{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T04:38:20Z","timestamp":1788410300520,"version":"build-2803163510"},"reference-count":39,"publisher":"Elsevier BV","issue":"7","license":[{"start":{"date-parts":[[2016,7,1]],"date-time":"2016-07-01T00:00:00Z","timestamp":1467331200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,1,30]],"date-time":"2023-01-30T00:00:00Z","timestamp":1675036800000},"content-version":"vor","delay-in-days":2404,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"name":"Nestle Nutrition Institute"},{"DOI":"10.13039\/501100003653","name":"NIH","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003653","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000199","name":"USDA","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000199","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007822","name":"Almond Board of California","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007822","id-type":"DOI","asserted-by":"publisher"}]},{"name":"California Walnut Commission"},{"name":"Harvest Plus"},{"name":"Nestle Foundation"},{"DOI":"10.13039\/100000865","name":"Bill & Melinda Gates Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000865","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100005977","name":"Kaiser Permanente","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100005977","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Nutrition"],"published-print":{"date-parts":[[2016,7]]},"DOI":"10.3945\/jn.115.223420","type":"journal-article","created":{"date-parts":[[2016,6,9]],"date-time":"2016-06-09T19:37:32Z","timestamp":1465501052000},"page":"1445S-1452S","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":60,"title":["Neither Preconceptional Weekly Multiple Micronutrient nor Iron\u2013Folic Acid Supplements Affect Birth Size and Gestational Age Compared with a Folic Acid Supplement Alone in Rural Vietnamese Women: A Randomized Controlled Trial"],"prefix":"10.1016","volume":"146","author":[{"given":"Usha","family":"Ramakrishnan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Phuong H","family":"Nguyen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ines","family":"Gonzalez-Casanova","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hoa","family":"Pham","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Hao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hieu","family":"Nguyen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Truong V","family":"Truong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Son","family":"Nguyen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kimberly B","family":"Harding","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gregory A","family":"Reinhart","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lynnette M","family":"Neufeld","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Reynaldo","family":"Martorell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.3945\/jn.115.223420_bib1","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1016\/S0140-6736(13)60937-X","article-title":"Maternal and child undernutrition and overweight in low-income and middle-income countries","volume":"382","author":"Black","year":"2013","journal-title":"Lancet"},{"issue":"Suppl 1","key":"10.3945\/jn.115.223420_bib2","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1111\/j.1365-3016.2012.01281.x","article-title":"Effect of women\u2019s nutrition before and during early pregnancy on maternal and infant outcomes: a systematic review","volume":"26","author":"Ramakrishnan","year":"2012","journal-title":"Paediatr Perinat Epidemiol"},{"key":"10.3945\/jn.115.223420_bib3","doi-asserted-by":"crossref","first-page":"1340","DOI":"10.1017\/S1368980012004417","article-title":"Dietary intakes of women during pregnancy in low- and middle-income countries","volume":"16","author":"Lee","year":"2013","journal-title":"Public Health Nutr"},{"issue":"Suppl 3","key":"10.3945\/jn.115.223420_bib4","doi-asserted-by":"crossref","first-page":"S3","DOI":"10.1186\/1742-4755-11-S3-S3","article-title":"Preconception care: nutritional risks and interventions","volume":"11","author":"Dean","year":"2014","journal-title":"Reprod Health"},{"key":"10.3945\/jn.115.223420_bib5","doi-asserted-by":"crossref","first-page":"1218S","DOI":"10.1093\/ajcn\/71.5.1218s","article-title":"Physiology of pregnancy and nutrient metabolism","volume":"71","author":"King","year":"2000","journal-title":"Am J Clin Nutr"},{"key":"10.3945\/jn.115.223420_bib6","series-title":"J Nutr","first-page":"1437S","article-title":"A summary of pathways or mechanisms linking preconception maternal nutrition with birth outcomes","author":"King","year":"2016"},{"key":"10.3945\/jn.115.223420_bib7","series-title":"Cochrane Database Syst Rev","first-page":"CD007950","article-title":"Effects and safety of periconceptional folate supplementation for preventing birth defects","author":"De-Regil","year":"2010"},{"key":"10.3945\/jn.115.223420_bib8","series-title":"Cochrane Database Syst Rev","first-page":"CD001056","article-title":"Periconceptional supplementation with folate and\/or multivitamins for preventing neural tube defects","author":"Lumley","year":"2001"},{"issue":"Suppl 2","key":"10.3945\/jn.115.223420_bib9","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1111\/j.1740-8709.2010.00269.x","article-title":"Critical issues in setting micronutrient recommendations for pregnant women: an insight","volume":"6","author":"Berti","year":"2010","journal-title":"Matern Child Nutr"},{"issue":"Suppl 1","key":"10.3945\/jn.115.223420_bib10","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1111\/j.1365-3016.2012.01276.x","article-title":"Effect of multiple micronutrient supplementation on pregnancy and infant outcomes: a systematic review","volume":"26","author":"Ramakrishnan","year":"2012","journal-title":"Paediatr Perinat Epidemiol"},{"key":"10.3945\/jn.115.223420_bib11","series-title":"Cochrane Database Syst Rev","first-page":"CD009218","article-title":"Intermittent iron supplementation for reducing anaemia and its associated impairments in menstruating women","author":"Fern\u00e1ndez-Gaxiola","year":"2011"},{"key":"10.3945\/jn.115.223420_bib12","series-title":"Intermittent iron and folic acid supplementation in menstruating women","year":"2011"},{"key":"10.3945\/jn.115.223420_bib13","doi-asserted-by":"crossref","first-page":"898","DOI":"10.1186\/1471-2458-12-898","article-title":"Rationale, design, methodology and sample characteristics for the Vietnam pre-conceptual micronutrient supplementation trial (PRECONCEPT): a randomized controlled study","volume":"12","author":"Nguyen","year":"2012","journal-title":"BMC Public Health"},{"key":"10.3945\/jn.115.223420_bib14","doi-asserted-by":"crossref","first-page":"e89504","DOI":"10.1371\/journal.pone.0089504","article-title":"Micronutrient intakes among women of reproductive age in Vietnam","volume":"9","author":"Nguyen","year":"2014","journal-title":"PLoS One"},{"key":"10.3945\/jn.115.223420_bib15","series-title":"Dietary reference intakes: the essential guide to nutrient requirements","author":"Otten","year":"2006"},{"key":"10.3945\/jn.115.223420_bib16","series-title":"Prevention and control. A guide for programme managers","year":"2001"},{"key":"10.3945\/jn.115.223420_bib17","series-title":"Statistical power for the behavioral sciences","author":"Cohen","year":"1988"},{"key":"10.3945\/jn.115.223420_bib18","series-title":"Anthropometric standardization reference manual","author":"Lohman","year":"1988"},{"key":"10.3945\/jn.115.223420_bib19","series-title":"Anthropometric indicators measurement guide","author":"Cogill","year":"2003"},{"key":"10.3945\/jn.115.223420_bib20","series-title":"Principles of Nutritional Assessment","author":"Gibson","year":"2005"},{"key":"10.3945\/jn.115.223420_bib21","doi-asserted-by":"crossref","first-page":"857","DOI":"10.1016\/S0140-6736(14)60932-6","article-title":"International standards for newborn weight, length, and head circumference by gestational age and sex: the Newborn Cross-Sectional Study of the INTERGROWTH-21st Project","volume":"384","author":"Villar","year":"2014","journal-title":"Lancet"},{"key":"10.3945\/jn.115.223420_bib22","unstructured":"Hemocue [Internet]. Hemocue Hb301 2012 [cited 2015 Aug 10]. Available from: http:\/\/www.hemocue.com\/international\/Products\/Hemoglobin-1155.html."},{"key":"10.3945\/jn.115.223420_bib23","unstructured":"Benoist BD, McLean E, Egli I, Cogswell M. Worldwide prevalence of anaemia 1993\u20132005. In.: WHO Global database on anemia; 2008."},{"key":"10.3945\/jn.115.223420_bib24","unstructured":"WHO 2011 [Internet]. Haemoglobin concentrations for the diagnosis of anaemia and assessment of severity [cited 2015 Aug 10]. Available from: http:\/\/www.who.int\/vmnis\/indicators\/haemoglobin."},{"key":"10.3945\/jn.115.223420_bib25","doi-asserted-by":"crossref","first-page":"3127","DOI":"10.1093\/jn\/134.11.3127","article-title":"Combined measurement of ferritin, soluble transferrin receptor, retinol binding protein, and C-reactive protein by an inexpensive, sensitive, and simple sandwich enzyme-linked immunosorbent assay technique","volume":"134","author":"Erhardt","year":"2004","journal-title":"J Nutr"},{"key":"10.3945\/jn.115.223420_bib26","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1111\/j.1365-2796.1989.tb01408.x","article-title":"Iron deficiency: definition and diagnosis","volume":"226","author":"Cook","year":"1989","journal-title":"J Intern Med"},{"key":"10.3945\/jn.115.223420_bib27","doi-asserted-by":"crossref","DOI":"10.1155\/2014\/605810","article-title":"C-reactive protein: clinical and epidemiological perspectives","volume":"2014","author":"Salazar","year":"2014","journal-title":"Cardiol Res Pract"},{"key":"10.3945\/jn.115.223420_bib28","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1016\/j.annepidem.2009.12.003","article-title":"Periconceptional multivitamin use and infant birth weight disparities","volume":"20","author":"Burris","year":"2010","journal-title":"Ann Epidemiol"},{"key":"10.3945\/jn.115.223420_bib29","doi-asserted-by":"crossref","first-page":"906","DOI":"10.3945\/ajcn.111.012393","article-title":"Periconceptional multivitamin use and risk of preterm or small-for-gestational-age births in the Danish National Birth Cohort","volume":"94","author":"Catov","year":"2011","journal-title":"Am J Clin Nutr"},{"key":"10.3945\/jn.115.223420_bib30","doi-asserted-by":"crossref","unstructured":"Obeid R, Oexle K, Rissmann A, Pietrzik K, Koletzko B. Folate status and health: challenges and opportunities. J Perinat Med 2015 Feb 6. (Epub ahead of print; DOI: 10.1155\/2014\/605810).","DOI":"10.1515\/jpm-2014-0346"},{"key":"10.3945\/jn.115.223420_bib31","first-page":"CD004736","article-title":"Daily oral iron supplementation during pregnancy","volume":"7","author":"Pe\u00f1a-Rosas","year":"2015","journal-title":"Cochrane Database Syst Rev"},{"issue":"Supplement 729","key":"10.3945\/jn.115.223420_bib32","first-page":"712","article-title":"Predictors of adherence to preconception and prenatal micronutrient supplementation in Vietnam","volume":"29","author":"Gonzalez-Casanova","year":"2015","journal-title":"The FASEB Journal"},{"key":"10.3945\/jn.115.223420_bib33","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1038\/ejcn.2014.181","article-title":"Multicausal etiology of anemia among women of reproductive age in Vietnam","volume":"69","author":"Nguyen","year":"2015","journal-title":"Eur J Clin Nutr"},{"key":"10.3945\/jn.115.223420_bib34","unstructured":"NIN, MOH, UNICEF 2012 [Internet]. Summary Report General Nutrition Survey 2009\u20132010 [cited 2015 Aug 10]. Available from: http:\/\/www.unicef.org\/vietnam\/resources_18459.html."},{"key":"10.3945\/jn.115.223420_bib35","doi-asserted-by":"crossref","first-page":"2607","DOI":"10.1182\/blood-2012-09-453522","article-title":"Control of iron deficiency anemia in low- and middle-income countries","volume":"121","author":"Pasricha","year":"2013","journal-title":"Blood"},{"key":"10.3945\/jn.115.223420_bib36","doi-asserted-by":"crossref","first-page":"1257","DOI":"10.3945\/ajcn.114.084921","article-title":"Improving women\u2019s diet quality preconceptionally and during gestation: effects on birth weight and prevalence of low birth weight\u2013a randomized controlled efficacy trial in India (Mumbai Maternal Nutrition Project)","volume":"100","author":"Potdar","year":"2014","journal-title":"Am J Clin Nutr"},{"key":"10.3945\/jn.115.223420_bib37","doi-asserted-by":"crossref","first-page":"1453S","DOI":"10.3945\/jn.115.223461","article-title":"A daily snack containing leafy green vegetables, fruit, and milk before and during pregnancy prevents gestational diabetes in a randomized, controlled trial in Mumbai, India","volume":"146","author":"Sahariah","year":"2016","journal-title":"J Nutr"},{"key":"10.3945\/jn.115.223420_bib38","doi-asserted-by":"crossref","first-page":"3746","DOI":"10.1038\/ncomms4746","article-title":"Maternal nutrition at conception modulates DNA methylation of human metastable epialleles","volume":"5","author":"Dominguez-Salas","year":"2014","journal-title":"Nat Commun"},{"key":"10.3945\/jn.115.223420_bib39","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1186\/1471-2393-14-111","article-title":"Preconception maternal nutrition: a multi-site randomized controlled trial","volume":"14","author":"Hambidge","year":"2014","journal-title":"BMC Pregnancy Childbirth"}],"container-title":["The Journal of Nutrition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022316623006612?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022316623006612?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/academic.oup.com\/jn\/article-pdf\/146\/7\/1445S\/23969302\/jn223420.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,6,14]],"date-time":"2023-06-14T00:16:13Z","timestamp":1686701773000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022316623006612"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,7]]},"references-count":39,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2016,7]]}},"alternative-id":["S0022316623006612"],"URL":"https:\/\/doi.org\/10.3945\/jn.115.223420","relation":{},"ISSN":["0022-3166"],"issn-type":[{"value":"0022-3166","type":"print"}],"subject":[],"published":{"date-parts":[[2016,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Neither Preconceptional Weekly Multiple Micronutrient nor Iron\u2013Folic Acid Supplements Affect Birth Size and Gestational Age Compared with a Folic Acid Supplement Alone in Rural Vietnamese Women: A Randomized Controlled Trial","name":"articletitle","label":"Article Title"},{"value":"The Journal of Nutrition","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.3945\/jn.115.223420","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2016 American Society for Nutrition. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}