{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,3]],"date-time":"2026-07-03T22:38:07Z","timestamp":1783118287081,"version":"3.54.6"},"reference-count":43,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2017,6,1]],"date-time":"2017-06-01T00:00:00Z","timestamp":1496275200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2017,6,1]],"date-time":"2017-06-01T00:00:00Z","timestamp":1496275200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,2,2]],"date-time":"2023-02-02T00:00:00Z","timestamp":1675296000000},"content-version":"vor","delay-in-days":2072,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Nutrition"],"published-print":{"date-parts":[[2017,6]]},"DOI":"10.3945\/jn.116.244822","type":"journal-article","created":{"date-parts":[[2017,3,16]],"date-time":"2017-03-16T01:00:25Z","timestamp":1489626025000},"page":"1121-1130","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":49,"title":["Pasteurization Procedures for Donor Human Milk Affect Body Growth, Intestinal Structure, and Resistance against Bacterial Infections in Preterm Pigs"],"prefix":"10.1016","volume":"147","author":[{"given":"Yanqi","family":"Li","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Duc Ninh","family":"Nguyen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marita","family":"de Waard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lars","family":"Christensen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ping","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pingping","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anders Miki","family":"Bojesen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charlotte","family":"Lauridsen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jens","family":"Lykkesfeldt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Trine Kastrup","family":"Dalsgaard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stine Brandt","family":"Bering","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Per Torp","family":"Sangild","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.3945\/jn.116.244822_bib1","doi-asserted-by":"crossref","first-page":"2162","DOI":"10.1016\/S0140-6736(12)60820-4","article-title":"National, regional, and worldwide estimates of preterm birth rates in the year 2010 with time trends since 1990 for selected countries: a systematic analysis and implications","volume":"379","author":"Blencowe","year":"2012","journal-title":"Lancet"},{"key":"10.3945\/jn.116.244822_bib2","doi-asserted-by":"crossref","first-page":"F559","DOI":"10.1136\/archdischild-2012-303582","article-title":"Human milk for preterm infants: why, what, when and how?","volume":"98","author":"Menon","year":"2013","journal-title":"Arch Dis Child Fetal Neonatal Ed"},{"key":"10.3945\/jn.116.244822_bib3","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1097\/MPG.0b013e3182a3af0a","article-title":"Donor human milk for preterm infants: current evidence and research directions","volume":"57","author":"Arslanoglu","year":"2013","journal-title":"J Pediatr Gastroenterol Nutr"},{"key":"10.3945\/jn.116.244822_bib4","doi-asserted-by":"crossref","first-page":"1445","DOI":"10.1111\/j.1651-2227.2007.00450.x","article-title":"Pasteurization of mother's own milk reduces fat absorption and growth in preterm infants","volume":"96","author":"Andersson","year":"2007","journal-title":"Acta Paediatr"},{"key":"10.3945\/jn.116.244822_bib5","doi-asserted-by":"crossref","first-page":"1548","DOI":"10.1111\/j.1651-2227.2011.02389.x","article-title":"Improved growth of preterm infants receiving mother's own raw milk compared with pasteurized donor milk","volume":"100","author":"Montjaux-R\u00e9gis","year":"2011","journal-title":"Acta Paediatr"},{"key":"10.3945\/jn.116.244822_bib6","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1159\/000345419","article-title":"Pasteurization of mother's own milk for preterm infants does not reduce the incidence of late-onset sepsis","volume":"103","author":"Cossey","year":"2013","journal-title":"Neonatology"},{"key":"10.3945\/jn.116.244822_bib7","doi-asserted-by":"crossref","first-page":"1131","DOI":"10.3109\/14767058.2015.1038232","article-title":"Improved outcomes of feeding low birth weight infants with predominantly raw human milk versus donor banked milk and formula","volume":"29","author":"Dritsakou","year":"2016","journal-title":"J Matern Fetal Neonatal Med"},{"key":"10.3945\/jn.116.244822_bib8","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1139\/h11-008","article-title":"Effect of pasteurization on immune components of milk: implications for feeding preterm infants","volume":"36","author":"Ewaschuk","year":"2011","journal-title":"Appl Physiol Nutr Metab"},{"key":"10.3945\/jn.116.244822_bib9","doi-asserted-by":"crossref","first-page":"1070","DOI":"10.1111\/j.1651-2227.2008.00870.x","article-title":"Antioxidant capacity of human milk: effect of thermal conditions for the pasteurization","volume":"97","author":"Silvestre","year":"2008","journal-title":"Acta Paediatr"},{"key":"10.3945\/jn.116.244822_bib10","doi-asserted-by":"crossref","first-page":"e85867","DOI":"10.1371\/journal.pone.0085867","article-title":"The effect of UV-C pasteurization on bacteriostatic properties and immunological proteins of donor human milk","volume":"8","author":"Christen","year":"2013","journal-title":"PLoS One"},{"key":"10.3945\/jn.116.244822_bib11","doi-asserted-by":"crossref","first-page":"e68120","DOI":"10.1371\/journal.pone.0068120","article-title":"Ultraviolet-C irradiation: a novel pasteurization method for donor human milk","volume":"8","author":"Christen","year":"2013","journal-title":"PLoS One"},{"key":"10.3945\/jn.116.244822_bib12","doi-asserted-by":"crossref","first-page":"4713","DOI":"10.2527\/jas.2013-6359","article-title":"Invited review: the preterm pig as a model in pediatric gastroenterology","volume":"91","author":"Sangild","year":"2013","journal-title":"J Anim Sci"},{"key":"10.3945\/jn.116.244822_bib13","doi-asserted-by":"crossref","first-page":"R481","DOI":"10.1152\/ajpregu.00349.2015","article-title":"Delayed growth, motor function and learning in preterm pigs during early postnatal life","volume":"310","author":"Andersen","year":"2016","journal-title":"Am J Physiol Regul Integr Comp Physiol"},{"key":"10.3945\/jn.116.244822_bib14","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1177\/1753425915615195","article-title":"Oral antibiotics increase blood neutrophil maturation and reduce bacteremia and necrotizing enterocolitis in the immediate postnatal period of preterm pigs","volume":"22","author":"Nguyen","year":"2016","journal-title":"Innate Immun"},{"key":"10.3945\/jn.116.244822_bib15","doi-asserted-by":"crossref","first-page":"G81","DOI":"10.1152\/ajpgi.00255.2013","article-title":"Raw bovine milk improves gut responses to feeding relative to infant formula in preterm piglets","volume":"306","author":"Li","year":"2014","journal-title":"Am J Physiol Gastrointest Liver Physiol"},{"key":"10.3945\/jn.116.244822_bib16","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1016\/j.jchromb.2008.12.041","article-title":"Plasma citrulline measurement using UPLC tandem mass-spectrometry to determine small intestinal enterocyte pathology","volume":"877","author":"Demacker","year":"2009","journal-title":"J Chromatogr B Analyt Technol Biomed Life Sci"},{"key":"10.3945\/jn.116.244822_bib17","doi-asserted-by":"crossref","first-page":"G310","DOI":"10.1152\/ajpgi.00163.2015","article-title":"Early gradual feeding with bovine colostrum improves gut function and NEC resistance relative to infant formula in preterm pigs","volume":"309","author":"Shen","year":"2015","journal-title":"Am J Physiol Gastrointest Liver Physiol"},{"key":"10.3945\/jn.116.244822_bib18","doi-asserted-by":"crossref","first-page":"1075","DOI":"10.1079\/BJN20061743","article-title":"Formula-feeding reduces lactose digestive capacity in neonatal pigs","volume":"95","author":"Thymann","year":"2006","journal-title":"Br J Nutr"},{"key":"10.3945\/jn.116.244822_bib19","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1159\/000317807","article-title":"Bacterial colonization affects the intestinal proteome of preterm pigs susceptible to necrotizing enterocolitis","volume":"99","author":"Jiang","year":"2011","journal-title":"Neonatology"},{"key":"10.3945\/jn.116.244822_bib20","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1002\/eji.201242462","article-title":"Gut microbiota regulates NKG2D ligand expression on intestinal epithelial cells","volume":"43","author":"Hansen","year":"2013","journal-title":"Eur J Immunol"},{"key":"10.3945\/jn.116.244822_bib21","doi-asserted-by":"crossref","first-page":"e103398","DOI":"10.1371\/journal.pone.0103398","article-title":"A possible link between food and mood: dietary impact on gut microbiota and behavior in BALB\/c mice","volume":"9","author":"Pyndt J\u00f8rgensen","year":"2014","journal-title":"PLoS One"},{"key":"10.3945\/jn.116.244822_bib22","doi-asserted-by":"crossref","first-page":"552","DOI":"10.1177\/0148607114566463","article-title":"Provision of amniotic fluid during parenteral nutrition increases weight gain with limited effects on gut structure, function, immunity, and microbiology in newborn preterm pigs","volume":"40","author":"\u00d8stergaard","year":"2016","journal-title":"JPEN J Parenter Enteral Nutr"},{"key":"10.3945\/jn.116.244822_bib23","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1038\/nmeth.f.303","article-title":"QIIME allows analysis of high-throughput community sequencing data","volume":"7","author":"Caporaso","year":"2010","journal-title":"Nat Methods"},{"key":"10.3945\/jn.116.244822_bib24","doi-asserted-by":"crossref","first-page":"2959","DOI":"10.2527\/jas.2006-744","article-title":"Effect of feeding fermented liquid feed and fermented grain on gastrointestinal ecology and growth performance in piglets","volume":"85","author":"Canibe","year":"2007","journal-title":"J Anim Sci"},{"key":"10.3945\/jn.116.244822_bib25","doi-asserted-by":"crossref","first-page":"1203","DOI":"10.3109\/10715762.2010.499907","article-title":"An inter-laboratory validation of methods of lipid peroxidation measurement in UVA-treated human plasma samples","volume":"44","author":"Breusing","year":"2010","journal-title":"Free Radic Res"},{"key":"10.3945\/jn.116.244822_bib26","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1097\/MPG.0000000000000365","article-title":"rhBSSL improves growth and LCPUFA absorption in preterm infants fed formula or pasteurized breast milk","volume":"59","author":"Casper","year":"2014","journal-title":"J Pediatr Gastroenterol Nutr"},{"key":"10.3945\/jn.116.244822_bib27","doi-asserted-by":"crossref","first-page":"1934","DOI":"10.3945\/jn.113.182931","article-title":"Whey protein processing influences formula-induced gut maturation in preterm pigs","volume":"143","author":"Li","year":"2013","journal-title":"J Nutr"},{"key":"10.3945\/jn.116.244822_bib28","doi-asserted-by":"crossref","first-page":"G480","DOI":"10.1152\/ajpgi.00139.2016","article-title":"Bovine colostrum improves neonatal growth, digestive function and gut immunity relative to donor human milk and infant formula in preterm pigs","volume":"311","author":"Rasmussen","year":"2016","journal-title":"Am J Physiol Gastrointest Liver Physiol"},{"key":"10.3945\/jn.116.244822_bib29","doi-asserted-by":"crossref","first-page":"1796","DOI":"10.1111\/j.1469-0691.2010.03071.x","article-title":"Breast milk causing neonatal sepsis and death","volume":"16","author":"Widger","year":"2010","journal-title":"Clin Microbiol Infect"},{"key":"10.3945\/jn.116.244822_bib30","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/0195-6701(95)90165-5","article-title":"Bacterial contaminated breast milk and necrotizing enterocolitis in preterm twins","volume":"31","author":"Ng","year":"1995","journal-title":"J Hosp Infect"},{"key":"10.3945\/jn.116.244822_bib31","doi-asserted-by":"crossref","first-page":"3390","DOI":"10.1128\/IAI.01698-07","article-title":"Epidermal growth factor inhibits Campylobacter jejuni-induced claudin-4 disruption, loss of epithelial barrier function, and Escherichia coli translocation","volume":"76","author":"Lamb-Rosteski","year":"2008","journal-title":"Infect Immun"},{"key":"10.3945\/jn.116.244822_bib32","doi-asserted-by":"crossref","first-page":"G471","DOI":"10.1152\/ajpgi.00012.2009","article-title":"Enterocyte-specific epidermal growth factor prevents barrier dysfunction and improves mortality in murine peritonitis","volume":"297","author":"Clark","year":"2009","journal-title":"Am J Physiol Gastrointest Liver Physiol"},{"key":"10.3945\/jn.116.244822_bib33","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1016\/0022-3468(95)90566-9","article-title":"The protective role of enteral IgA supplementation in neonatal gut origin sepsis","volume":"30","author":"Maxson","year":"1995","journal-title":"J Pediatr Surg"},{"key":"10.3945\/jn.116.244822_bib34","doi-asserted-by":"crossref","first-page":"512","DOI":"10.1136\/jcp.51.7.512","article-title":"Absence of lysozyme (muramidase) in the intestinal Paneth cells of newborn infants with necrotising enterocolitis","volume":"51","author":"Coutinho","year":"1998","journal-title":"J Clin Pathol"},{"key":"10.3945\/jn.116.244822_bib35","doi-asserted-by":"crossref","first-page":"1235","DOI":"10.1007\/s11248-011-9489-7","article-title":"Lysozyme transgenic goats' milk positively impacts intestinal cytokine expression and morphology","volume":"20","author":"Cooper","year":"2011","journal-title":"Transgenic Res"},{"key":"10.3945\/jn.116.244822_bib36","doi-asserted-by":"crossref","first-page":"1421","DOI":"10.1001\/jama.2009.1403","article-title":"Bovine lactoferrin supplementation for prevention of late-onset sepsis in very low-birth-weight neonates: a randomized trial","volume":"302","author":"Manzoni","year":"2009","journal-title":"JAMA"},{"key":"10.3945\/jn.116.244822_bib37","doi-asserted-by":"crossref","first-page":"G1140","DOI":"10.1152\/ajpgi.2001.281.5.G1140","article-title":"Lactoferrin protects neonatal rats from gut-related systemic infection","volume":"281","author":"Edde","year":"2001","journal-title":"Am J Physiol Gastrointest Liver Physiol"},{"key":"10.3945\/jn.116.244822_bib38","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1023\/B:BIOM.0000027706.51112.62","article-title":"Neonatal small bowel epithelia: enhancing anti-bacterial defense with lactoferrin and Lactobacillus GG","volume":"17","author":"Sherman","year":"2004","journal-title":"Biometals"},{"key":"10.3945\/jn.116.244822_bib39","doi-asserted-by":"crossref","first-page":"486","DOI":"10.1017\/S000711451400107X","article-title":"Enteral supplementation of bovine lactoferrin improves gut barrier function in rats after massive bowel resection","volume":"112","author":"Wu","year":"2014","journal-title":"Br J Nutr"},{"key":"10.3945\/jn.116.244822_bib40","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1038\/jp.2008.203","article-title":"Factors affecting postnatal changes in serum creatinine in preterm infants with gestational age <32 weeks","volume":"29","author":"Iacobelli","year":"2009","journal-title":"J Perinatol"},{"key":"10.3945\/jn.116.244822_bib41","doi-asserted-by":"crossref","first-page":"1217","DOI":"10.1017\/S0007114507868462","article-title":"Addition of oat hulls to an extruded rice-based diet for weaner pigs ameliorates the incidence of diarrhoea and reduces indices of protein fermentation in the gastrointestinal tract","volume":"99","author":"Kim","year":"2008","journal-title":"Br J Nutr"},{"key":"10.3945\/jn.116.244822_bib42","doi-asserted-by":"crossref","first-page":"583","DOI":"10.4161\/gmic.21942","article-title":"Facultative to strict anaerobes ratio in the preterm infant microbiota: a target for intervention?","volume":"3","author":"Arboleya","year":"2012","journal-title":"Gut Microbes"},{"key":"10.3945\/jn.116.244822_bib43","doi-asserted-by":"crossref","first-page":"S41","DOI":"10.1016\/j.earlhumdev.2011.12.027","article-title":"Bacterial colonization and gut development in preterm neonates","volume":"88","author":"Cilieborg","year":"2012","journal-title":"Early Hum Dev"}],"updated-by":[{"DOI":"10.3945\/jn.117.251801","type":"erratum","label":"Erratum","source":"publisher","updated":{"date-parts":[[2017,6,1]],"date-time":"2017-06-01T00:00:00Z","timestamp":1496275200000}}],"container-title":["The Journal of Nutrition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022316622107704?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022316622107704?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.3945\/jn.116.244822","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,12,31]],"date-time":"2024-12-31T16:21:20Z","timestamp":1735662080000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022316622107704"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,6]]},"references-count":43,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2017,6]]}},"alternative-id":["S0022316622107704"],"URL":"https:\/\/doi.org\/10.3945\/jn.116.244822","relation":{"erratum":[{"id-type":"doi","id":"10.3945\/jn.117.251801","asserted-by":"object"}]},"ISSN":["0022-3166"],"issn-type":[{"value":"0022-3166","type":"print"}],"subject":[],"published":{"date-parts":[[2017,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Pasteurization Procedures for Donor Human Milk Affect Body Growth, Intestinal Structure, and Resistance against Bacterial Infections in Preterm Pigs","name":"articletitle","label":"Article Title"},{"value":"The Journal of Nutrition","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.3945\/jn.116.244822","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2017 American Society for Nutrition. Published by Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}