{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,4]],"date-time":"2026-07-04T21:01:04Z","timestamp":1783198864561,"version":"3.54.6"},"reference-count":68,"publisher":"American Institute of Mathematical Sciences (AIMS)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021]]},"DOI":"10.3934\/microbiol.2021014","type":"journal-article","created":{"date-parts":[[2021,6,15]],"date-time":"2021-06-15T04:02:12Z","timestamp":1623729732000},"page":"216-237","source":"Crossref","is-referenced-by-count":14,"title":["Effect of Nora virus infection on native gut bacterial communities of <i>Drosophila melanogaster<\/i>"],"prefix":"10.3934","volume":"7","author":[{"given":"Makayla","family":"Schissel","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"Biology Department, University of Nebraska at Kearney, 2401 11th<\/sup> Ave, Kearney, NE 68849, USA","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rebecca","family":"Best","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shelby","family":"Liesemeyer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuan-De","family":"Tan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Darby J.","family":"Carlson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julie J.","family":"Shaffer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nagavardhini","family":"Avuthu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chittibabu","family":"Guda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kimberly A.","family":"Carlson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"Department of Genetics, Cell Biology and Anatomy, University of Nebraska Medical Center, 985805 Nebraska Medical Center, Omaha, NE 68198-5805, USA","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2321","reference":[{"key":"key-10.3934\/microbiol.2021014-1","unstructured":"Gorbach SL (1996) Microbiology of the gastrointestinal tract. Medical Microbiology<\/i> Galveston: Universtity of Texax Medical Branch at Galveston."},{"key":"key-10.3934\/microbiol.2021014-2","doi-asserted-by":"crossref","unstructured":"Dantoft W, Lundin D, Esfahani SS, et al. (2016) The POU\/Oct transcription factor Pdm1\/nub is necessary for a beneficial gut microbiota and normal lifespan of Drosophila<\/i>. J Innate Immun<\/i> 8: 412-426.","DOI":"10.1159\/000446368"},{"key":"key-10.3934\/microbiol.2021014-3","doi-asserted-by":"crossref","unstructured":"Reiter LT, Potocki L, Chien S, et al. (2001) A systematic analysis of human disease-associated gene sequences in Drosophila melanogaster<\/i>. Genome Res<\/i> 11: 1114-1125.","DOI":"10.1101\/gr.169101"},{"key":"key-10.3934\/microbiol.2021014-4","doi-asserted-by":"crossref","unstructured":"Newell PD, Chaston JM, Wang Y, et al. (2014) In vivo<\/i> function and comparative genomic analyses of the Drosophila<\/i> gut microbiota identify candidate symbiosis factors. Front Microbiol<\/i> 5: 576.","DOI":"10.3389\/fmicb.2014.00576"},{"key":"key-10.3934\/microbiol.2021014-5","doi-asserted-by":"crossref","unstructured":"Strigini M, Leulier F (2016) The role of the microbial environment in Drosophila<\/i> post-embryonic development. Dev Comp Immunol<\/i> 64: 39-52.","DOI":"10.1016\/j.dci.2016.01.017"},{"key":"key-10.3934\/microbiol.2021014-6","doi-asserted-by":"crossref","unstructured":"Sommer AJ, Newell PD (2019) Metabolic basis for mutualism between gut bacteria and its impact on the Drosophila melanogaster<\/i> host. Appl Environ Micro<\/i> 85: e01182-18.","DOI":"10.1128\/AEM.01882-18"},{"key":"key-10.3934\/microbiol.2021014-7","doi-asserted-by":"crossref","unstructured":"Brummel T, Ching A, Seroude L, et al. (2004) Drosophila<\/i> lifespan enhancement by exogenous bacteria. Proc Natl Acad Sci<\/i> 101: 12974-12979.","DOI":"10.1073\/pnas.0405207101"},{"key":"key-10.3934\/microbiol.2021014-8","doi-asserted-by":"crossref","unstructured":"Storelli G, Defaye A, Erkosar B, et al. (2011) Lactobacillus plantarum<\/i> promotes drosophila systemic growth by modulating hormonal signals through TOR-dependent nutrient sensing. Cell Metab<\/i> 14: 403-414.","DOI":"10.1016\/j.cmet.2011.07.012"},{"key":"key-10.3934\/microbiol.2021014-9","doi-asserted-by":"crossref","unstructured":"Nehme NT, Li\u00e9geois S, Kele B, et al. (2007) A model of bacterial intestinal infections in Drosophila melanogaster<\/i>. PLoS Pathog<\/i> 3: e173.","DOI":"10.1371\/journal.ppat.0030173"},{"key":"key-10.3934\/microbiol.2021014-10","doi-asserted-by":"crossref","unstructured":"Fast D, Kostiuk B, Foley E, et al. (2018) Commensal pathogen competition impacts host viability. Proc Natl Acad Sci<\/i> 115: 7099-7104.","DOI":"10.1073\/pnas.1802165115"},{"key":"key-10.3934\/microbiol.2021014-11","doi-asserted-by":"crossref","unstructured":"Wong ACN, Vanhove AS, Watnick PI (2016) The interplay between intestinal bacteria and host metabolism in health and disease: Lessons from Drosophila melanogaster<\/i>. Dis Model Mech<\/i> 9: 271-281.","DOI":"10.1242\/dmm.023408"},{"key":"key-10.3934\/microbiol.2021014-12","doi-asserted-by":"crossref","unstructured":"Buchon N, Broderick NA, Chakrabarti S, et al. (2009) Invasive and indigenous microbiota impact intestinal stem cell activity through multiple pathways in Drosophila<\/i>. Genes Dev<\/i> 23: 2333-2344.","DOI":"10.1101\/gad.1827009"},{"key":"key-10.3934\/microbiol.2021014-13","doi-asserted-by":"crossref","unstructured":"Sharon G, Segal D, Ringo JM, et al. (2010) Commensal bacteria play a role in mating preference of Drosophila melanogaster<\/i>. Proc Natl Acad Sci<\/i> 107: 20051-20056.","DOI":"10.1073\/pnas.1009906107"},{"key":"key-10.3934\/microbiol.2021014-14","doi-asserted-by":"crossref","unstructured":"Xi Z, Ramirez JL, Dimopoulos G (2008) The Aedes aegypti<\/i> toll pathway controls Dengue virus infection. PLoS Pathog<\/i> 4: e1000098.","DOI":"10.1371\/journal.ppat.1000098"},{"key":"key-10.3934\/microbiol.2021014-15","doi-asserted-by":"crossref","unstructured":"Wu P, Sun P, Nie K, et al. (2019) A gut commensal bacterium promotes mosquito permissiveness to arboviruses. Cell Host Microbe<\/i> 25: 101-112.e5.","DOI":"10.1016\/j.chom.2018.11.004"},{"key":"key-10.3934\/microbiol.2021014-16","doi-asserted-by":"crossref","unstructured":"Barletta ABF, Nascimento-Silva MCL, Talyuli OAC, et al. (2017) Microbiota activates IMD pathway and limits Sindbis infection in Aedes aegypti<\/i>. Parasit Vectors<\/i> 10: 103.","DOI":"10.1186\/s13071-017-2040-9"},{"key":"key-10.3934\/microbiol.2021014-17","doi-asserted-by":"crossref","unstructured":"Carissimo G, Pondeville E, McFarlane M, et al. (2015) Antiviral immunity of Anopheles gambiae is highly compartmentalized, with distinct roles for RNA interference and gut microbiota. Proc Natl Acad Sci<\/i> 112: E176-E185.","DOI":"10.1073\/pnas.1412984112"},{"key":"key-10.3934\/microbiol.2021014-18","doi-asserted-by":"crossref","unstructured":"Sansone CL, Cohen J, Yasunga A, et al. (2015) Microbiota-dependent priming of antiviral intestinal immunity in Drosophila<\/i>. Cell Host Microbe<\/i> 18: 571-581.","DOI":"10.1016\/j.chom.2015.10.010"},{"key":"key-10.3934\/microbiol.2021014-19","doi-asserted-by":"crossref","unstructured":"Franchini A, Mandrioli M, Franceschi C, et al. (2012) Morpho-functional changes of fat body in bacteria fed Drosophila melanogaster<\/i> strains. J Mol Hist<\/i> 43: 243-251.","DOI":"10.1007\/s10735-011-9382-y"},{"key":"key-10.3934\/microbiol.2021014-20","doi-asserted-by":"crossref","unstructured":"Shi J, Song Y, Shentu X, et al. (2021) Anitmicrobials affect the fat body microbiome and increase the brown planthopper mortality. Front Microbiol<\/i> 12: 644897.","DOI":"10.3389\/fphys.2021.644897"},{"key":"key-10.3934\/microbiol.2021014-21","doi-asserted-by":"crossref","unstructured":"Nelson AM, Elftman MD, Pinto AK, et al. (2013) Murine norovirus infection does not cause major disruptions in the murine intestinal microbiota. Microbiome<\/i> 1: 17.","DOI":"10.1186\/2049-2618-1-7"},{"key":"key-10.3934\/microbiol.2021014-22","doi-asserted-by":"crossref","unstructured":"Sartor RB, Wu GD (2017) Roles for intestinal bacteria, viruses, and fungi in pathogenesis of inflammatory bowel diseases and therapeutic approaches. Gastroenterol<\/i> 152: 327-339.","DOI":"10.1053\/j.gastro.2016.10.012"},{"key":"key-10.3934\/microbiol.2021014-23","unstructured":"Munn B, Ericson B, Carlson DJ, et al. (2015) Detecting the presence of Nora virus in Drosophila<\/i> utilizing single fly RT-PCR. Bioscene<\/i> 41: 40-44."},{"key":"key-10.3934\/microbiol.2021014-24","doi-asserted-by":"crossref","unstructured":"Ekstr\u00f6m JO, Habayeb MS, Srivastava V, et al. (2011) Drosophila<\/i> Nora virus capsid proteins differ from those of other picorna-like viruses. Virus Res<\/i> 160: 51-58.","DOI":"10.1016\/j.virusres.2011.05.006"},{"key":"key-10.3934\/microbiol.2021014-25","doi-asserted-by":"crossref","unstructured":"Habayeb MS, Ekengren SK, Hultmark D (2006) Nora virus, a persistent virus in Drosophila<\/i>, defines a new picorna-like virus family. J Gen Virol<\/i> 87: 3045-3051.","DOI":"10.1099\/vir.0.81997-0"},{"key":"key-10.3934\/microbiol.2021014-26","doi-asserted-by":"crossref","unstructured":"Habayeb MS, Cantera R, Casanova G, et al. (2009) The Drosophila<\/i> Nora virus is an enteric virus, transmitted via feces. J Invertebr Pathol<\/i> 101: 29-33.","DOI":"10.1016\/j.jip.2009.02.003"},{"key":"key-10.3934\/microbiol.2021014-27","doi-asserted-by":"crossref","unstructured":"Rogers A, Towery L, McCown A, et al. (2020) Impaired geotaxis as a novel phenotype of Nora virus infection of Drosophila melanogaster<\/i>. Scientifica<\/i> 2020: Article ID 1804510.","DOI":"10.1155\/2020\/1804510"},{"key":"key-10.3934\/microbiol.2021014-28","doi-asserted-by":"crossref","unstructured":"Karst SM (2016) The influence of commensal bacteria on infection with enteric viruses. Nat Rev Microbiol<\/i> 14: 197-204.","DOI":"10.1038\/nrmicro.2015.25"},{"key":"key-10.3934\/microbiol.2021014-29","doi-asserted-by":"crossref","unstructured":"Cordes EJ, Licking-Murray KD, Carlson KA (2013) Differential gene expression related to Nora virus infection of Drosophila melanogaster<\/i>. Virus Res<\/i> 175: 95-100.","DOI":"10.1016\/j.virusres.2013.03.021"},{"key":"key-10.3934\/microbiol.2021014-30","doi-asserted-by":"crossref","unstructured":"Hedengren M, Asling B, Dushay MS, et al. (1999) Relish<\/i>, a central factor in the control of humoral but not cellular immunity in Drosophila<\/i>. Mol Cell<\/i> 4: 827-837.","DOI":"10.1016\/S1097-2765(00)80392-5"},{"key":"key-10.3934\/microbiol.2021014-31","doi-asserted-by":"crossref","unstructured":"Caporaso JG, Kuczynski J, Stombaugh J, et al. (2010) QIIME allows analysis of high-throughput community sequencing data. Nat Methods<\/i> 7: 335-336.","DOI":"10.1038\/nmeth.f.303"},{"key":"key-10.3934\/microbiol.2021014-32","doi-asserted-by":"crossref","unstructured":"Callahan BJ, McMurdie PJ, Rosen MJ, et al. (2016) DADA2: High-resolution sample inference from Illumina amplicon data. Nat Methods<\/i> 13: 581-583.","DOI":"10.1038\/nmeth.3869"},{"key":"key-10.3934\/microbiol.2021014-33","doi-asserted-by":"crossref","unstructured":"Bokulich NA, Subramanian S, Faith JJ, et al. (2013) Quality-filtering vastly improves diversity estimates from Illumina amplicon sequencing. Nat Methods<\/i> 10: 57-59.","DOI":"10.1038\/nmeth.2276"},{"key":"key-10.3934\/microbiol.2021014-34","doi-asserted-by":"crossref","unstructured":"Spellerberg IF, Fedor PJ (2003) A tribute to Claude-Shannon (1916-2001) and a plea for more rigorous use of species richness, species diversity and the \u2018Shannon-Wiener\u2019 Index. Glob Ecol Biogeogr<\/i> 12: 177-179.","DOI":"10.1046\/j.1466-822X.2003.00015.x"},{"key":"key-10.3934\/microbiol.2021014-35","doi-asserted-by":"crossref","unstructured":"Pielou EC (1981) The usefulness of ecological models: A stock-taking. Q Rev Biol<\/i> 56: 17-31.","DOI":"10.1086\/412081"},{"key":"key-10.3934\/microbiol.2021014-36","doi-asserted-by":"crossref","unstructured":"Mulder CPH, Bazeley-White E, Dimitrakopoulos PG, et al. (2004) Species evenness and productivity in experimental plant communities. Oikos<\/i> 107: 50-63.","DOI":"10.1111\/j.0030-1299.2004.13110.x"},{"key":"key-10.3934\/microbiol.2021014-37","doi-asserted-by":"crossref","unstructured":"Faith DP (1992) Conservation evaluation and phylogenetic diversity. Biol Conserv<\/i> 61: 1-10.","DOI":"10.1016\/0006-3207(92)91201-3"},{"key":"key-10.3934\/microbiol.2021014-38","doi-asserted-by":"crossref","unstructured":"Lozupone C, Knight R (2005) UniFrac: A new phylogenetic method for comparing microbial communities. Appl Environ Microbiol<\/i> 71: 8228-8235.","DOI":"10.1128\/AEM.71.12.8228-8235.2005"},{"key":"key-10.3934\/microbiol.2021014-39","unstructured":"Sultan R, Stampas A, Goldberg MB, et al. (2001) Drug resistance of bacteria commensal with Drosophila melanogaster<\/i> in laboratory cultures. Dros Inf Serv<\/i> 84: 175-180."},{"key":"key-10.3934\/microbiol.2021014-40","doi-asserted-by":"crossref","unstructured":"Kernbauer E, Ding Y, Cadwell K (2014) An enteric virus can replace the beneficial function of commensal bacteria. Nature<\/i> 516: 94-98.","DOI":"10.1038\/nature13960"},{"key":"key-10.3934\/microbiol.2021014-41","doi-asserted-by":"crossref","unstructured":"Johnson KN, Christian PD (1998) The novel genome organization of the insect picorna-like virus Drosophila C virus suggests this virus belongs to a previously undescribed virus family. J Gen Virol<\/i> 79: 191-203.","DOI":"10.1099\/0022-1317-79-1-191"},{"key":"key-10.3934\/microbiol.2021014-42","doi-asserted-by":"crossref","unstructured":"Arnold PA, Johnson KN, White CR (2013) Physiological and metabolic consequences of viral infection in Drosophila melanogaster. J Exp Biol<\/i> 216: 3350-3357.","DOI":"10.1242\/jeb.088138"},{"key":"key-10.3934\/microbiol.2021014-43","doi-asserted-by":"crossref","unstructured":"Rozas-Dennis GS, Cazzaniga NJ (2000) Effects of Triatoma virus (TrV) on the fecundity and moulting of Triatoma infestans<\/i> (Hemiptera: Reduviidae). Ann Trop Med Parasitol<\/i> 94: 633-641.","DOI":"10.1080\/00034983.2000.11813586"},{"key":"key-10.3934\/microbiol.2021014-44","doi-asserted-by":"crossref","unstructured":"Clark RI, Salazar A, Yamada R, et al. (2015) Distinct shifts in microbiota composition during Drosophila<\/i> aging impair intestinal function and drive mortality. Cell Rep<\/i> 12: 1656-1667.","DOI":"10.1016\/j.celrep.2015.08.004"},{"key":"key-10.3934\/microbiol.2021014-45","doi-asserted-by":"crossref","unstructured":"Petkau K, Parsons BD, Duggal A, et al. (2014) A deregulated intestinal cell cycle program disrupts tissue homeostasis without affecting longevity in Drosophila<\/i>. J Biol Chem<\/i> 289: 28719-29.","DOI":"10.1074\/jbc.M114.578708"},{"key":"key-10.3934\/microbiol.2021014-46","doi-asserted-by":"crossref","unstructured":"Yamada R, Deshpande SA, Bruce KD, et al. (2015) Microbes promote amino acid harvest to rescue undernutrition in Drosophila<\/i>. Cell Rep<\/i> 10: 865-72.","DOI":"10.1016\/j.celrep.2015.01.018"},{"key":"key-10.3934\/microbiol.2021014-47","doi-asserted-by":"crossref","unstructured":"Galenza A, Hutchinson J, Campbell SD, et al. (2016) Glucose modulates Drosophila<\/i> longevity and immunity independent of the microbiota. Biol Open<\/i> 5: 165-73.","DOI":"10.1242\/bio.015016"},{"key":"key-10.3934\/microbiol.2021014-48","doi-asserted-by":"crossref","unstructured":"T\u00e9fit MA, Leulier F (2017) Lactobacillus plantarum<\/i> favors the early emergence of fit and fertile adult Drosophila<\/i> upon chronic undernutrition. J Exp Biol<\/i> 220: 900-07.","DOI":"10.1242\/jeb.151522"},{"key":"key-10.3934\/microbiol.2021014-49","doi-asserted-by":"crossref","unstructured":"Obata F, Fons CO, Gould AP (2018) Early-life exposure to low-dose oxidants can increase longevity via microbiome remodelling in Drosophila<\/i>. Nat Commun<\/i> 9: 975.","DOI":"10.1038\/s41467-018-03070-w"},{"key":"key-10.3934\/microbiol.2021014-50","doi-asserted-by":"crossref","unstructured":"Ren C, Webster P, Finkel SE, et al. (2007) Increased internal and external bacterial load during Drosophila<\/i> aging without life-span trade-off. Cell Metab<\/i> 6: 144-152.","DOI":"10.1016\/j.cmet.2007.06.006"},{"key":"key-10.3934\/microbiol.2021014-51","doi-asserted-by":"crossref","unstructured":"Matsumoto M, Kurihara S, Kibe R, et al. (2011) Longevity in mice is promoted by probiotic-induced suppression of colonic senescence dependent on upregulation of gut bacterial polyamine production. PLoS One<\/i> 6: e23652.","DOI":"10.1371\/journal.pone.0023652"},{"key":"key-10.3934\/microbiol.2021014-52","doi-asserted-by":"crossref","unstructured":"Erkosar B, Leulier F (2014) Transient adult microbiota, gut homeostasis and longevity: Novel insights from the Drosophila<\/i> model. FEBS Letters<\/i> 588: 4250-4257.","DOI":"10.1016\/j.febslet.2014.06.041"},{"key":"key-10.3934\/microbiol.2021014-53","doi-asserted-by":"crossref","unstructured":"Han G, Lee HJ, Jeong SE, et al. (2017) Comparative analysis of Drosophila melanogaster<\/i> gut microbiota with respect to host strain, sex, and age. Microb Ecol<\/i> 74: 207-216.","DOI":"10.1007\/s00248-016-0925-3"},{"key":"key-10.3934\/microbiol.2021014-54","doi-asserted-by":"crossref","unstructured":"Grandison RC, Wong R, Bass TM, et al. (2009) Effect of standardized dietary restriction protocol on multiple laboratory strains of Drosophila melanogaster<\/i>. PLoS One<\/i> 4: e4067.","DOI":"10.1371\/journal.pone.0004067"},{"key":"key-10.3934\/microbiol.2021014-55","doi-asserted-by":"crossref","unstructured":"Lee HY, Lee SH, Lee JH, et al. (2019) The role of commensal microbes in the lifespan of Drosophila melanogaster<\/i>. Aging<\/i> 11: 4611-4640.","DOI":"10.18632\/aging.102073"},{"key":"key-10.3934\/microbiol.2021014-56","doi-asserted-by":"crossref","unstructured":"Wong CN, Ng P, Douglas AE (2011) Low-diversity bacterial community in the gut of the fruitfly. Env Microbiol<\/i> 13: 1889-1900.","DOI":"10.1111\/j.1462-2920.2011.02511.x"},{"key":"key-10.3934\/microbiol.2021014-57","doi-asserted-by":"crossref","unstructured":"Dang AT, Cotton S, Sankaran-Walters S, et al. (2012) Evidence of an increased pathogenic footprint in the lingual microbiome of untreated HIV infected patients. BMC Microbiol<\/i> 12: 1-10.","DOI":"10.1186\/1471-2180-12-153"},{"key":"key-10.3934\/microbiol.2021014-58","doi-asserted-by":"crossref","unstructured":"Manna S, Baindara P, Mandal SM (2020) Molecular pathogenesis of secondary bacterial infection associated to viral infections including SARS-CoV-2. J Infect Public Health<\/i> 13: 1397-1404.","DOI":"10.1016\/j.jiph.2020.07.003"},{"key":"key-10.3934\/microbiol.2021014-59","unstructured":"Smith H, Sweet C (2002) Cooperation between viral and bacterial pathogens in causing human respiratory disease. Polymicrobial Diseases<\/i> Washington: ASM Press."},{"key":"key-10.3934\/microbiol.2021014-60","doi-asserted-by":"crossref","unstructured":"Malacrin\u00f2 A, Campolo O, Medina RF, et al. (2018) Instar- and host-associated differentiation of bacterial communities in the Mediterranean fruit fly Ceratitis capitata. PLoS One<\/i> 13: e0194131.","DOI":"10.1371\/journal.pone.0194131"},{"key":"key-10.3934\/microbiol.2021014-61","doi-asserted-by":"crossref","unstructured":"Gontang EA, Aylward FO, Carlos C, et al. (2017) Major changes in microbial diversity and community composition across gut sections of a juvenile Panchlora cockroach. PLoS One<\/i> 12: e0177189.","DOI":"10.1371\/journal.pone.0177189"},{"key":"key-10.3934\/microbiol.2021014-62","doi-asserted-by":"crossref","unstructured":"Miguel-Aliaga I, Jasper H, Lemaitre B (2018) Anatomy and physiology of the digestive tract of Drosophila melanogaster<\/i>. Genet<\/i> 210: 357-396.","DOI":"10.1534\/genetics.118.300224"},{"key":"key-10.3934\/microbiol.2021014-63","doi-asserted-by":"crossref","unstructured":"Cohen E, Sawyer JK, Peterson NG, et al. (2020) Physiology, development, and disease modeling in the Drosophila<\/i> excretory system. Genet<\/i> 214: 235-264.","DOI":"10.1534\/genetics.119.302289"},{"key":"key-10.3934\/microbiol.2021014-64","doi-asserted-by":"crossref","unstructured":"Zhang Y, Yongmei X (2014) Fat body development and its function in energy storage and nutrient sensing in Drosophila melanogaster<\/i>. J Tissue Sci Eng<\/i> 6: 1.","DOI":"10.4172\/2157-7552.1000141"},{"key":"key-10.3934\/microbiol.2021014-65","doi-asserted-by":"crossref","unstructured":"Chandler JA, Lang J, Bhatnagar S, et al. (2011) Bacterial communities of diverse Drosophila<\/i> species: Ecological context of a host-microbe model system. PLoS Genet<\/i> 7: e1002272.","DOI":"10.1371\/journal.pgen.1002272"},{"key":"key-10.3934\/microbiol.2021014-66","doi-asserted-by":"crossref","unstructured":"Jones RM, Luo L, Ardita CS, et al. (2013) Symbiotic lactobacilli stimulate gut epithelial proliferation via Nox-mediated generation of reactive oxygen species. EMBO J<\/i> 32: 3017-3028.","DOI":"10.1038\/emboj.2013.224"},{"key":"key-10.3934\/microbiol.2021014-67","doi-asserted-by":"crossref","unstructured":"Saxena D, Li Y, Yang L, et al. (2012) Human microbiome and HIV\/AIDS. Curr HIV\/AIDS Rep<\/i> 9: 44-51.","DOI":"10.1007\/s11904-011-0103-7"},{"key":"key-10.3934\/microbiol.2021014-68","doi-asserted-by":"crossref","unstructured":"Jones MK, Watanabe M, Zhu S, et al. (2014) Enteric bacteria promote human and mouse norovirus infection of B Cells. Science<\/i> 346: 755-759.","DOI":"10.1126\/science.1257147"}],"container-title":["AIMS Microbiology"],"original-title":[],"link":[{"URL":"http:\/\/www.aimspress.com\/article\/doi\/10.3934\/microbiol.2021014?viewType=html","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,6,15]],"date-time":"2021-06-15T04:04:05Z","timestamp":1623729845000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.aimspress.com\/article\/doi\/10.3934\/microbiol.2021014"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021]]},"references-count":68,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2021]]}},"URL":"https:\/\/doi.org\/10.3934\/microbiol.2021014","relation":{},"ISSN":["2471-1888"],"issn-type":[{"value":"2471-1888","type":"print"}],"subject":[],"published":{"date-parts":[[2021]]}}}