{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,9]],"date-time":"2026-01-09T22:40:40Z","timestamp":1767998440579,"version":"3.49.0"},"reference-count":39,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2009,1,1]],"date-time":"2009-01-01T00:00:00Z","timestamp":1230768000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2009,1,1]],"date-time":"2009-01-01T00:00:00Z","timestamp":1230768000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,2,23]],"date-time":"2023-02-23T00:00:00Z","timestamp":1677110400000},"content-version":"vor","delay-in-days":5166,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The American Journal of Clinical Nutrition"],"published-print":{"date-parts":[[2009,1]]},"DOI":"10.3945\/ajcn.2008.26287","type":"journal-article","created":{"date-parts":[[2008,12,5]],"date-time":"2008-12-05T06:59:10Z","timestamp":1228460350000},"page":"363-371","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":21,"title":["Hemoglobin and hematocrit values are higher and prevalence of anemia is lower in the post\u2013folic acid fortification period than in the pre\u2013folic acid fortification period in US adults"],"prefix":"10.1016","volume":"89","author":[{"given":"Vijay","family":"Ganji","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohammad R","family":"Kafai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.3945\/ajcn.2008.26287_bib1","first-page":"8781","article-title":"Food and Drug Administration. Food standards: amendment of standards of identify for enriched products to require addition of folic acid.","volume":"61","year":"1996","journal-title":"Fed Regist"},{"key":"10.3945\/ajcn.2008.26287_bib2","series-title":"Recommendations for the use of folic acid to reduce the number of cases of spina bifida and other neural tube defects.","year":"1992"},{"key":"10.3945\/ajcn.2008.26287_bib3","doi-asserted-by":"crossref","first-page":"2792","DOI":"10.1093\/jn\/132.9.2792","article-title":"Folic acid intake from fortification in United States exceeds predictions.","volume":"132","author":"Choumenkovitch","year":"2002","journal-title":"J Nutr"},{"key":"10.3945\/ajcn.2008.26287_bib4","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1093\/ajcn\/77.1.221","article-title":"Effect of food fortification on folic acid intake in the United States.","volume":"77","author":"Quinlivan","year":"2003","journal-title":"Am J Clin Nutr"},{"key":"10.3945\/ajcn.2008.26287_bib5","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1016\/S0308-8146(00)00116-3","article-title":"Total folate in enriched cereal-grain products in the United States following folate fortification.","volume":"70","author":"Rader","year":"2000","journal-title":"Food Chem"},{"key":"10.3945\/ajcn.2008.26287_bib6","doi-asserted-by":"crossref","first-page":"2981","DOI":"10.1001\/jama.285.23.2981","article-title":"Impact of folic acid fortification of the US food supply on the occurrence of neural tube defects.","volume":"285","author":"Honein","year":"2001","journal-title":"JAMA"},{"key":"10.3945\/ajcn.2008.26287_bib7","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1093\/jn\/136.1.153","article-title":"Trends in serum folate, red blood cell folate, and circulating total homocysteine concentrations in the US: analysis of data from the National Health and Nutrition Examination Surveys, 1988\u20132002.","volume":"136","author":"Ganji","year":"2006","journal-title":"J Nutr"},{"key":"10.3945\/ajcn.2008.26287_bib8","doi-asserted-by":"crossref","first-page":"1449","DOI":"10.1056\/NEJM199905133401901","article-title":"The effect of folic acid fortification on plasma folate and total homocysteine concentrations.","volume":"340","author":"Jacques","year":"1999","journal-title":"N Engl J Med"},{"key":"10.3945\/ajcn.2008.26287_bib9","doi-asserted-by":"crossref","first-page":"3277","DOI":"10.1093\/jn\/131.12.3277","article-title":"Folic acid fortification increases red blood cell folate concentrations in the Framingham study.","volume":"131","author":"Choumenkovitch","year":"2001","journal-title":"J Nutr"},{"key":"10.3945\/ajcn.2008.26287_bib10","doi-asserted-by":"crossref","first-page":"915","DOI":"10.1016\/S0140-6736(99)03227-4","article-title":"Trends in serum folate after food fortification.","volume":"354","author":"Lawrence","year":"1999","journal-title":"Lancet"},{"key":"10.3945\/ajcn.2008.26287_bib11","doi-asserted-by":"crossref","first-page":"718","DOI":"10.1093\/ajcn\/86.3.718","article-title":"Trends in blood folate and vitamin B-12 concentrations in the United States, 1988\u20132004.","volume":"86","author":"Pfeiffer","year":"2007","journal-title":"Am J Clin Nutr"},{"key":"10.3945\/ajcn.2008.26287_bib12","doi-asserted-by":"crossref","first-page":"989","DOI":"10.1093\/ajcn\/84.5.989","article-title":"Population reference values for plasma total homocysteine concentrations in US adults after the fortification of cereals with folic acid.","volume":"84","author":"Ganji","year":"2006","journal-title":"Am J Clin Nutr"},{"key":"10.3945\/ajcn.2008.26287_bib13","doi-asserted-by":"crossref","first-page":"2253","DOI":"10.1093\/jn\/135.9.2253","article-title":"Population references for plasma total homocysteine concentrations for US children and adolescents in the post-folic acid fortification era.","volume":"135","author":"Ganji","year":"2005","journal-title":"J Nutr"},{"key":"10.3945\/ajcn.2008.26287_bib14","series-title":"Third National Health and Nutrition Examination Survey, 1988\u20131994, NHANES III examination data file. Public use data file documentation no. 76200.","year":"1996"},{"key":"10.3945\/ajcn.2008.26287_bib15","series-title":"Third National Health and Nutrition Examination Survey, 1988\u20131994. NHANES III household adult data file. Public use data file documentation no. 77560.","year":"1996"},{"key":"10.3945\/ajcn.2008.26287_bib16","series-title":"Third National Health and Nutrition Examination Survey, 1988\u20131994. NHANES III laboratory data file. Public use data file documentation no. 76300.","year":"1996"},{"key":"10.3945\/ajcn.2008.26287_bib17","series-title":"National Health and Nutrition Examination Survey, 1999\u20132000. Public use data files. Centers for Disease Control and Prevention homepage.","year":"2007"},{"key":"10.3945\/ajcn.2008.26287_bib18","series-title":"National Health and Nutrition Examination Survey, 2001\u20132002. Public use data files. Centers for Disease Control and Prevention homepage.","year":"2007"},{"key":"10.3945\/ajcn.2008.26287_bib19","series-title":"National Health and Nutrition Examination Survey, 2003\u20132004. Public use data files. Centers for Disease Control and Prevention homepage.","year":"2007"},{"key":"10.3945\/ajcn.2008.26287_bib20","series-title":"Third National Health and Nutrition Examination Survey, 1988\u20131994. NHANES III reference manuals and reports.","year":"1988"},{"key":"10.3945\/ajcn.2008.26287_bib21","series-title":"National Health and Nutrition Examination Survey. Version current 1999. Survey operations manuals, brochures, consent documents, March 2001. Public use data files. Centers for Disease Control and Prevention homepage.","year":"1999"},{"key":"10.3945\/ajcn.2008.26287_bib22","series-title":"Ratio of income to poverty level.","year":"2003"},{"key":"10.3945\/ajcn.2008.26287_bib23","series-title":"Nutrient data base for standard reference.","year":"2003"},{"key":"10.3945\/ajcn.2008.26287_bib24","series-title":"Laboratory procedures used for the third National Health and Nutrition Examination Survey, 1988\u20131994","author":"Gunter","year":"1996"},{"key":"10.3945\/ajcn.2008.26287_bib25","series-title":"National Health and Nutrition Examination Survey, 2001\u20132002. Laboratory procedures manual. Centers for Disease Control and Prevention homepage.","year":"2001"},{"key":"10.3945\/ajcn.2008.26287_bib26","series-title":"Iron deficiency anemia, assessment, prevention, and control. a guide for program managers.","year":"2007"},{"key":"10.3945\/ajcn.2008.26287_bib27","doi-asserted-by":"crossref","first-page":"1409","DOI":"10.1093\/ajcn\/85.5.1409","article-title":"Race-ethnicity differences in folic acid intake in women of childbearing age in the United States after folic acid fortification: findings from the National Health and Nutrition Examination Survey, 2001\u20132002.","volume":"85","author":"Yang","year":"2007","journal-title":"Am J Clin Nutr"},{"key":"10.3945\/ajcn.2008.26287_bib28","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1093\/ajcp\/99.1.57","article-title":"Changing etiology of macrocytosis: zidovudine as a frequent causative factor.","volume":"99","author":"Snower","year":"1993","journal-title":"Am J Clin Pathol"},{"key":"10.3945\/ajcn.2008.26287_bib29","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1016\/S0002-9629(15)40772-4","article-title":"Etiology and diagnostic evaluation of macrocytosis.","volume":"319","author":"Savage","year":"2000","journal-title":"Am J Med Sci"},{"key":"10.3945\/ajcn.2008.26287_bib30","doi-asserted-by":"crossref","first-page":"236","DOI":"10.3121\/cmr.4.3.236","article-title":"Megaloblastic anemia and other causes of macrocytosis.","volume":"4","author":"Aslinia","year":"2006","journal-title":"Clin Med Res"},{"key":"10.3945\/ajcn.2008.26287_bib31","doi-asserted-by":"crossref","first-page":"277S","DOI":"10.1093\/ajcn\/85.1.277S","article-title":"Multivitamin-multimineral supplements: who uses them?","volume":"85","author":"Rock","year":"2007","journal-title":"Am J Clin Nutr"},{"key":"10.3945\/ajcn.2008.26287_bib32","doi-asserted-by":"crossref","first-page":"1106","DOI":"10.1016\/j.jada.2005.04.010","article-title":"Association of dietary supplement use with specific micronutrient intakes among middle-aged American men and women: the INTERMAP Study.","volume":"105","author":"Archer","year":"2005","journal-title":"J Am Diet Assoc"},{"key":"10.3945\/ajcn.2008.26287_bib33","doi-asserted-by":"crossref","first-page":"1187","DOI":"10.1093\/ajcn\/86.4.1187","article-title":"Proportion of individuals with low serum vitamin B-12 concentrations without macrocytosis is higher in the post-folic acid fortification period than in pre-folic acid fortification period.","volume":"86","author":"Wyckoff","year":"2007","journal-title":"Am J Clin Nutr"},{"key":"10.3945\/ajcn.2008.26287_bib34","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1093\/jn\/132.2.289","article-title":"The Chilean flour folic acid fortification program reduces serum homocysteine levels and masks vitamin B-deficiency in elderly people.","volume":"132","author":"Hirsch","year":"2002","journal-title":"J Nutr"},{"key":"10.3945\/ajcn.2008.26287_bib35","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1093\/ajcn\/85.1.193","article-title":"Folate and vitamin B-12 status in relation to anemia, macrocytosis, and cognitive impairment in older Americans in the age of folic acid fortification.","volume":"85","author":"Morris","year":"2007","journal-title":"Am J Clin Nutr"},{"key":"10.3945\/ajcn.2008.26287_bib36","doi-asserted-by":"crossref","first-page":"1474","DOI":"10.1093\/ajcn\/77.6.1474","article-title":"Low vitamin B-12 concentrations in patients without anemia: the effect of folic acid fortification of grain.","volume":"77","author":"Mills","year":"2003","journal-title":"Am J Clin Nutr"},{"key":"10.3945\/ajcn.2008.26287_bib37","doi-asserted-by":"crossref","first-page":"1995","DOI":"10.1073\/pnas.0709487104","article-title":"In vitamin B-12 deficiency, higher serum folate is associated with increased total homocysteine and methylmalonic acid concentrations.","volume":"104","author":"Selhub","year":"2007","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.3945\/ajcn.2008.26287_bib38","doi-asserted-by":"crossref","first-page":"1889","DOI":"10.1093\/ajcn\/65.6.1889","article-title":"Let\u2019s increase folic acid fortification and include vitamin B-12.","volume":"65","author":"Oakley","year":"1997","journal-title":"Am J Clin Nutr"},{"key":"10.3945\/ajcn.2008.26287_bib39","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1186\/1471-2458-7-41","article-title":"Folic acid fortification and public health: report on threshold doses above which unmetabolized folic acid appear in serum.","volume":"7","author":"Sweeney","year":"2007","journal-title":"BMC Public Health"}],"container-title":["The American Journal of Clinical Nutrition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002916523239441?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002916523239441?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/academic.oup.com\/ajcn\/article-pdf\/89\/1\/363\/25425164\/363.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,12,12]],"date-time":"2024-12-12T00:54:13Z","timestamp":1733964853000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0002916523239441"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,1]]},"references-count":39,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2009,1]]}},"alternative-id":["S0002916523239441"],"URL":"https:\/\/doi.org\/10.3945\/ajcn.2008.26287","relation":{},"ISSN":["0002-9165"],"issn-type":[{"value":"0002-9165","type":"print"}],"subject":[],"published":{"date-parts":[[2009,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Hemoglobin and hematocrit values are higher and prevalence of anemia is lower in the post\u2013folic acid fortification period than in the pre\u2013folic acid fortification period in US adults","name":"articletitle","label":"Article Title"},{"value":"The American Journal of Clinical Nutrition","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.3945\/ajcn.2008.26287","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2009 American Society for Nutrition. Published by Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}