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When the null hypothesis of equality of curves is rejected, leading to the clear conclusion that at least one curve is different, we may assume that individuals can be grouped into a number of classes whose members all share the same regression function. We propose a method that allows determining such groups with an automatic selection of their number by means of bootstrapping. The validity and behavior of the proposed method were evaluated through simulation studies. The applicability of the proposed method is illustrated using real data from an experimental study in neurology.&lt;\/p&gt;&lt;\/abstract&gt;<\/jats:p>","DOI":"10.3934\/mbe.2022302","type":"journal-article","created":{"date-parts":[[2022,4,24]],"date-time":"2022-04-24T10:28:58Z","timestamp":1650796138000},"page":"6435-6454","source":"Crossref","is-referenced-by-count":0,"title":["A method for determining groups in nonparametric regression curves: Application to prefrontal cortex neural activity analysis"],"prefix":"10.3934","volume":"19","author":[{"given":"Javier","family":"Roca-Pardi\u00f1as","sequence":"first","affiliation":[{"name":"Department of Statistics and Operational Research, Vigo University, Vigo 36310, Spain"}]},{"given":"Celestino","family":"Ord\u00f3\u00f1ez","sequence":"additional","affiliation":[{"name":"Department of Mining Exploitation and Prospecting, Geomatics and Computer Graphics Lab, Oviedo University, Mieres 33600, Spain"}]},{"given":"Lu\u00eds Meira","family":"Machado","sequence":"additional","affiliation":[{"name":"Center of Mathematics, Minho University, Braga 4704-553, Portugal"}]}],"member":"2321","reference":[{"key":"key-10.3934\/mbe.2022302-1","unstructured":"P. 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