{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,19]],"date-time":"2026-03-19T10:57:44Z","timestamp":1773917864050,"version":"3.50.1"},"reference-count":48,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2016,6,1]],"date-time":"2016-06-01T00:00:00Z","timestamp":1464739200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,2,6]],"date-time":"2023-02-06T00:00:00Z","timestamp":1675641600000},"content-version":"vor","delay-in-days":2441,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/100000071","name":"National Institute of Child Health and Human Development","doi-asserted-by":"publisher","award":["NICHD U01 HD061232"],"award-info":[{"award-number":["NICHD U01 HD061232"]}],"id":[{"id":"10.13039\/100000071","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Nutrition"],"published-print":{"date-parts":[[2016,6]]},"DOI":"10.3945\/jn.115.225482","type":"journal-article","created":{"date-parts":[[2016,4,28]],"date-time":"2016-04-28T16:38:04Z","timestamp":1461861484000},"page":"1162-1171","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":32,"title":["Iron Supplementation Affects Hematologic Biomarker Concentrations and Pregnancy Outcomes among Iron-Deficient Tanzanian Women"],"prefix":"10.1016","volume":"146","author":[{"given":"Ajibola I","family":"Abioye","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Said","family":"Aboud","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zulfiqar","family":"Premji","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Analee J","family":"Etheredge","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nilupa S","family":"Gunaratna","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christopher R","family":"Sudfeld","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert","family":"Mongi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laura","family":"Meloney","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anne Marie","family":"Darling","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ramadhani A","family":"Noor","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Donna","family":"Spiegelman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christopher","family":"Duggan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wafaie","family":"Fawzi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.3945\/jn.115.225482_bib1","doi-asserted-by":"crossref","first-page":"260380","DOI":"10.1155\/2011\/260380","article-title":"Iron deficiency anemia: focus on infectious diseases in lesser developed countries","volume":"2011","author":"Shaw","year":"2011","journal-title":"Anemia"},{"key":"10.3945\/jn.115.225482_bib2","doi-asserted-by":"crossref","first-page":"1280S","DOI":"10.1093\/ajcn\/71.5.1280s","article-title":"Anemia and iron deficiency: effects on pregnancy outcome","volume":"71","author":"Allen","year":"2000","journal-title":"Am J Clin Nutr"},{"key":"10.3945\/jn.115.225482_bib3","doi-asserted-by":"crossref","first-page":"3443","DOI":"10.1136\/bmj.f3443","article-title":"Anaemia, prenatal iron use, and risk of adverse pregnancy outcomes: systematic review and meta-analysis","volume":"346","author":"Haider","year":"2013","journal-title":"BMJ"},{"key":"10.3945\/jn.115.225482_bib4","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1159\/000354932","article-title":"Global distribution and disease burden related to micronutrient deficiencies","volume":"78","author":"Black","year":"2014","journal-title":"Nestle Nutr Inst Workshop Ser"},{"key":"10.3945\/jn.115.225482_bib5","doi-asserted-by":"crossref","first-page":"663","DOI":"10.3945\/jn.114.206078","article-title":"The Global Nutrition Report 2014: actions and accountability to accelerate the world's progress on nutrition","volume":"145","author":"Haddad","year":"2015","journal-title":"J Nutr"},{"key":"10.3945\/jn.115.225482_bib6","doi-asserted-by":"crossref","first-page":"596","DOI":"10.1017\/S1368980007000924","article-title":"Determinants of compliance with iron supplementation among pregnant women in Senegal","volume":"11","author":"Seck","year":"2008","journal-title":"Public Health Nutr"},{"key":"10.3945\/jn.115.225482_bib7","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1186\/1471-2458-14-607","article-title":"Coverage, compliance and factors associated with utilization of iron supplementation during pregnancy in eight rural districts of Ethiopia: a cross-sectional study","volume":"14","author":"Gebremedhin","year":"2014","journal-title":"BMC Public Health"},{"key":"10.3945\/jn.115.225482_bib8","doi-asserted-by":"crossref","first-page":"43","DOI":"10.11604\/pamj.2015.20.43.4894","article-title":"Factors associated with compliance of prenatal iron folate supplementation among women in Mecha district, Western Amhara: a cross-sectional study","volume":"20","author":"Taye","year":"2015","journal-title":"Pan Afr Med J"},{"key":"10.3945\/jn.115.225482_bib9","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1186\/1475-2875-11-249","article-title":"Zinc erythrocyte protoporphyrin as marker of malaria risk in pregnancy-a retrospective cross-sectional and longitudinal study","volume":"11","author":"Senga","year":"2012","journal-title":"Malar J"},{"key":"10.3945\/jn.115.225482_bib10","doi-asserted-by":"crossref","first-page":"S2","DOI":"10.1017\/S000711450800679X","article-title":"Methods to assess iron and iodine status","volume":"99","author":"Zimmermann","year":"2008","journal-title":"Br J Nutr"},{"key":"10.3945\/jn.115.225482_bib11","doi-asserted-by":"crossref","first-page":"5277","DOI":"10.1182\/blood-2008-12-195651","article-title":"Regulation of iron homeostasis in anemia of chronic disease and iron deficiency anemia: diagnostic and therapeutic implications","volume":"113","author":"Theurl","year":"2009","journal-title":"Blood"},{"key":"10.3945\/jn.115.225482_bib12","first-page":"451","article-title":"Hepcidin and iron status among pregnant women in Bangladesh","volume":"17","author":"Schulze","year":"2008","journal-title":"Asia Pac J Clin Nutr"},{"key":"10.3945\/jn.115.225482_bib13","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1007\/s00277-006-0108-2","article-title":"Iron and pregnancy\u2014a delicate balance","volume":"85","author":"Milman","year":"2006","journal-title":"Ann Hematol"},{"key":"10.3945\/jn.115.225482_bib14","series-title":"The national road map strategic plan to accelerate reduction of maternal, newborn and child deaths in Tanzania 2008\u20132015","first-page":"1","article-title":"MOHSW-Tanzania","author":"Mwakyusa","year":"2008"},{"key":"10.3945\/jn.115.225482_bib15","doi-asserted-by":"crossref","first-page":"947","DOI":"10.1001\/jamapediatrics.2015.1480","article-title":"Iron supplementation among iron-replete and non-anemic pregnant women: a randomized placebo-controlled trial in Tanzania","volume":"169","author":"Etheredge","year":"2015","journal-title":"JAMA Pediatr"},{"key":"10.3945\/jn.115.225482_bib16","doi-asserted-by":"crossref","first-page":"3","DOI":"10.5402\/2012\/567491","article-title":"Evaluation of the first commercial hepcidin ELISA for the differential diagnosis of anemia of chronic disease and iron deficiency anemia in hospitalized geriatric patients","volume":"2012","author":"Geerts","year":"2012","journal-title":"ISRN Hematology"},{"key":"10.3945\/jn.115.225482_bib17","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1093\/jn\/138.3.613","article-title":"The influence and benefits of controlling for inflammation on plasma ferritin and hemoglobin responses following a multi-micronutrient supplement in apparently healthy, HIV+ Kenyan adults","volume":"138","author":"Mburu","year":"2008","journal-title":"J Nutr"},{"key":"10.3945\/jn.115.225482_bib18","doi-asserted-by":"crossref","first-page":"1498","DOI":"10.1093\/ajcn\/84.6.1498","article-title":"Interpretation of serum ferritin concentrations as indicators of total-body iron stores in survey populations: the role of biomarkers for the acute phase response","volume":"84","author":"Beard","year":"2006","journal-title":"Am J Clin Nutr"},{"key":"10.3945\/jn.115.225482_bib19","doi-asserted-by":"crossref","first-page":"134","DOI":"10.3945\/jn.114.198945","article-title":"Genetic hemoglobin disorders rather than iron deficiency are a major predictor of hemoglobin concentration in women of reproductive age in rural Prey Veng, Cambodia","volume":"145","author":"Karakochuk","year":"2015","journal-title":"J Nutr"},{"key":"10.3945\/jn.115.225482_bib20","first-page":"33","article-title":"Iron deficiency anemia: assessment, prevention, and control Report No. 013","year":"2001","journal-title":"A guide for programme managers WHO\/NIID"},{"key":"10.3945\/jn.115.225482_bib21","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1002\/sim.2538","article-title":"Revisiting the relation between change and initial value: a review and evaluation","volume":"26","author":"Tu","year":"2007","journal-title":"Stat Med"},{"key":"10.3945\/jn.115.225482_bib22","first-page":"1271","article-title":"Re: Thiamin deficiency and uncomplicated falciparum malaria in Laos Trop Med Int Health","volume":"12","author":"Verhoef","year":"2007"},{"key":"10.3945\/jn.115.225482_bib23","doi-asserted-by":"crossref","first-page":"969","DOI":"10.1016\/0021-9681(62)90116-9","article-title":"A note on the analysis of repeated measurements of the same subjects","volume":"15","author":"Oldham","year":"1962","journal-title":"J Chronic Dis"},{"key":"10.3945\/jn.115.225482_bib24","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1093\/aje\/kwi188","article-title":"Easy SAS calculations for risk or prevalence ratios and differences","volume":"162","author":"Spiegelman","year":"2005","journal-title":"Am J Epidemiol"},{"key":"10.3945\/jn.115.225482_bib25","doi-asserted-by":"crossref","first-page":"857","DOI":"10.1016\/S0140-6736(14)60932-6","article-title":"International standards for newborn weight, length, and head circumference by gestational age and sex: the Newborn Cross-Sectional Study of the INTERGROWTH-21st Project","volume":"384","author":"Villar","year":"2014","journal-title":"Lancet"},{"key":"10.3945\/jn.115.225482_bib26","doi-asserted-by":"crossref","first-page":"702","DOI":"10.1093\/aje\/kwh090","article-title":"A modified poisson regression approach to prospective studies with binary data","volume":"159","author":"Zou","year":"2004","journal-title":"Am J Epidemiol"},{"key":"10.3945\/jn.115.225482_bib27","series-title":"Channing Laboratory","first-page":"1","article-title":"The SAS ROBREG9 Macro","author":"Hertzmark","year":"2010"},{"key":"10.3945\/jn.115.225482_bib28","doi-asserted-by":"crossref","first-page":"1179","DOI":"10.1093\/jn\/124.8.1179","article-title":"Iron, vitamin B-12 and folate status in Mexico: associated factors in men and women and during pregnancy and lactation","volume":"124","author":"Black","year":"1994","journal-title":"J Nutr"},{"key":"10.3945\/jn.115.225482_bib29","doi-asserted-by":"crossref","first-page":"813","DOI":"10.1093\/ajcn\/82.4.813","article-title":"Diet and genetic factors associated with iron status in middle-aged women","volume":"82","author":"Cade","year":"2005","journal-title":"Am J Clin Nutr"},{"key":"10.3945\/jn.115.225482_bib30","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1007\/s00404-013-2739-6","article-title":"Pregnancy risk factors for very premature delivery: what role do hypertension, obesity and diabetes play?","volume":"288","author":"Spiegler","year":"2013","journal-title":"Arch Gynecol Obstet"},{"key":"10.3945\/jn.115.225482_bib31","doi-asserted-by":"crossref","first-page":"1465","DOI":"10.1016\/0002-9378(90)90607-9","article-title":"Antenatal microbiologic and maternal risk factors associated with prematurity","volume":"163","author":"McGregor","year":"1990","journal-title":"Am J Obstet Gynecol"},{"key":"10.3945\/jn.115.225482_bib32","doi-asserted-by":"crossref","first-page":"784","DOI":"10.1111\/j.1440-1754.2012.02536.x","article-title":"Increasing rates of prematurity and epidemiology of late preterm birth","volume":"48","author":"Cheong","year":"2012","journal-title":"J Paediatr Child Health"},{"key":"10.3945\/jn.115.225482_bib33","doi-asserted-by":"crossref","first-page":"108593","DOI":"10.1155\/2014\/108593","article-title":"Prevalence and predictors of maternal anemia during pregnancy in Gondar, Northwest Ethiopia: an institutional based cross-sectional study","volume":"2014","author":"Melku","year":"2014","journal-title":"Anemia"},{"key":"10.3945\/jn.115.225482_bib34","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1620\/tjem.223.223","article-title":"Elevated hemoglobin a2 as a marker for BETA-thalassemia trait in pregnant women","volume":"223","author":"Ou","year":"2011","journal-title":"Tohoku J Exp Med"},{"key":"10.3945\/jn.115.225482_bib35","series-title":"2013 ed: OANDA Corporation; Online currency converter","year":"2013"},{"key":"10.3945\/jn.115.225482_bib36","series-title":"Theoretical epidemiology: principles of occurrence research in medicine","author":"Miettinen","year":"1985"},{"key":"10.3945\/jn.115.225482_bib37","doi-asserted-by":"crossref","first-page":"768","DOI":"10.3945\/ajcn.112.040626","article-title":"Effect of iron intake on iron status: a systematic review and meta-analysis of randomized controlled trials","volume":"96","author":"Casgrain","year":"2012","journal-title":"Am J Clin Nutr"},{"key":"10.3945\/jn.115.225482_bib38","doi-asserted-by":"crossref","first-page":"S3","DOI":"10.1111\/j.1753-4887.2011.00449.x","article-title":"Iron endowment at birth: maternal iron status and other influences","volume":"69","author":"Viteri","year":"2011","journal-title":"Nutr Rev"},{"key":"10.3945\/jn.115.225482_bib39","doi-asserted-by":"crossref","first-page":"e87743","DOI":"10.1371\/journal.pone.0087743","article-title":"The association between malaria and iron status or supplementation in pregnancy: a systematic review and meta-analysis","volume":"9","author":"Sangar\u00e9","year":"2014","journal-title":"PLoS One"},{"key":"10.3945\/jn.115.225482_bib40","doi-asserted-by":"crossref","first-page":"756S","DOI":"10.3945\/jn.110.128793","article-title":"Iron interventions for women and children in low-income countries","volume":"141","author":"Stoltzfus","year":"2011","journal-title":"J Nutr"},{"key":"10.3945\/jn.115.225482_bib41","doi-asserted-by":"crossref","first-page":"a2001","DOI":"10.1136\/bmj.a2001","article-title":"Impact of micronutrient supplementation during pregnancy on birth weight, duration of gestation, and perinatal mortality in rural western China: double blind cluster randomised controlled trial","volume":"337","author":"Zeng","year":"2008","journal-title":"BMJ"},{"key":"10.3945\/jn.115.225482_bib42","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1093\/epirev\/mxq001","article-title":"Maternal nutrition and birth outcomes","volume":"32","author":"Abu-Saad","year":"2010","journal-title":"Epidemiol Rev"},{"key":"10.3945\/jn.115.225482_bib43","first-page":"CD003094","article-title":"Treatments for iron\u2010deficiency anaemia in pregnancy","volume":"2","author":"Reveiz","year":"2007","journal-title":"Cochrane Database Syst Rev"},{"key":"10.3945\/jn.115.225482_bib44","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1016\/S0140-6736(07)61235-5","article-title":"Nutritional iron deficiency","volume":"370","author":"Zimmermann","year":"2007","journal-title":"Lancet"},{"key":"10.3945\/jn.115.225482_bib45","doi-asserted-by":"crossref","first-page":"546","DOI":"10.3945\/ajcn.2010.29284","article-title":"Adjusting plasma ferritin concentrations to remove the effects of subclinical inflammation in the assessment of iron deficiency: a meta-analysis","volume":"92","author":"Thurnham","year":"2010","journal-title":"Am J Clin Nutr"},{"key":"10.3945\/jn.115.225482_bib46","doi-asserted-by":"crossref","first-page":"e0121552","DOI":"10.1371\/journal.pone.0121552","article-title":"Multivitamin and iron supplementation to prevent periconceptional anemia in rural Tanzanian women: a randomized, controlled trial","volume":"10","author":"Gunaratna","year":"2015","journal-title":"PLoS One"},{"key":"10.3945\/jn.115.225482_bib47","doi-asserted-by":"crossref","first-page":"1916","DOI":"10.3945\/jn.114.208678","article-title":"Prenatal Iron Supplementation Reduces Maternal Anemia, Iron Deficiency, and Iron Deficiency Anemia in a Randomized Clinical Trial in Rural China, but Iron Deficiency Remains Widespread in Mothers and Neonates","volume":"145","author":"Zhao","year":"2015","journal-title":"J Nutr"},{"key":"10.3945\/jn.115.225482_bib48","doi-asserted-by":"crossref","first-page":"474","DOI":"10.1007\/s12263-015-0474-2","article-title":"Association of genetic variants with response to iron supplements in pregnancy","volume":"10","author":"Athiyarath","year":"2015","journal-title":"Genes Nutr"}],"container-title":["The Journal of Nutrition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022316623006247?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022316623006247?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/academic.oup.com\/jn\/article-pdf\/146\/6\/1162\/23968110\/jn225482.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,6,14]],"date-time":"2023-06-14T00:14:41Z","timestamp":1686701681000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022316623006247"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,6]]},"references-count":48,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2016,6]]}},"alternative-id":["S0022316623006247"],"URL":"https:\/\/doi.org\/10.3945\/jn.115.225482","relation":{},"ISSN":["0022-3166"],"issn-type":[{"value":"0022-3166","type":"print"}],"subject":[],"published":{"date-parts":[[2016,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Iron Supplementation Affects Hematologic Biomarker Concentrations and Pregnancy Outcomes among Iron-Deficient Tanzanian Women","name":"articletitle","label":"Article Title"},{"value":"The Journal of Nutrition","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.3945\/jn.115.225482","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2016 American Society of Nutrition. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}