{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,4]],"date-time":"2026-04-04T19:11:01Z","timestamp":1775329861004,"version":"3.50.1"},"reference-count":0,"publisher":"AVES YAYINCILIK A.\u015e.","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["AOTT"],"abstract":"<jats:p>Abstract\n\nObjective: Timing of surgery in hip fracture patients using antiplatelet agents is a controversial issue. Clopidogrel is an antiplatelet drug widely used in the treatment of many diseases. In this study, we aimed to investigate the outcomes of early surgery in hip fracture patients using clopidogrel.\nMethods: Elderly patients with femoral neck fractures who underwent open surgery between 2009 and 2014 were evaluated. Two hundred and eleven patients were included in the study. Patients were separated into 3 groups. Group 1 was constituted of patients using clopidogrel who had been operated on within 48 h after admission (n=74), Group 2 was constituted of patients using clopidogrel who had been operated on after the fifth day of admission (n=55), and Group 3 was constituted of patients not using clopidogrel who had been operated on within 48 h after admission (n=83). Length of hospital stay, amount of blood transfusion, rate of complication, and mortality rate were assessed for comparison of groups.\nResults: Age, sex, preoperative hemoglobin values, and ASA scores were not different between the groups. Amount of blood transfusions was higher in Group 1 (p=0.023). Duration of hospital stay was longer in Group 2 (p&lt;0.01), as was complication rate (25.4%) (p&lt;0.01). Mortality within 30 days and within the first 3 months post-surgery was significantly higher in Group 2 (p=0.031, p&lt;0.01; respectively).\nConclusion: Surgery should not be postponed in hip fracture patients using clopidogrel.\n\n\u00d6zet\n\nAma\u00e7: Antiplatelet tedavi al\u0131rken kal\u00e7a k\u0131r\u0131\u011f\u0131 geli\u015fen hastalar\u0131n cerrahi mu\u00a8dahale zamanlamas\u0131 tart\u0131\u015fmal\u0131 bir durumdur. Klopidogrel bir\u00e7ok hastal\u0131\u011f\u0131n tedavisinde yayg\u0131n olarak kullan\u0131lan antiplatelet bir ila\u00e7t\u0131r. Bu \u00e7al\u0131\u015fmada klopidogrel tedavisi al\u0131rken kal\u00e7a k\u0131r\u0131\u011f\u0131 olan hastalar\u0131n cerrahi mu\u00a8dahale sonu\u00e7lar\u0131n\u0131 kar\u015f\u0131la\u015ft\u0131rmay\u0131 ama\u00e7lad\u0131k.\n\n\u00c7al\u0131\u015fma plan\u0131: 2009 ile 2014 y\u0131llar\u0131 aras\u0131nda ileri ya\u015f femur boyun k\u0131r\u0131\u011f\u0131 nedeni ile a\u00e7\u0131k cerrahi uygulanan hastalar geriye d\u00f6nu\u00a8k olarak tarand\u0131. \u00c7al\u0131\u015fmaya 211 hasta dahil edildi. Hastalar; klopidogrel kullanan ve ilk 48 saat i\u00e7inde opere edilenler (grup 1, 74 hasta), klopidogrel kullanan ve be\u015finci gu\u00a8nden sonra opere edilen (grup 2, 55 hasta) ve herhangi bir antiagregan kullanmayan (grup 3, 82 hasta) olarak u\u00a8\u00e7 gruba ayr\u0131ld\u0131. Gruplar kan transfu\u00a8zyon miktar\u0131, yat\u0131\u015f su\u00a8resi, komplikasyon ve mortalite a\u00e7\u0131s\u0131ndan kar\u015f\u0131la\u015ft\u0131r\u0131ld\u0131.\n\nBulgular: Gruplar aras\u0131nda ya\u015f cinsiyet operasyon \u00f6ncesi hemoglobin de\u011ferleri ve ASA skorlar\u0131 a\u00e7\u0131s\u0131ndan anlaml\u0131 fark tespit edilemedi. Birinci gruptaki hastalar\u0131n daha fazla kan transfu\u00a8zyonu ihtiyac\u0131 oldu (p=0.023). \u0130kinci grupta hastanede kal\u0131\u015f su\u00a8resi daha yu\u00a8ksek idi (p&lt;0.01) ve daha yu\u00a8ksek oranda (%25.4) komplikasyon g\u00f6ru\u00a8ldu\u00a8 (p&lt;0.01). \u0130kinci gruptaki hastalarda ilk otuz gu\u00a8n i\u00e7inde ve ilk u\u00a8\u00e7 ay i\u00e7inde \u00f6lu\u00a8m oran\u0131 di\u011fer gruplara g\u00f6re daha yu\u00a8ksek bulundu (s\u0131ras\u0131yla, p=0.031, p&lt;0.01).\n\n\u00c7\u0131kar\u0131mlar: Kal\u00e7a k\u0131r\u0131klar\u0131nda cerrahi mu\u00a8dahale klopidogrel kullanan hastalarda ertelenmemelidir.\n\n \n\n \n\nDOI: 10.3944\/AOTT.2015.14.0160\n\nBu \u00f6zet, makalenin hen\u00fcz redaksiyonu tamamlanmam\u0131\u015f haline aittir ve bilgi verme ama\u00e7l\u0131d\u0131r. Yay\u0131n a\u015famas\u0131nda de\u011fi\u015fiklik g\u00f6sterebilir.<\/jats:p>","DOI":"10.3944\/aott.2015.14.0160","type":"journal-article","created":{"date-parts":[[2015,3,9]],"date-time":"2015-03-09T12:07:55Z","timestamp":1425902875000},"page":"249-254","source":"Crossref","is-referenced-by-count":5,"title":["Early surgery is feasible in patients with hip fractures who are on clopidogrel therapy"],"prefix":"10.5152","volume":"49","author":[{"given":"Sinan","family":"Zehir","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Regayip","family":"Zehir","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Taner","family":"Sarak","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"3111","published-online":{"date-parts":[[2020,2,7]]},"container-title":["Acta Orthopaedica et Traumatologica Turcica"],"original-title":[],"link":[{"URL":"https:\/\/aott.org.tr\/index.php\/pub\/article\/download\/2976\/2929","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,18]],"date-time":"2025-11-18T11:09:35Z","timestamp":1763464175000},"score":1,"resource":{"primary":{"URL":"https:\/\/aott.org.tr\/index.php\/pub\/article\/view\/2976"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,2,7]]},"references-count":0,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2015,1,3]]}},"URL":"https:\/\/doi.org\/10.3944\/aott.2015.14.0160","relation":{"has-review":[{"id-type":"doi","id":"10.3410\/f.725669720.793508783","asserted-by":"object"}]},"ISSN":["2589-1294","1017-995X"],"issn-type":[{"value":"2589-1294","type":"electronic"},{"value":"1017-995X","type":"print"}],"subject":[],"published":{"date-parts":[[2020,2,7]]}}}