{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,13]],"date-time":"2026-05-13T05:18:03Z","timestamp":1778649483722,"version":"3.51.4"},"reference-count":0,"publisher":"AVES YAYINCILIK A.\u015e.","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["AOTT"],"abstract":"<jats:p>Abstract\n\nObjectives: We evaluated the inflammatory reactions induced by three commonly used nonabsorbable suture materials in a rabbit model.\\r\\nMethods: Three suture materials were tested: braided polyester suture (Ethibond), braided blend of polyester and polyethylene suture (FiberWire), and monofilament polypropylene suture (Polypropylene). Thirty-six rabbits were randomly allocated to three suture groups, equal in number. Each suture type was placed bilaterally in the quadriceps muscle, patellar tendon, knee joint capsule, and Achilles tendon. Six animals in each group were sacrificed in the third and sixth weeks. The inflammation induced by each suture was assessed using light microscopy and the width of the inflammation zone (WIZ) was measured.\\r\\nResults: Ethibond was found to cause the most severe reaction in the muscle and tendon in the third week; in the sixth week, however, it showed the lowest inflammatory reaction in all tissue types. Reaction to Propylene was moderate in the third week, whereas it caused the largest WIZ in all tissue types in the sixth week, such that the eventual size of the WIZ induced by Propylene (6.6\u00b12.1 mm) was significantly greater than that of Ethibond (1.6\u00b10.9 mm) in muscle specimens (p&lt;0.05). Except for the largest WIZ seen in joint capsule specimens in the third week, inflammatory reactions associated with FiberWire were low or moderate in all tissue specimens throughout the study. FiberWire was associated with some necrotic areas in two muscle and one tendon specimens. \\r\\nConclusion: The extent of inflammatory reaction to nonabsorbable suture materials depends on the type of suture material, tissue type, and the duration of postoperative time.\n\n\n\u00d6zet\n\nAma\u00e7: S\u0131k kullan\u0131lan \u00fc\u00e7 emilmeyen diki\u015f malzemesinin dokuda olu\u015fturdu\u011fu enflamatuvar yan\u0131tlar tav\u015fan modelinde de\u011ferlendirildi.\\r\\n\u00c7al\u0131\u015fma plan\u0131: \u00c7al\u0131\u015fmada, \u00f6rg\u00fcl\u00fc polyester (Ethibond), monofilaman polipropilen (Polypropylene) ve \u00f6rg\u00fcl\u00fc polietilen ve polyester kar\u0131\u015f\u0131m\u0131 (FiberWire) diki\u015f malzemesi kullan\u0131ld\u0131. Otuz alt\u0131 adet tav\u015fan, kullan\u0131lan diki\u015f materyaline g\u00f6re, e\u015fit say\u0131da \u00fc\u00e7 gruba ayr\u0131ld\u0131. Her bir diki\u015f malzemesi tav\u015fan\u0131n her iki baca\u011f\u0131ndaki kuadriseps kas\u0131na, patellar tendona, diz eklem kaps\u00fcl\u00fcne ve A\u015fil tendonuna uyguland\u0131. Her gruptaki alt\u0131\u015far tav\u015fan \u00fc\u00e7\u00fcnc\u00fc ve alt\u0131nc\u0131 haftalarda \u00f6ld\u00fcr\u00fcld\u00fc. Diki\u015f malzemesinin olu\u015fturdu\u011fu enflamatuvar yan\u0131t \u0131\u015f\u0131k mikroskobu kullan\u0131larak de\u011ferlendirildi ve enflamatuvar alan\u0131n geni\u015fli\u011fi \u00f6l\u00e7\u00fcld\u00fc.\\r\\nSonu\u00e7lar: \u00dc\u00e7\u00fcnc\u00fc haftada kas ve tendonda en \u015fiddetli enflamatuvar yan\u0131t\u0131 Ethibond olu\u015ftururken, Ethibond\u2019a ba\u011fl\u0131 yan\u0131t alt\u0131nc\u0131 haftada t\u00fcm dokularda en az d\u00fczeydeydi. \u00dc\u00e7\u00fcnc\u00fc haftada Propilen\u2019in olu\u015fturdu\u011fu yan\u0131t orta d\u00fczeyde iken, alt\u0131nc\u0131 haftada t\u00fcm dokularda en geni\u015f enflamatuvar alana sahipti. Alt\u0131nc\u0131 haftada kasta Propilen\u2019in olu\u015fturdu\u011fu enflamatuvar alan geni\u015fli\u011fi (6.6\u00b12.1 mm) Ethibond\u2019un olu\u015fturdu\u011fundan (1.6\u00b10.9 mm) anlaml\u0131 derecede fazlayd\u0131 (p&lt;0.05). FiberWire \u00fc\u00e7\u00fcnc\u00fc haftada eklem kaps\u00fcl\u00fcnde en geni\u015f enflamatuvar yan\u0131t\u0131 olu\u015fturdu, fakat di\u011fer dokularda \u00fc\u00e7\u00fcnc\u00fc ve alt\u0131nc\u0131 haftalarda olu\u015fan enflamatuvar yan\u0131t d\u00fc\u015f\u00fck veya orta d\u00fczeydeydi. \u0130ki kas ve bir tendon \u00f6rne\u011finde FiberWire\u2019a ba\u011fl\u0131 baz\u0131 nekrotik alanlar g\u00f6r\u00fcld\u00fc.\\r\\n\u00c7\u0131kar\u0131mlar: Emilmeyen diki\u015f malzemelerine kar\u015f\u0131 olu\u015fan enflamatuvar yan\u0131t, materyalin cinsine, doku tipine ve ameliyat sonras\u0131 ge\u00e7en s\u00fcreye ba\u011fl\u0131d\u0131r.<\/jats:p>","DOI":"10.3944\/aott.2009.366","type":"journal-article","created":{"date-parts":[[2009,10,1]],"date-time":"2009-10-01T07:42:43Z","timestamp":1254382963000},"page":"366-372","source":"Crossref","is-referenced-by-count":36,"title":["Evaluation of soft tissue reactions to three nonabsorbable suture materials in a rabbit model"],"prefix":"10.5152","volume":"43","author":[{"given":"Cem","family":"Zeki Esenyel","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mehmet","family":"Demirhan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Onder","family":"Kilicoglu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Oktay","family":"Adanir","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bilge","family":"Bilgic","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ozlem","family":"Guzel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Serhat","family":"Ozsoy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"3111","published-online":{"date-parts":[[2020,2,8]]},"container-title":["Acta Orthopaedica et Traumatologica Turcica"],"original-title":[],"link":[{"URL":"https:\/\/aott.org.tr\/index.php\/pub\/article\/download\/2296\/2253","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,18]],"date-time":"2025-11-18T10:57:24Z","timestamp":1763463444000},"score":1,"resource":{"primary":{"URL":"https:\/\/aott.org.tr\/index.php\/pub\/article\/view\/2296"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,2,8]]},"references-count":0,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2009,1,4]]}},"URL":"https:\/\/doi.org\/10.3944\/aott.2009.366","relation":{},"ISSN":["2589-1294","1017-995X"],"issn-type":[{"value":"2589-1294","type":"electronic"},{"value":"1017-995X","type":"print"}],"subject":[],"published":{"date-parts":[[2020,2,8]]}}}