{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,3]],"date-time":"2025-12-03T17:34:32Z","timestamp":1764783272028},"reference-count":46,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2011,5,1]],"date-time":"2011-05-01T00:00:00Z","timestamp":1304208000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,2,10]],"date-time":"2023-02-10T00:00:00Z","timestamp":1675987200000},"content-version":"vor","delay-in-days":4303,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Nutrition"],"published-print":{"date-parts":[[2011,5]]},"DOI":"10.3945\/jn.110.132134","type":"journal-article","created":{"date-parts":[[2011,3,17]],"date-time":"2011-03-17T00:54:33Z","timestamp":1300323273000},"page":"957-963","update-policy":"http:\/\/dx.doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":18,"title":["Vitamin A Modifies the Intestinal Chemokine and Cytokine Responses to Norovirus Infection in Mexican Children1,2"],"prefix":"10.1016","volume":"141","author":[{"given":"Kurt Z.","family":"Long","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Coralith","family":"Garcia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"GwangPyo","family":"Ko","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jose I.","family":"Santos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abdullah","family":"Al Mamun","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jorge L.","family":"Rosado","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Herbert L.","family":"DuPont","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nanda","family":"Nathakumar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.3945\/jn.110.132134_bib1","series-title":"Effectiveness of vitamin A supplementation in the control of young child mortality in developing countries.","author":"Beaton","year":"1993"},{"key":"10.3945\/jn.110.132134_bib2","doi-asserted-by":"crossref","first-page":"898","DOI":"10.1001\/jama.1993.03500070078033","article-title":"Vitamin A supplementation and child mortality. A meta-analysis.","volume":"269","author":"Fawzi","year":"1993","journal-title":"JAMA."},{"key":"10.3945\/jn.110.132134_bib3","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/0140-6736(93)91879-Q","article-title":"Vitamin A supplementation in northern Ghana: effects on clinic attendances, hospital admissions, and child mortality.","volume":"342","year":"1993","journal-title":"Lancet."},{"key":"10.3945\/jn.110.132134_bib4","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1016\/S0140-6736(94)92998-X","article-title":"Effect of vitamin A supplementation on diarrhoea and acute lower-respiratory-tract infections in young children in Brazil.","volume":"344","author":"Barreto","year":"1994","journal-title":"Lancet."},{"key":"10.3945\/jn.110.132134_bib5","doi-asserted-by":"crossref","first-page":"434","DOI":"10.1093\/jn\/126.2.434","article-title":"Vitamin A supplementation fails to reduce incidence of acute respiratory illness and diarrhea in preschool-age Indonesian children.","volume":"126","author":"Dibley","year":"1996","journal-title":"J Nutr."},{"key":"10.3945\/jn.110.132134_bib6","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1016\/S0140-6736(07)61693-6","article-title":"What works. Interventions for maternal and child undernutrition and survival.","volume":"371","author":"Bhutta","year":"2008","journal-title":"Lancet."},{"key":"10.3945\/jn.110.132134_bib7","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1067\/mpd.2003.116","article-title":"Vitamin A supplementation and childhood morbidity from diarrhea and respiratory infections: a meta-analysis.","volume":"142","author":"Grotto","year":"2003","journal-title":"J Pediatr."},{"key":"10.3945\/jn.110.132134_bib8","doi-asserted-by":"crossref","first-page":"1673","DOI":"10.1002\/eji.1830250629","article-title":"Vitamin A deficiency results in a priming environment conducive for Th1 cell development.","volume":"25","author":"Cantorna","year":"1995","journal-title":"Eur J Immunol."},{"key":"10.3945\/jn.110.132134_bib9","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1016\/j.toxlet.2004.01.010","article-title":"Effect of retinoids on LPS-induced COX-2 expression and COX-2 associated PGE(2) release from mouse peritoneal macrophages and TNF-alpha release from rat peripheral blood mononuclear cells.","volume":"150","author":"Kim","year":"2004","journal-title":"Toxicol Lett"},{"key":"10.3945\/jn.110.132134_bib10","doi-asserted-by":"crossref","first-page":"S257","DOI":"10.1093\/jn\/134.1.257S","article-title":"Carotenoid action on the immune response.","volume":"134","author":"Chew","year":"2004","journal-title":"J Nutr."},{"key":"10.3945\/jn.110.132134_bib11","doi-asserted-by":"crossref","first-page":"S225","DOI":"10.1093\/jn\/134.1.225S","article-title":"From 1989 to 2001: what have we learned about the \"biological actions of beta-carotene\".","volume":"134","author":"Bendich","year":"2004","journal-title":"J Nutr."},{"key":"10.3945\/jn.110.132134_bib12","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1086\/341085","article-title":"Epidemiologic and molecular trends of \u201cNorwalk-like viruses\u201d associated with outbreaks of gastroenteritis in the United States.","volume":"186","author":"Fankhauser","year":"2002","journal-title":"J Infect Dis."},{"issue":"Suppl 2","key":"10.3945\/jn.110.132134_bib13","doi-asserted-by":"crossref","first-page":"S275","DOI":"10.1086\/315585","article-title":"Epidemiology of calicivirus infections in Sweden, 1994\u20131998.","volume":"181","author":"Hedlund","year":"2000","journal-title":"J Infect Dis."},{"key":"10.3945\/jn.110.132134_bib14","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1002\/(SICI)1096-9071(200005)61:1<117::AID-JMV19>3.0.CO;2-N","article-title":"Seroprevalence and seroincidence of Norwalk-like virus infection among Brazilian infants and children.","volume":"61","author":"Talal","year":"2000","journal-title":"J Med Virol."},{"key":"10.3945\/jn.110.132134_bib15","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1002\/jmv.20084","article-title":"Human astrovirus, norovirus (GI, GII), and sapovirus infections in Pakistani children with diarrhea.","volume":"73","author":"Phan","year":"2004","journal-title":"J Med Virol."},{"key":"10.3945\/jn.110.132134_bib16","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/S0928-8244(01)00310-8","article-title":"Incidence of Norwalk-like viruses, rotavirus and adenovirus infection in patients with acute gastroenteritis in Jakarta, Indonesia.","volume":"33","author":"Subekti","year":"2002","journal-title":"FEMS Immunol Med Microbiol."},{"key":"10.3945\/jn.110.132134_bib17","doi-asserted-by":"crossref","first-page":"2997","DOI":"10.1128\/JCM.00065-06","article-title":"symptomatic norovirus infection in Mexican children.","volume":"44","author":"Garcia","year":"2006","journal-title":"J Clin Microbiol."},{"key":"10.3945\/jn.110.132134_bib18","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1007\/s007050050020","article-title":"Genetic polymorphism across regions of the three open reading frames of \u201cNorwalk-like viruses\u201d.","volume":"145","author":"Vinje","year":"2000","journal-title":"Arch Virol."},{"key":"10.3945\/jn.110.132134_bib19","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1128\/CMR.14.1.15-37.2001","article-title":"Diagnosis of noncultivatable gastroenteritis viruses, the human caliciviruses.","volume":"14","author":"Atmar","year":"2001","journal-title":"Clin Microbiol Rev."},{"key":"10.3945\/jn.110.132134_bib20","doi-asserted-by":"crossref","first-page":"2900","DOI":"10.1128\/JVI.79.5.2900-2909.2005","article-title":"Cellular and humoral immunity following Snow Mountain virus challenge.","volume":"79","author":"Lindesmith","year":"2005","journal-title":"J Virol."},{"key":"10.3945\/jn.110.132134_bib21","doi-asserted-by":"crossref","first-page":"978","DOI":"10.1086\/521195","article-title":"Vitamin A supplementation has divergent effects on norovirus infections and clinical symptoms among Mexican children.","volume":"196","author":"Long","year":"2007","journal-title":"J Infect Dis."},{"key":"10.3945\/jn.110.132134_bib22","doi-asserted-by":"crossref","first-page":"6126","DOI":"10.1128\/JCM.43.12.6126-6129.2005","article-title":"Noroviruses as a cause of traveler's diarrhea among students from the United States visiting Mexico.","volume":"43","author":"Ko","year":"2005","journal-title":"J Clin Microbiol."},{"key":"10.3945\/jn.110.132134_bib23","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/S0166-0934(01)00404-9","article-title":"Genogroup-specific PCR primers for detection of Norwalk-like viruses.","volume":"100","author":"Kojima","year":"2002","journal-title":"J Virol Methods."},{"key":"10.3945\/jn.110.132134_bib24","doi-asserted-by":"crossref","first-page":"127","DOI":"10.3201\/eid0901.010507","article-title":"Single multiplex polymerase chain reaction to detect diverse loci associated with diarrheagenic Escherichia coli.","volume":"9","author":"Lopez-Saucedo","year":"2003","journal-title":"Emerg Infect Dis."},{"key":"10.3945\/jn.110.132134_bib25","doi-asserted-by":"crossref","first-page":"1365","DOI":"10.1093\/jn\/136.5.1365","article-title":"The impact of vitamin A supplementation on the intestinal immune response in Mexican children is modified by pathogen infections and diarrhea.","volume":"136","author":"Long","year":"2006","journal-title":"J Nutr."},{"key":"10.3945\/jn.110.132134_bib26","doi-asserted-by":"crossref","first-page":"1685","DOI":"10.1002\/sim.4780111304","article-title":"Repeated measures in clinical trials: analysis using mean summary statistics and it implication for design.","volume":"11","author":"Frison","year":"1992","journal-title":"Stat Med."},{"key":"10.3945\/jn.110.132134_bib27","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1016\/S1521-6616(03)00120-7","article-title":"Humoral, mucosal, and cellular immune responses to oral Norwalk virus-like particles in volunteers.","volume":"108","author":"Tacket","year":"2003","journal-title":"Clin Immunol."},{"key":"10.3945\/jn.110.132134_bib28","doi-asserted-by":"crossref","first-page":"825","DOI":"10.1002\/jmv.20630","article-title":"Fecal cytokines and markers of intestinal inflammation in international travelers with diarrhea due to noroviruses.","volume":"78","author":"Ko","year":"2006","journal-title":"J Med Virol."},{"key":"10.3945\/jn.110.132134_bib29","doi-asserted-by":"crossref","unstructured":"Chachu KA, LoBue AD, Strong DW, Baric RS, Virgin HW. Immune mechanisms responsible for vaccination against and clearance of mucosal and lymphatic norovirus infection. PLoS Pathog. Epub 2008 Dec 12.","DOI":"10.1371\/journal.ppat.1000236"},{"key":"10.3945\/jn.110.132134_bib30","doi-asserted-by":"crossref","first-page":"1055","DOI":"10.1096\/fasebj.8.13.7926371","article-title":"Monocyte chemotactic proteins MCP-1, MCP-2, and MCP-3 are major attractants for human CD4+ and CD8+ T lymphocytes.","volume":"8","author":"Loetscher","year":"1994","journal-title":"FASEB J."},{"key":"10.3945\/jn.110.132134_bib31","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1016\/0167-7799(96)80920-6","article-title":"Chemokines: progress toward identifying molecular targets for therapeutic agents.","volume":"14","author":"Howard","year":"1996","journal-title":"Trends Biotechnol."},{"key":"10.3945\/jn.110.132134_bib32","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/0167-5699(90)90035-8","article-title":"Human monocyte chemoattractant protein-1.","volume":"11","author":"Leonard","year":"1990","journal-title":"Immunol Today."},{"key":"10.3945\/jn.110.132134_bib33","doi-asserted-by":"crossref","first-page":"2423","DOI":"10.4049\/jimmunol.148.8.2423","article-title":"Monocyte chemoattractant protein-1 regulates adhesion molecule expression and cytokine production in human monocytes.","volume":"148","author":"Jiang","year":"1992","journal-title":"J Immunol."},{"key":"10.3945\/jn.110.132134_bib34","doi-asserted-by":"crossref","first-page":"4861","DOI":"10.4049\/jimmunol.169.9.4861","article-title":"Monocyte chemoattractant protein-1 selectively inhibits the acquisition of CD40 ligand-dependent IL-12-producing capacity of monocyte-derived dendritic cells and modulates Th1 immune response.","volume":"169","author":"Omata","year":"2002","journal-title":"J Immunol."},{"key":"10.3945\/jn.110.132134_bib35","doi-asserted-by":"crossref","first-page":"4659","DOI":"10.4049\/jimmunol.168.9.4659","article-title":"Differential roles of CC chemokine ligand 2\/monocyte chemotactic protein-1 and CCR2 in the development of Th1 immunity.","volume":"168","author":"Traynor","year":"2002","journal-title":"J Immunol."},{"key":"10.3945\/jn.110.132134_bib36","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/0014-5793(92)80909-Z","article-title":"Interleukin-8, a chemotactic and inflammatory cytokine.","volume":"307","author":"Baggiolini","year":"1992","journal-title":"FEBS Lett."},{"key":"10.3945\/jn.110.132134_bib37","doi-asserted-by":"crossref","first-page":"9183","DOI":"10.1128\/JVI.00558-07","article-title":"Cytokine and antibody responses in Gnotobiotic pigs after infection with human norovirus genogroup II.4 (HS66 strain).","volume":"81","author":"Souza","year":"2007","journal-title":"J Virol."},{"key":"10.3945\/jn.110.132134_bib38","doi-asserted-by":"crossref","first-page":"959","DOI":"10.1189\/jlb.0109006","article-title":"All-trans retinoic acid down-regulates inflammatory responses by shifting the Treg\/Th17 profile in human ulcerative and murine colitis.","volume":"86","author":"Bai","year":"2009","journal-title":"J Leukoc Biol."},{"key":"10.3945\/jn.110.132134_bib39","doi-asserted-by":"crossref","first-page":"2600","DOI":"10.1093\/jn\/136.10.2600","article-title":"Vitamin A supplementation reduces the monocyte chemoattractant protein-1 intestinal immune response of Mexican children.","volume":"136","author":"Long","year":"2006","journal-title":"J Nutr."},{"key":"10.3945\/jn.110.132134_bib40","doi-asserted-by":"crossref","first-page":"1515","DOI":"10.4049\/jimmunol.152.4.1515","article-title":"In vitamin A deficiency multiple mechanisms establish a regulatory T helper cell imbalance with excess Th1 and insufficient Th2 function.","volume":"152","author":"Cantorna","year":"1994","journal-title":"J Immunol."},{"key":"10.3945\/jn.110.132134_bib41","doi-asserted-by":"crossref","first-page":"1132","DOI":"10.1093\/jn\/130.5.1132","article-title":"High level dietary vitamin A enhances T-helper type 2 cytokine production and secretory immunoglobulin A response to influenza A virus infection in BALB\/c mice.","volume":"130","author":"Cui","year":"2000","journal-title":"J Nutr."},{"key":"10.3945\/jn.110.132134_bib42","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1086\/367809","article-title":"Homologous versus heterologous immune responses to Norwalk-like viruses among crew members after acute gastroenteritis outbreaks on 2 US Navy vessels.","volume":"187","author":"Farkas","year":"2003","journal-title":"J Infect Dis."},{"key":"10.3945\/jn.110.132134_bib43","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1002\/jmv.20473","article-title":"Characterization of the homo- and heterotypic immune responses after natural norovirus infection.","volume":"77","author":"Rockx","year":"2005","journal-title":"J Med Virol."},{"key":"10.3945\/jn.110.132134_bib44","doi-asserted-by":"crossref","first-page":"1800","DOI":"10.1128\/JVI.02179-09","article-title":"Heterotypic humoral and cellular immune responses following Norwalk virus infection.","volume":"84","author":"Lindesmith","year":"2010","journal-title":"J Virol."},{"key":"10.3945\/jn.110.132134_bib45","first-page":"12","article-title":"The great vitamin A fiasco.","volume":"1","author":"Latham","year":"2010","journal-title":"World Nutrition."},{"key":"10.3945\/jn.110.132134_bib46","first-page":"211","article-title":"Vitamin A saves lives. Sound science, sound policy.","volume":"1","author":"West","year":"2010","journal-title":"World Nutrition."}],"container-title":["The Journal of Nutrition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S002231662202569X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S002231662202569X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/academic.oup.com\/jn\/article-pdf\/141\/5\/957\/23950708\/957.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,6,13]],"date-time":"2023-06-13T22:31:57Z","timestamp":1686695517000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S002231662202569X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,5]]},"references-count":46,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2011,5]]}},"alternative-id":["S002231662202569X"],"URL":"https:\/\/doi.org\/10.3945\/jn.110.132134","relation":{},"ISSN":["0022-3166"],"issn-type":[{"value":"0022-3166","type":"print"}],"subject":[],"published":{"date-parts":[[2011,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Vitamin A Modifies the Intestinal Chemokine and Cytokine Responses to Norovirus Infection in Mexican Children1,2","name":"articletitle","label":"Article Title"},{"value":"The Journal of Nutrition","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.3945\/jn.110.132134","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2011 American Society for Nutrition. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}