{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T21:42:00Z","timestamp":1792532520350,"version":"4.5.0"},"reference-count":33,"publisher":"Elsevier BV","issue":"7","license":[{"start":{"date-parts":[[2014,7,1]],"date-time":"2014-07-01T00:00:00Z","timestamp":1404172800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,1,30]],"date-time":"2023-01-30T00:00:00Z","timestamp":1675036800000},"content-version":"vor","delay-in-days":3135,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Nutrition"],"published-print":{"date-parts":[[2014,7]]},"DOI":"10.3945\/jn.113.189480","type":"journal-article","created":{"date-parts":[[2014,4,18]],"date-time":"2014-04-18T06:04:20Z","timestamp":1397801060000},"page":"1037-1042","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":66,"title":["Dietary Intake of Advanced Glycation End Products Did Not Affect Endothelial Function and Inflammation in Healthy Adults in a Randomized Controlled Trial"],"prefix":"10.1016","volume":"144","author":[{"given":"Richard D.","family":"Semba","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah K.","family":"Gebauer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David J.","family":"Baer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kai","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Randi","family":"Turner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Harry A.","family":"Silber","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sameera","family":"Talegawkar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luigi","family":"Ferrucci","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Janet A.","family":"Novotny","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.3945\/jn.113.189480_bib1","doi-asserted-by":"crossref","first-page":"963","DOI":"10.1093\/gerona\/glq074","article-title":"Does accumulation of advanced glycation end products contribute to the aging phenotype?","volume":"65","author":"Semba","year":"2010","journal-title":"J Gerontol A Biol Sci Med Sci."},{"key":"10.3945\/jn.113.189480_bib2","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1196\/annals.1433.030","article-title":"Determination of N\u03b5-(carboxymethyl)lysine in foods and related systems.","volume":"1126","author":"Ames","year":"2008","journal-title":"Ann N Y Acad Sci."},{"key":"10.3945\/jn.113.189480_bib3","doi-asserted-by":"crossref","first-page":"582","DOI":"10.1016\/j.cardiores.2004.05.001","article-title":"Advanced glycation end products and vascular inflammation: implications for accelerated atherosclerosis in diabetes.","volume":"63","author":"Basta","year":"2004","journal-title":"Cardiovasc Res."},{"key":"10.3945\/jn.113.189480_bib4","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.atherosclerosis.2007.07.025","article-title":"Receptor for advanced glycation endproducts and atherosclerosis: from basic mechanisms to clinical implications.","volume":"196","author":"Basta","year":"2008","journal-title":"Atherosclerosis"},{"key":"10.3945\/jn.113.189480_bib5","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1161\/01.HYP.0000164574.60279.ba","article-title":"Advanced glycation end products are associated with pulse pressure in type 1 diabetes: the EURODIAB Prospective Complications Study.","volume":"46","author":"Schram","year":"2005","journal-title":"Hypertension"},{"key":"10.3945\/jn.113.189480_bib6","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1186\/1475-2840-8-45","article-title":"Association between carotid diameter and the advanced glycation end product N-epsilon-carboxymethyllysine (CML).","volume":"8","author":"Baumann","year":"2009","journal-title":"Cardiovasc Diabetol."},{"key":"10.3945\/jn.113.189480_bib7","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1038\/ajh.2008.320","article-title":"Serum carboxymethyl-lysine, an advanced glycation end product, is associated with increased aortic pulse wave velocity in adults.","volume":"22","author":"Semba","year":"2009","journal-title":"Am J Hypertens."},{"key":"10.3945\/jn.113.189480_bib8","doi-asserted-by":"crossref","first-page":"1409","DOI":"10.1007\/s00125-007-0687-z","article-title":"Increased serum levels of advanced glycation end products predict total, cardiovascular and coronary mortality in women with type 2 diabetes: a population-based 18 year follow-up study.","volume":"50","author":"Kilhovd","year":"2007","journal-title":"Diabetologia"},{"key":"10.3945\/jn.113.189480_bib9","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1007\/BF03325227","article-title":"Advanced glycation end products and their circulating receptors predict cardiovascular disease mortality in older community-dwelling women.","volume":"21","author":"Semba","year":"2009","journal-title":"Aging Clin Exp Res."},{"key":"10.3945\/jn.113.189480_bib10","doi-asserted-by":"crossref","first-page":"1874","DOI":"10.1111\/j.1532-5415.2009.02438.x","article-title":"Plasma carboxymethyl-lysine, and advanced glycation end product, and all-cause and cardiovascular disease mortality in older community-dwelling adults.","volume":"57","author":"Semba","year":"2009","journal-title":"J Am Geriatr Soc."},{"key":"10.3945\/jn.113.189480_bib11","doi-asserted-by":"crossref","first-page":"1069","DOI":"10.1002\/mnfr.200790016","article-title":"Special issue: Are dietary AGEs\/ALEs a health risk?","volume":"51","author":"Pischetsrieder","year":"2007","journal-title":"Mol Nutr Food Res."},{"key":"10.3945\/jn.113.189480_bib12","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1038\/ejcn.2012.220","article-title":"Dietary advanced glycation end-product restriction for the attenuation of insulin resistance, oxidative stress and endothelial dysfunction: a systematic review.","volume":"67","author":"Kellow","year":"2013","journal-title":"Eur J Clin Nutr."},{"key":"10.3945\/jn.113.189480_bib13","doi-asserted-by":"crossref","first-page":"6474","DOI":"10.1073\/pnas.94.12.6474","article-title":"Orally absorbed reactive glycation products (glycotoxins): an environmental risk factor in diabetic nephropathy.","volume":"94","author":"Koschinsky","year":"1997","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.3945\/jn.113.189480_bib14","doi-asserted-by":"crossref","first-page":"1236","DOI":"10.1093\/ajcn\/85.5.1236","article-title":"Effects of low- and high-advanced glycation endproduct meals on macro- and microvascular endothelial function and oxidative stress in patients with type 2 diabetes mellitus.","volume":"85","author":"Negrean","year":"2007","journal-title":"Am J Clin Nutr."},{"key":"10.3945\/jn.113.189480_bib15","doi-asserted-by":"crossref","first-page":"2579","DOI":"10.2337\/dc07-0320","article-title":"Single oral challenge by advanced glycation end products acutely impairs endothelial function in diabetic and nondiabetic subjects.","volume":"30","author":"Uribarri","year":"2007","journal-title":"Diabetes Care"},{"key":"10.3945\/jn.113.189480_bib16","doi-asserted-by":"crossref","first-page":"15596","DOI":"10.1073\/pnas.242407999","article-title":"Inflammatory mediators are induced by dietary glycotoxins, a major risk factor for diabetic angiopathy.","volume":"99","author":"Vlassara","year":"2002","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.3945\/jn.113.189480_bib17","doi-asserted-by":"crossref","first-page":"1220","DOI":"10.3945\/ajcn.2009.28737","article-title":"A diet based on high-heat-treated foods promotes risk factors for diabetes mellitus and cardiovascular diseases.","volume":"91","author":"Birlouez-Aragon","year":"2010","journal-title":"Am J Clin Nutr."},{"key":"10.3945\/jn.113.189480_bib18","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1159\/000217817","article-title":"Short-term low calorie diet intervention reduces serum advanced glycation end products in healthy overweight or obese adults.","volume":"54","author":"Gugliucci","year":"2009","journal-title":"Ann Nutr Metab."},{"key":"10.3945\/jn.113.189480_bib19","first-page":"PH65","article-title":"Decrease in serum levels of advanced glycation end-products by short-term lifestyle modification in non-diabetic middle-aged females.","volume":"15","author":"Yoshikawa","year":"2009","journal-title":"Med Sci Monit."},{"key":"10.3945\/jn.113.189480_bib20","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/0022-3956(75)90026-6","article-title":"\u201cMini-mental state.\u201d A practical method for grading the cognitive state of patients for the clinician.","volume":"12","author":"Folstein","year":"1975","journal-title":"J Psychiatr Res."},{"key":"10.3945\/jn.113.189480_bib21","doi-asserted-by":"crossref","first-page":"482","DOI":"10.1016\/j.exger.2011.02.001","article-title":"Pyridoxamine prevents age-related aortic stiffening and vascular resistance in association with reduced collagen glycation.","volume":"46","author":"Wu","year":"2011","journal-title":"Exp Gerontol."},{"key":"10.3945\/jn.113.189480_bib22","doi-asserted-by":"crossref","first-page":"1287","DOI":"10.1016\/j.jada.2004.05.214","article-title":"Advanced glycoxidation end products in commonly consumed foods.","volume":"104","author":"Goldberg","year":"2004","journal-title":"J Am Diet Assoc."},{"key":"10.3945\/jn.113.189480_bib23","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1016\/j.tcm.2009.03.001","article-title":"Assessment of endothelial function using digital pulse amplitude tonometry.","volume":"19","author":"Hamburg","year":"2009","journal-title":"Trends Cardiovasc Med."},{"key":"10.3945\/jn.113.189480_bib24","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1515\/CCLM.2005.089","article-title":"Two immunochemical assays to measure advanced glycation end-products in serum from dialysis patients.","volume":"43","author":"Zhang","year":"2005","journal-title":"Clin Chem Lab Med."},{"key":"10.3945\/jn.113.189480_bib25","doi-asserted-by":"crossref","first-page":"1376","DOI":"10.1007\/s00125-004-1455-y","article-title":"Elevated serum levels of N\u03b5-carboymethyl-lysine, an advanced glycation end product, are associated with proliferative diabetic retinopathy and macular oedema.","volume":"47","author":"Boehm","year":"2004","journal-title":"Diabetologia"},{"key":"10.3945\/jn.113.189480_bib26","doi-asserted-by":"crossref","first-page":"1379","DOI":"10.1093\/clinchem\/28.6.1379","article-title":"Dextran sulfate-Mg2+ precipitation procedure for quantification of high-density-lipoprotein cholesterol.","volume":"28","author":"Warnick","year":"1982","journal-title":"Clin Chem."},{"key":"10.3945\/jn.113.189480_bib27","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1093\/clinchem\/18.6.499","article-title":"Estimation of the concentration of low-density-lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge.","volume":"18","author":"Friedewald","year":"1972","journal-title":"Clin Chem."},{"key":"10.3945\/jn.113.189480_bib28","doi-asserted-by":"crossref","first-page":"2467","DOI":"10.1161\/CIRCULATIONAHA.107.748574","article-title":"Cross-sectional relations of digital vascular function to cardiovascular risk factors in the Framingham Heart Study.","volume":"117","author":"Hamburg","year":"2008","journal-title":"Circulation"},{"key":"10.3945\/jn.113.189480_bib29","doi-asserted-by":"crossref","first-page":"1726","DOI":"10.3945\/jn.111.143172","article-title":"Fat mass is inversely associated with serum carboxymethyl-lysine, an advanced glycation end product, in adults.","volume":"141","author":"Semba","year":"2011","journal-title":"J Nutr."},{"key":"10.3945\/jn.113.189480_bib30","doi-asserted-by":"crossref","first-page":"1712","DOI":"10.1006\/cyto.2000.0764","article-title":"Effects of sample handling on the stability of interleukin 6, tumour necrosis factor-alpha and leptin.","volume":"12","author":"Flower","year":"2000","journal-title":"Cytokine"},{"key":"10.3945\/jn.113.189480_bib31","doi-asserted-by":"crossref","first-page":"e55477","DOI":"10.1371\/journal.pone.0055477","article-title":"Soluble TNF receptors are associated with infarct size and ventricular dysfunction in ST-elevation myocardial infarction.","volume":"8","author":"Nilsson","year":"2013","journal-title":"PLoS One"},{"key":"10.3945\/jn.113.189480_bib32","doi-asserted-by":"crossref","first-page":"474","DOI":"10.1196\/annals.1333.054","article-title":"Studies on absorption and elimination of dietary Maillard reaction products.","volume":"1043","author":"F\u00f6rster","year":"2005","journal-title":"Ann N Y Acad Sci."},{"key":"10.3945\/jn.113.189480_bib33","doi-asserted-by":"crossref","first-page":"1032","DOI":"10.1039\/c3fo30351a","article-title":"Metabolic transit ofN\u03b5-carboxymethyl-lysine after consumption of AGEs from bread crust.","volume":"4","author":"Roncero-Ramos","year":"2013","journal-title":"Food Funct."}],"container-title":["The Journal of Nutrition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022316622009312?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022316622009312?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/academic.oup.com\/jn\/article-pdf\/144\/7\/1037\/23977228\/1037.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,6,13]],"date-time":"2023-06-13T21:51:54Z","timestamp":1686693114000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022316622009312"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,7]]},"references-count":33,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2014,7]]}},"alternative-id":["S0022316622009312"],"URL":"https:\/\/doi.org\/10.3945\/jn.113.189480","relation":{},"ISSN":["0022-3166"],"issn-type":[{"value":"0022-3166","type":"print"}],"subject":[],"published":{"date-parts":[[2014,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Dietary Intake of Advanced Glycation End Products Did Not Affect Endothelial Function and Inflammation in Healthy Adults in a Randomized Controlled Trial","name":"articletitle","label":"Article Title"},{"value":"The Journal of Nutrition","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.3945\/jn.113.189480","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2014 American Society for Nutrition. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}