{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,27]],"date-time":"2026-01-27T11:44:19Z","timestamp":1769514259821,"version":"3.49.0"},"reference-count":0,"publisher":"AVES YAYINCILIK A.\u015e.","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["AOTT"],"abstract":"<jats:p>Abstract\n\nObjective: The aim of this study was to detect the incidence of estrogen receptors in human hip joint capsule and ligamentum teres. \\r\\nMethods: The study included biopsies of the ligamentum capitis femoris (LCF) and hip joint capsule from 15 patients undergoing hip surgery for developmental dysplasia of the hip (DDH) and from the control hips of 15 cases of intrauterine fetal death. Mean age was 10.3 (range: 6 to 18) months at the time of surgery. Full-thickness 1x1 cm anterior capsule and LCF portions were taken as biopsy specimens. An immunohistochemical study using monoclonal antibody against estrogen receptors was performed to identify the rate of target estrogen cells in the hip joint capsule and LCF. \\r\\nResults: Estrogen receptor (ER) staining rates were 1.6\u00b10.2% for the LCF and 1.3\u00b10.2% for the hip joint capsule in the control groups, and 2.5\u00b10.3% for the LCF and 2.0\u00b10.3% for the hip joint capsule in the DDH groups. Estrogen receptor staining rates in the LCF and hip joint capsule control groups were significantly lower than that in the DDH groups (p&lt;0.001). In both groups, ER rates were significantly lower in the hip joint capsule than in the LCF (p&lt;0.01).\\r\\nConclusion: The high rate of ERs in the LCF and hip joint capsule appears to support the effect of estrogen in the etiology of the DDH.\n\n\n\u00d6zet\n\nAma\u00e7: \u00c7al\u0131\u015fmam\u0131z\u0131n amac\u0131 insan kal\u00e7a eklem kaps\u00fcl\u00fc ve ligamentum capitis femorislerindeki \u00f6strojen resept\u00f6r\u00fc varl\u0131\u011f\u0131n\u0131 saptamakt\u0131.\\r\\n\u00c7al\u0131\u015fma plan\u0131: Geli\u015fimsel kal\u00e7a displazisi (GKD) nedeniyle ameliyat edilen 15 hastan\u0131n ve kontrol grubu olarak da 15 intrauterin \u00f6l\u00fc fet\u00fcs\u00fcn toplam 30 kal\u00e7as\u0131ndan ligamentum capitis femoris (LCF) ve kal\u00e7a eklem kaps\u00fcl\u00fc biyopsileri al\u0131nd\u0131. Olgular\u0131n cerrahi s\u0131ras\u0131nda ortalama ya\u015f\u0131 10.3 (da\u011f\u0131l\u0131m: 6-18) ay idi. Tam kat 1x1 cm anterior kaps\u00fcl ve LCF \u00f6rnekleri biyopsi olarak al\u0131nd\u0131. Kal\u00e7a eklem kaps\u00fcl\u00fc ve LCF\u2019de bulunan hedef \u00f6strojen h\u00fccrelerinin oran\u0131n\u0131 saptamak i\u00e7in monoklonal \u00f6strojen resept\u00f6r antikorlar\u0131 kullan\u0131larak imm\u00fcnohistokimyasal bir \u00e7al\u0131\u015fma yap\u0131ld\u0131. \\r\\nBulgular: Kontrol grubundaki LCF \u00f6rneklerinde saptanan \u00f6strojen resept\u00f6r\u00fc (\u00d6R) boyanma oran\u0131 1.6\u00b10.2%, kal\u00e7a eklem kaps\u00fcl\u00fcnde ise 1.3\u00b10.2% idi. GKD bulunan grupta ise LCF \u00f6rneklerinde saptanan \u00d6R boyanma oran\u0131 2.5\u00b10.3% , kal\u00e7a eklem kaps\u00fcl\u00fcnde ise 2.0\u00b10.3% idi. LCF ve kal\u00e7a eklem kaps\u00fcl\u00fcnde \u00d6R boyanma oran\u0131n\u0131n kontrol grubunda GKD bulunan gruba g\u00f6re istatistiksel olarak anlaml\u0131 \u015fekilde az oldu\u011fu g\u00f6zlendi (p&lt;0.001). Her iki grupta da, kal\u00e7a eklem kaps\u00fcl\u00fcndeki \u00d6R boyanma oran\u0131 LCF\u2019dekine g\u00f6re anlaml\u0131 derecede d\u00fc\u015f\u00fckt\u00fc (p&lt;0.01).\\r\\n\u00c7\u0131kar\u0131mlar: Ligamentum kapitis femoris ve kal\u00e7a eklem kaps\u00fcl\u00fcnde y\u00fcksek oranda bulunan \u00f6strojen resept\u00f6rleri, GKD\u2019nin etiyolojisinde \u00f6strojenin etkisini destekler niteliktedir.<\/jats:p>","DOI":"10.3944\/aott.2013.2772","type":"journal-article","created":{"date-parts":[[2013,6,12]],"date-time":"2013-06-12T05:31:47Z","timestamp":1371015107000},"page":"158-161","source":"Crossref","is-referenced-by-count":23,"title":["Estrogen receptors in hip joint capsule and ligamentum capitis femoris of babies with"],"prefix":"10.5152","volume":"47","author":[{"given":"Engin","family":"Eren Desteli","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ahmet","family":"Piskin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ali","family":"Birol G\u00fclman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Figen","family":"Kaymaz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bulent","family":"Koksal","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Murat","family":"Erdogan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"3111","published-online":{"date-parts":[[2020,2,7]]},"container-title":["Acta Orthopaedica et Traumatologica Turcica"],"original-title":[],"link":[{"URL":"https:\/\/aott.org.tr\/index.php\/pub\/article\/download\/2711\/2666","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,18]],"date-time":"2025-11-18T11:25:25Z","timestamp":1763465125000},"score":1,"resource":{"primary":{"URL":"https:\/\/aott.org.tr\/index.php\/pub\/article\/view\/2711"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,2,7]]},"references-count":0,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2013,1,3]]}},"URL":"https:\/\/doi.org\/10.3944\/aott.2013.2772","relation":{},"ISSN":["2589-1294","1017-995X"],"issn-type":[{"value":"2589-1294","type":"electronic"},{"value":"1017-995X","type":"print"}],"subject":[],"published":{"date-parts":[[2020,2,7]]}}}