{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T21:48:23Z","timestamp":1792100903716,"version":"4.4.0"},"reference-count":59,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2008,11,1]],"date-time":"2008-11-01T00:00:00Z","timestamp":1225497600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,3,1]],"date-time":"2023-03-01T00:00:00Z","timestamp":1677628800000},"content-version":"vor","delay-in-days":5233,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The American Journal of Clinical Nutrition"],"published-print":{"date-parts":[[2008,11]]},"DOI":"10.3945\/ajcn.2008.26149","type":"journal-article","created":{"date-parts":[[2021,2,12]],"date-time":"2021-02-12T21:45:44Z","timestamp":1613166344000},"page":"1378-1387","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":99,"title":["Dual fortification of salt with iodine and iron: a randomized, double-blind, controlled trial of micronized ferric pyrophosphate and encapsulated ferrous fumarate in southern India"],"prefix":"10.1016","volume":"88","author":[{"given":"Maria","family":"Andersson","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Prashanth","family":"Thankachan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sumithra","family":"Muthayya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ramakrishna B","family":"Goud","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anura V","family":"Kurpad","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard F","family":"Hurrell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael B","family":"Zimmermann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.3945\/ajcn.2008.26149_bib1","series-title":"Iron deficiency anaemia. Assessment, prevention and control.","year":"2001"},{"key":"10.3945\/ajcn.2008.26149_bib2","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/S0140-6736(07)60076-2","article-title":"Child development: risk factors for adverse outcomes in developing countries.","volume":"369","author":"Walker","year":"2007","journal-title":"Lancet"},{"key":"10.3945\/ajcn.2008.26149_bib3","unstructured":"de Benoist B, McLean E, Andersson M, Rogers L. Iodine deficiency in 2007: global progress since 2003. Food Nutr Bull (in press)."},{"key":"10.3945\/ajcn.2008.26149_bib4","doi-asserted-by":"crossref","first-page":"813","DOI":"10.1093\/ajcn\/52.5.813","article-title":"Impaired thermoregulation and thyroid function in iron-deficiency anemia.","volume":"52","author":"Beard","year":"1990","journal-title":"Am J Clin Nutr"},{"key":"10.3945\/ajcn.2008.26149_bib5","doi-asserted-by":"crossref","first-page":"1401","DOI":"10.1093\/jn\/128.8.1401","article-title":"Plasma thyroid hormone kinetics are altered in iron-deficient rats.","volume":"128","author":"Beard","year":"1998","journal-title":"J Nutr"},{"key":"10.3945\/ajcn.2008.26149_bib6","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1146\/annurev.nutr.26.061505.111236","article-title":"The influence of iron status on iodine utilization and thyroid function.","volume":"26","author":"Zimmermann","year":"2006","journal-title":"Annu Rev Nutr"},{"key":"10.3945\/ajcn.2008.26149_bib7","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1093\/ajcn\/71.1.88","article-title":"Persistence of goiter despite oral iodine supplementation in goitrous children with iron deficiency anemia in Cote d'Ivoire.","volume":"71","author":"Zimmermann","year":"2000","journal-title":"Am J Clin Nutr"},{"key":"10.3945\/ajcn.2008.26149_bib8","doi-asserted-by":"crossref","first-page":"743","DOI":"10.1093\/ajcn\/75.4.743","article-title":"Treatment of iron deficiency in goitrous children improves the efficacy of iodized salt in Cote d'Ivoire.","volume":"75","author":"Hess","year":"2002","journal-title":"Am J Clin Nutr"},{"key":"10.3945\/ajcn.2008.26149_bib9","series-title":"A guide for programme managers.","article-title":"Assessment of iodine deficiency disorders and monitoring their elimination.","year":"2007"},{"key":"10.3945\/ajcn.2008.26149_bib10","doi-asserted-by":"crossref","first-page":"648","DOI":"10.1093\/ajcn\/38.4.648","article-title":"Iron fortification: an update.","volume":"38","author":"Cook","year":"1983","journal-title":"Am J Clin Nutr"},{"key":"10.3945\/ajcn.2008.26149_bib11","doi-asserted-by":"crossref","first-page":"1395","DOI":"10.1093\/ajcn\/28.12.1395","article-title":"Fortification of common salt with iron: effect of chemical additives on stability and bioavailability.","volume":"28","author":"Rao","year":"1975","journal-title":"Am J Clin Nutr"},{"key":"10.3945\/ajcn.2008.26149_bib12","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1177\/156482659401500119","article-title":"Fortification of salt with iron and iodine to control anaemia and goitre: development of a new formula with good stability and bioavailability of iron and iodine.","volume":"15","author":"Narasinga Rao","year":"1994","journal-title":"Food Nutr Bull"},{"key":"10.3945\/ajcn.2008.26149_bib13","first-page":"203","article-title":"Impact evaluation of iron & iodine fortified salt.","volume":"108","author":"Nair","year":"1998","journal-title":"Indian J Med Res"},{"key":"10.3945\/ajcn.2008.26149_bib14","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1093\/ajcn\/77.2.425","article-title":"Dual fortification of salt with iodine and microencapsulated iron: a randomized, double-blind, controlled trial in Moroccan schoolchildren.","volume":"77","author":"Zimmermann","year":"2003","journal-title":"Am J Clin Nutr"},{"key":"10.3945\/ajcn.2008.26149_bib15","first-page":"531","article-title":"Estimation of iodine in salt fortified with iodine & iron.","volume":"123","author":"Ranganathan","year":"2006","journal-title":"Indian J Med Res"},{"key":"10.3945\/ajcn.2008.26149_bib16","doi-asserted-by":"crossref","first-page":"806S","DOI":"10.1093\/jn\/132.4.806S","article-title":"Fortification: overcoming technical and practical barriers.","volume":"132","author":"Hurrell","year":"2002","journal-title":"J Nutr"},{"key":"10.3945\/ajcn.2008.26149_bib17","doi-asserted-by":"crossref","first-page":"2129","DOI":"10.1111\/j.1365-2621.2003.tb07031.x","article-title":"Dual fortification of salt with iodine and encapsulated iron compounds: stability and acceptability testing in Morocco and C\u00f4te d'Ivoire.","volume":"68","author":"Wegm\u00fcller","year":"2003","journal-title":"J Food Sci"},{"key":"10.3945\/ajcn.2008.26149_bib18","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1079\/BJN20041018","article-title":"A micronised, dispersible ferric pyrophosphate with high relative bioavailability in man.","volume":"91","author":"Fidler","year":"2004","journal-title":"Br J Nutr"},{"key":"10.3945\/ajcn.2008.26149_bib19","doi-asserted-by":"crossref","first-page":"952","DOI":"10.1093\/ajcn\/80.4.952","article-title":"Dual fortification of salt with iodine and micronized ferric pyrophosphate: a randomized, double-blind, controlled trial.","volume":"80","author":"Zimmermann","year":"2004","journal-title":"Am J Clin Nutr"},{"key":"10.3945\/ajcn.2008.26149_bib20","doi-asserted-by":"crossref","first-page":"1283","DOI":"10.1093\/ajcn\/80.5.1283","article-title":"Triple fortification of salt with microcapsules of iodine, iron, and vitamin A.","volume":"80","author":"Zimmermann","year":"2004","journal-title":"Am J Clin Nutr"},{"key":"10.3945\/ajcn.2008.26149_bib21","doi-asserted-by":"crossref","first-page":"1814","DOI":"10.1093\/jn\/136.7.1814","article-title":"Salt dual-fortified with iodine and micronized ground ferric pyrophosphate affects iron status but not hemoglobin in children in Cote d'Ivoire.","volume":"136","author":"Wegmuller","year":"2006","journal-title":"J Nutr"},{"key":"10.3945\/ajcn.2008.26149_bib22","doi-asserted-by":"crossref","first-page":"1274","DOI":"10.1093\/ajcn\/49.6.1274","article-title":"Iron fortification of infant cereals: a proposal for the use of ferrous fumarate or ferrous succinate.","volume":"49","author":"Hurrell","year":"1989","journal-title":"Am J Clin Nutr"},{"key":"10.3945\/ajcn.2008.26149_bib23","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1111\/j.1740-8709.2006.00060.x","article-title":"Multi-micronutrient Sprinkles including a low dose of iron provided as microencapsulated ferrous fumarate improves haematologic indices in anaemic children: a randomized clinical trial.","volume":"2","author":"Christofides","year":"2006","journal-title":"Matern Child Nutr"},{"key":"10.3945\/ajcn.2008.26149_bib24","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1093\/jn\/129.1.117","article-title":"Iron is well absorbed by healthy adults after ingestion of double-fortified (iron and dextran-coated iodine) table salt and urinary iodine excretion is unaffected.","volume":"129","author":"Sattarzadeh","year":"1999","journal-title":"J Nutr"},{"key":"10.3945\/ajcn.2008.26149_bib25","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1177\/156482650202300209","article-title":"Iodine stability in salt double-fortified with iron and iodine.","volume":"23","author":"Diosady","year":"2002","journal-title":"Food Nutr Bull"},{"key":"10.3945\/ajcn.2008.26149_bib26","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1016\/S0963-9969(01)00166-1","article-title":"Microencapsulation for iodine stability in salt fortified with ferrous fumarate and potassium iodide.","volume":"35","author":"Diosady","year":"2002","journal-title":"Food Res Int"},{"key":"10.3945\/ajcn.2008.26149_bib27","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1177\/156482650402500306","article-title":"Stability of salt double-fortified with ferrous fumarate and potassium iodate or iodide under storage and distribution conditions in Kenya.","volume":"25","author":"Oshinowo","year":"2004","journal-title":"Food Nutr Bull"},{"key":"10.3945\/ajcn.2008.26149_bib28","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1024\/0300-9831.74.6.453","article-title":"The potential of encapsulated iron compounds in food fortification: a review.","volume":"74","author":"Zimmermann","year":"2004","journal-title":"Int J Vitam Nutr Res"},{"key":"10.3945\/ajcn.2008.26149_bib29","first-page":"46","article-title":"Anaemia and micronutrient deficiency.","volume":"16","author":"Rao","year":"2003","journal-title":"Natl Med J India"},{"key":"10.3945\/ajcn.2008.26149_bib30","doi-asserted-by":"crossref","first-page":"865","DOI":"10.1038\/sj.ejcn.1602613","article-title":"Low anemia prevalence in school-aged children in Bangalore, South India: possible effect of school health initiatives","volume":"61","author":"Muthayya","year":"2007","journal-title":"Eur J Clin Nutr"},{"key":"10.3945\/ajcn.2008.26149_bib31","series-title":"National Family Health Survey (NFHS-3), 2005-2006: India.","year":"2007"},{"key":"10.3945\/ajcn.2008.26149_bib32","first-page":"399","article-title":"Changing trends in malaria\u2014a decade's experience at a referral hospital.","volume":"46","author":"Sitalakshmi","year":"2003","journal-title":"Indian J Pathol Microbiol"},{"key":"10.3945\/ajcn.2008.26149_bib33","doi-asserted-by":"crossref","first-page":"822","DOI":"10.1093\/ajcn\/84.4.822","article-title":"Extruded rice fortified with micronized ground ferric pyrophosphate reduces iron deficiency in Indian schoolchildren: a double-blind randomized controlled trial.","volume":"84","author":"Moretti","year":"2006","journal-title":"Am J Clin Nutr"},{"key":"10.3945\/ajcn.2008.26149_bib34","article-title":"Nutritive value of Indian foods.","author":"Gopalan","year":"1989"},{"key":"10.3945\/ajcn.2008.26149_bib35","unstructured":"US Department of Agriculture. USDA national nutrient database for standard reference, release 19, 2006.Internet: http:\/\/www.ars.usda.gov\/nutrientdata (accessed 20 August 2006)."},{"key":"10.3945\/ajcn.2008.26149_bib36","series-title":"Double fortified salt premix: product description.","year":"2005"},{"key":"10.3945\/ajcn.2008.26149_bib37","first-page":"648","article-title":"Iron absorption from habitual diets of Indians studied by the extrinsic tag technique.","volume":"77","author":"Rao","year":"1983","journal-title":"Indian J Med Res"},{"key":"10.3945\/ajcn.2008.26149_bib38","series-title":"Report of a Joint FAO\/WHO Expert Consultation.","article-title":"Requirements of vitamin A, iron, folate and vitamin B12.","year":"1988"},{"key":"10.3945\/ajcn.2008.26149_bib39","doi-asserted-by":"crossref","first-page":"3301","DOI":"10.1093\/jn\/134.12.3301","article-title":"Particle size reduction and encapsulation affect the bioavailability of ferric pyrophosphate in rats.","volume":"134","author":"Wegmuller","year":"2004","journal-title":"J Nutr"},{"key":"10.3945\/ajcn.2008.26149_bib40","article-title":"Guidelines on food fortification with micronutrients.","author":"Allen","year":"2006"},{"key":"10.3945\/ajcn.2008.26149_bib41","article-title":"Sensory evaluation techniques.","author":"Meilgaard","year":"1991"},{"key":"10.3945\/ajcn.2008.26149_bib42","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1093\/clinchem\/42.2.239","article-title":"Ammonium persulfate: a safe alternative oxidizing reagent for measuring urinary iodine.","volume":"42","author":"Pino","year":"1996","journal-title":"Clin Chem"},{"key":"10.3945\/ajcn.2008.26149_bib43","doi-asserted-by":"crossref","first-page":"2060","DOI":"10.1093\/clinchem\/45.12.2060","article-title":"Zinc protoporphyrin: a metabolite with a mission.","volume":"45","author":"Labbe","year":"1999","journal-title":"Clin Chem"},{"key":"10.3945\/ajcn.2008.26149_bib44","series-title":"Report of a joint technical consultation on the assessment of iron status at the population level.","article-title":"Assessing the iron status of populations.","year":"2004"},{"key":"10.3945\/ajcn.2008.26149_bib45","doi-asserted-by":"crossref","first-page":"2184","DOI":"10.1093\/clinchem\/38.11.2184","article-title":"Washing erythrocytes to remove interferents in measurements of zinc protoporphyrin by front-face hematofluorometry.","volume":"38","author":"Hastka","year":"1992","journal-title":"Clin Chem"},{"key":"10.3945\/ajcn.2008.26149_bib46","doi-asserted-by":"crossref","first-page":"615","DOI":"10.1093\/ajcn\/81.3.615","article-title":"Serum transferrin receptor and zinc protoporphyrin as indicators of iron status in African children.","volume":"81","author":"Zimmermann","year":"2005","journal-title":"Am J Clin Nutr"},{"key":"10.3945\/ajcn.2008.26149_bib47","doi-asserted-by":"crossref","first-page":"3359","DOI":"10.1182\/blood-2002-10-3071","article-title":"The quantitative assessment of body iron.","volume":"101","author":"Cook","year":"2003","journal-title":"Blood"},{"key":"10.3945\/ajcn.2008.26149_bib48","article-title":"Managing elevated blood lead levels among young children: recommendations from the Advisory Committee on Childhood Lead Poisoning Prevention.","author":"Harvey","year":"2002"},{"key":"10.3945\/ajcn.2008.26149_bib49","doi-asserted-by":"crossref","first-page":"660","DOI":"10.2471\/BLT.07.043497","article-title":"Development of a WHO growth reference for school-aged children and adolescents.","volume":"85","author":"de Onis","year":"2007","journal-title":"Bull World Health Organ"},{"key":"10.3945\/ajcn.2008.26149_bib50","doi-asserted-by":"crossref","first-page":"S7","DOI":"10.1301\/002966402320285137","article-title":"How to ensure adequate iron absorption from iron-fortified food.","volume":"60","author":"Hurrell","year":"2002","journal-title":"Nutr Rev"},{"key":"10.3945\/ajcn.2008.26149_bib51","doi-asserted-by":"crossref","first-page":"632","DOI":"10.1093\/ajcn.83.3.632","article-title":"Iron status and food matrix strongly affect the relative bioavailability of ferric pyrophosphate in humans.","volume":"83","author":"Moretti","year":"2006","journal-title":"Am J Clin Nutr"},{"key":"10.3945\/ajcn.2008.26149_bib52","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1177\/15648265020233S126","article-title":"Bioavailability of iron from micro-encapsulated iron sprinkle supplement.","volume":"23","author":"Liyanage","year":"2002","journal-title":"Food Nutr Bull"},{"key":"10.3945\/ajcn.2008.26149_bib53","doi-asserted-by":"crossref","first-page":"S585","DOI":"10.1177\/15648265070284S411","article-title":"Iron fortification: its efficacy and safety in relation to infections.","volume":"28","author":"Hurrell","year":"2007","journal-title":"Food Nutr Bull"},{"key":"10.3945\/ajcn.2008.26149_bib54","first-page":"388","article-title":"Stability of iodine in iodized salt used for the correction IDD.","volume":"18","author":"Diosady","year":"1997","journal-title":"Food Nutr Bull"},{"key":"10.3945\/ajcn.2008.26149_bib55","doi-asserted-by":"crossref","DOI":"10.2202\/1556-3758.1110","article-title":"An investigation of the stability of double fortified salt during storage and distribution in Nigeria.","volume":"3","author":"Oshinowo","year":"2007","journal-title":"Int J Food Eng"},{"key":"10.3945\/ajcn.2008.26149_bib56","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1016\/0308-8146(92)90158-X","article-title":"Fortification of common salt with iron\u2014use of polyphosphate stabilizers.","volume":"45","author":"Ranganathan","year":"1992","journal-title":"Food Chem"},{"key":"10.3945\/ajcn.2008.26149_bib57","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1177\/156482650702800111","article-title":"A multicenter community study on the efficacy of double-fortified salt.","volume":"28","author":"Vinodkumar","year":"2007","journal-title":"Food Nutr Bull"},{"key":"10.3945\/ajcn.2008.26149_bib58","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1177\/156482650702800112","article-title":"Stability of iodine in salt fortified with iodine and iron.","volume":"28","author":"Ranganathan","year":"2007","journal-title":"Food Nutr Bull"},{"key":"10.3945\/ajcn.2008.26149_bib59","series-title":"Reducing salt intake in populations: report of a WHO forum and technical meeting, 5-7 October 2006, Paris, France.","year":"2007"}],"container-title":["The American Journal of Clinical Nutrition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002916523233705?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002916523233705?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2023,5,30]],"date-time":"2023-05-30T07:35:34Z","timestamp":1685432134000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0002916523233705"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,11]]},"references-count":59,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2008,11]]}},"alternative-id":["S0002916523233705"],"URL":"https:\/\/doi.org\/10.3945\/ajcn.2008.26149","relation":{},"ISSN":["0002-9165"],"issn-type":[{"value":"0002-9165","type":"print"}],"subject":[],"published":{"date-parts":[[2008,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Dual fortification of salt with iodine and iron: a randomized, double-blind, controlled trial of micronized ferric pyrophosphate and encapsulated ferrous fumarate in southern India","name":"articletitle","label":"Article Title"},{"value":"The American Journal of Clinical Nutrition","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.3945\/ajcn.2008.26149","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2008 American Society for Nutrition. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}