujitani S, George WL, Morgan MA, et al.","journal-title":"<em>Am J Infect Control<\/em>"},{"key":"53","article-title":"Bacterial and fungal microbiota changes distinguish <em>C","unstructured":"53.     Sangster W, Hegarty JP, Schieffer KM, et al. (2016) Bacterial and fungal microbiota changes distinguish <em>C. difficile<\/em> infection from other forms of diarrhea: results of a prospective inpatient study. <em>Front Microbiol<\/em> 7: 789."},{"key":"54","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-017-15434-1","article-title":"Evaluating the effect of <em>Clostridium difficile<\/em> conditioned medium on fecal microbiota community structure","author":"Horvat S, Mahnic A, Breskvar M, et al.","journal-title":"<em>Sci Rep<\/em>"},{"key":"55","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0039242","article-title":"Non-invasive mapping of the gastrointestinal microbiota identifies children with inflammatory bowel disease","author":"Papa E, Docktor M, Smillie C, et al.","journal-title":"<em>PLoS One<\/em>"}],"container-title":["AIMS Microbiology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.aimspress.com\/article\/10.3934\/microbiol.2019.1.1","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,1,17]],"date-time":"2019-01-17T06:04:12Z","timestamp":1547705052000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.aimspress.com\/article\/10.3934\/microbiol.2019.1.1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019]]},"references-count":54,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2019]]}},"URL":"https:\/\/doi.org\/10.3934\/microbiol.2019.1.1","relation":{},"ISSN":["2471-1888"],"issn-type":[{"value":"2471-1888","type":"print"}],"subject":[],"published":{"date-parts":[[2019]]}}}