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Front Oncol. 2023; 13: 1078029.","DOI":"10.3389\/fonc.2023.1078029"},{"key":"2","doi-asserted-by":"crossref","unstructured":"2 Kawamura                            I,                                Ohe                            R,                                Suzuki                            K                    <i>et al.<\/i> Neighboring macrophage-induced alteration in the                    phenotype of colorectal cancer cells in the tumor budding area. Cancer Cell Int.                    2024; 24: 107.","DOI":"10.1186\/s12935-024-03292-7"},{"key":"3","doi-asserted-by":"crossref","unstructured":"3 Casari                            M,                                Siegl                            D,                                Deppermann                            C,                                Schuppan                            D. Macrophages                    and platelets in liver fibrosis and hepatocellular carcinoma. Front Immunol.                    2023; 14: 1277808.","DOI":"10.3389\/fimmu.2023.1277808"},{"key":"4","doi-asserted-by":"crossref","unstructured":"4 Chang                            CY,                                Armstrong                            D,                                Corry                            DB,                                Kheradmand                            F. Alveolar                    macrophages in lung cancer: opportunities challenges. Front Immunol. 2023; 14:                        1268939.","DOI":"10.3389\/fimmu.2023.1268939"},{"key":"5","doi-asserted-by":"crossref","unstructured":"5 Yin                            Y,                                Yao                            S,                                Hu                            Y                    <i>et al.<\/i> The Immune-microenvironment confers chemoresistance of                    colorectal cancer through macrophage-derived IL6. Clin Cancer Res. 2017; 23:                    7375-7387.","DOI":"10.1158\/1078-0432.CCR-17-1283"},{"key":"6","doi-asserted-by":"crossref","unstructured":"6 Tu                            W,                                Gong                            J,                                Zhou                            Z,                                Tian                            D,                                Wang                            Z. TCF4 enhances                    hepatic metastasis of colorectal cancer by regulating tumor-associated                    macrophage via CCL2\/CCR2 signaling. Cell Death Dis. 2021; 12:                    882.","DOI":"10.1038\/s41419-021-04166-w"},{"key":"7","doi-asserted-by":"crossref","unstructured":"7 Komohara                            Y,                                Kurotaki                            D,                                Tsukamoto                            H                    <i>et al.<\/i> Involvement of protumor macrophages in breast cancer                    progression and characterization of macrophage phenotypes. Cancer Sci. 2023;                    114: 2220-2229.","DOI":"10.1111\/cas.15751"},{"key":"8","doi-asserted-by":"crossref","unstructured":"8 Takeya                            M,                                Komohara                            Y. Role of                    tumor-associated macrophages in human malignancies: friend or foe? Pathol Int.                    2016; 66: 491-505.","DOI":"10.1111\/pin.12440"},{"key":"9","doi-asserted-by":"crossref","unstructured":"9 Komohara                            Y,                                Horlad                            H,                                Ohnishi                            K                    <i>et al.<\/i> M2 macrophage\/microglial cells induce activation of                    Stat3 in primary central nervous system lymphoma. J Clin Exp Hematop. 2011; 51:                    93-99.","DOI":"10.3960\/jslrt.51.93"},{"key":"10","doi-asserted-by":"crossref","unstructured":"10 Shiraishi                            D,                                Fujiwara                            Y,                                Horlad                            H                    <i>et al.<\/i> CD163 is required for protumoral activation of                    macrophages in human and murine sarcoma. Cancer Res. 2018; 78:                    3255-3266.","DOI":"10.1158\/0008-5472.CAN-17-2011"},{"key":"11","doi-asserted-by":"crossref","unstructured":"11 Komohara                            Y,                                Takemura                            K,                                Lei                            XF                    <i>et al.<\/i> Delayed growth of EL4 lymphoma in SR-A-deficient mice is                    due to upregulation of nitric oxide and interferon-gamma production by                    tumor-associated macrophages. Cancer Sci. 2009; 100: 2160-2166.","DOI":"10.1111\/j.1349-7006.2009.01296.x"},{"key":"12","doi-asserted-by":"crossref","unstructured":"12 Kelley                            T,                                Beck                            R,                                Absi                            A                    <i>et al.<\/i> Biologic predictors in follicular lymphoma: importance                    of markers of immune response. Leuk Lymphoma. 2007; 48:                    2403-2411.","DOI":"10.1080\/10428190701665954"},{"key":"13","doi-asserted-by":"crossref","unstructured":"13 Kridel                            R,                                Xerri                            L,                                Gelas-Dore                            B                    <i>et al.<\/i> The prognostic impact of CD163-positive macrophages in                    follicular lymphoma: a study from the BC Cancer Agency and the Lymphoma Study                    Association. Clin Cancer Res. 2015; 21: 3428-3435.","DOI":"10.1158\/1078-0432.CCR-14-3253"},{"key":"14","doi-asserted-by":"crossref","unstructured":"14 Yoon                            DH,                                Koh                            YW,                                Kang                            HJ                    <i>et al.<\/i> CD68 and CD163 as prognostic factors for Korean patients                    with Hodgkin lymphoma. Eur J Haematol. 2012; 88: 292-305.","DOI":"10.1111\/j.1600-0609.2011.01731.x"},{"key":"15","doi-asserted-by":"crossref","unstructured":"15 Karihtala                            K,                                Leivonen                            SK,                                Br\u00fcck                            O                    <i>et al.<\/i> Prognostic impact of tumor-associated macrophages on                    survival is checkpoint dependent in classical Hodgkin lymphoma. Cancers (Basel).                    2020; 12: 877.","DOI":"10.3390\/cancers12040877"},{"key":"16","doi-asserted-by":"crossref","unstructured":"16 Niino                            D,                                Komohara                            Y,                                Murayama                            T                    <i>et al.<\/i> Ratio of M2 macrophage expression is closely associated                    with poor prognosis for Angioimmunoblastic T-cell lymphoma (AITL). Pathol Int.                    2010; 60: 278-283.","DOI":"10.1111\/j.1440-1827.2010.02514.x"},{"key":"17","doi-asserted-by":"crossref","unstructured":"17 Marchesi                            F,                                Cirillo                            M,                                Bianchi                            A                    <i>et al.<\/i> High density of CD68+\/CD163+ tumour-associated                    macrophages (M2-TAM) at diagnosis is significantly correlated to unfavorable                    prognostic factors and to poor clinical outcomes in patients with diffuse large                    B-cell lymphoma. Hematol Oncol. 2015; 33: 110-112.","DOI":"10.1002\/hon.2142"},{"key":"18","doi-asserted-by":"crossref","unstructured":"18 Lin                            M,                                Ma                            S,                                Sun                            L,                                Qin                            Z. The                    prognostic value of tumor-associated macrophages detected by immunostaining in                    diffuse large B cell lymphoma: A meta-analysis. Front Oncol. 2023; 12:                        1094400.","DOI":"10.3389\/fonc.2022.1094400"},{"key":"19","doi-asserted-by":"crossref","unstructured":"19 Suzuki                            K,                                Ohe                            R,                                Kabasawa                            T                    <i>et al.<\/i> Histological spatial analysis on the induction of PD-L1+                    macrophages by CD8+ T cells at the marginal microenvironment of triple-negative                    breast cancer. Breast Cancer. 2023; 30: 1094-1104.","DOI":"10.1007\/s12282-023-01507-9"},{"key":"20","doi-asserted-by":"crossref","unstructured":"20 Cencini                            E,                                Fabbri                            A,                                Sicuranza                            A,                                Gozzetti                            A,                                Bocchia                            M. The role of                    tumor-associated macrophages in hematologic malignancies. Cancers (Basel). 2021;                    13: 3597.","DOI":"10.3390\/cancers13143597"},{"key":"21","doi-asserted-by":"crossref","unstructured":"21 Akter                            R,                                Kim                            K,                                Kwon                            HY                    <i>et al.<\/i> EMR1\/ADGRE1 expression in cancer cells upregulated by                    tumor-associated macrophages is related to poor prognosis in colorectal cancer.                    Biomedicines. 2022; 10: 3121.","DOI":"10.3390\/biomedicines10123121"},{"key":"22","doi-asserted-by":"crossref","unstructured":"22 Mao                            H,                                Pan                            F,                                Guo                            H                    <i>et al.<\/i> Feedback mechanisms between M2 macrophages and Th17                    cells in colorectal cancer patients. Tumour Biol. 2016; 37:                    12223-12230.","DOI":"10.1007\/s13277-016-5085-z"},{"key":"23","doi-asserted-by":"crossref","unstructured":"23 Xie                            Y,                                Yang                            H,                                Yang                            C                    <i>et al.<\/i> Role and mechanisms of tumor-associated macrophages in                    hematological malignancies. Front Oncol. 2022; 12:                        933666.","DOI":"10.3389\/fonc.2022.933666"},{"key":"24","doi-asserted-by":"crossref","unstructured":"24 Blanco                            M,                                Collazo-Lorduy                            A,                                Yanguas-Cas\u00e1s                            N,                                Calvo                            V,                                Provencio                            M. Unveiling the                    role of the tumor microenvironment in the treatment of follicular lymphoma.                    Cancers (Basel). 2022; 14: 2158.","DOI":"10.3390\/cancers14092158"},{"key":"25","doi-asserted-by":"crossref","unstructured":"25 Li                            L,                                Zhang                            J,                                Chen                            J                    <i>et al.<\/i> B-cell receptor-mediated NFATc1 activation induces                    IL-10\/STAT3\/PD-L1 signaling in diffuse large B-cell lymphoma. Blood. 2018; 132:                    1805-1817.","DOI":"10.1182\/blood-2018-03-841015"},{"key":"26","doi-asserted-by":"crossref","unstructured":"26 Epron                            G,                                Ame-Thomas                            P, Le                                Priol                            J                    <i>et al.<\/i> Monocytes and T cells cooperate to favor normal and                    follicular lymphoma B-cell growth: role of IL-15 and CD40L signaling. Leukemia.                    2012; 26: 139-148.","DOI":"10.1038\/leu.2011.179"},{"key":"27","doi-asserted-by":"crossref","unstructured":"27 Holtick                            U,                                Vockerodt                            M,                                Pinkert                            D                    <i>et al.<\/i> STAT3 is essential for Hodgkin lymphoma cell                    proliferation and is a target of tyrphostin AG17 which confers sensitization for                    apoptosis. Leukemia. 2005; 19: 936-944.","DOI":"10.1038\/sj.leu.2403750"},{"key":"28","doi-asserted-by":"crossref","unstructured":"28 Gupta                            M,                                Han                            JJ,                                Stenson                            M                    <i>et al.<\/i> Elevated serum IL-10 levels in diffuse large B-cell                    lymphoma: a mechanism of aberrant JAK2 activation. Blood. 2012; 119:                    2844-2853.","DOI":"10.1182\/blood-2011-10-388538"},{"key":"29","doi-asserted-by":"crossref","unstructured":"29 Tamma                            R,                                Ranieri                            G,                                Ingravallo                            G                    <i>et al.<\/i> Inflammatory cells in diffuse large B cell lymphoma. J                    Clin Med. 2020; 9: 2418.","DOI":"10.3390\/jcm9082418"},{"key":"30","doi-asserted-by":"crossref","unstructured":"30 Tamma                            R,                                Ingravallo                            G,                                Gaudio                            F                    <i>et al.<\/i> STAT3, tumor microenvironment, and microvessel density                    in diffuse large B cell lymphomas. Leuk Lymphoma. 2020; 61:                    567-574.","DOI":"10.1080\/10428194.2019.1678154"},{"key":"31","doi-asserted-by":"crossref","unstructured":"31 Ohe                            R,                                Aung                            NY,                                Meng                            H                    <i>et al.<\/i> Localization of collagen modifying enzymes on                    fibroblastic reticular cells and follicular dendritic cells in non-neoplastic                    and neoplastic lymphoid tissues. Leuk Lymphoma. 2016; 57:                    1687-1696.","DOI":"10.3109\/10428194.2015.1107907"},{"key":"32","doi-asserted-by":"crossref","unstructured":"32 Watanabe                            T. The tumor                    microenvironment in follicular lymphoma: Its pro-malignancy role with                    therapeutic potential. Int J Mol Sci. 2021; 22: 5352.","DOI":"10.3390\/ijms22105352"},{"key":"33","doi-asserted-by":"crossref","unstructured":"33 Abe                            Y,                                Sakata-Yanagimoto                            M,                                Fujisawa                            M                    <i>et al.<\/i> A single-cell atlas of non-haematopoietic cells in human                    lymph nodes and lymphoma reveals a landscape of stromal remodelling. Nat Cell                    Biol. 2022; 24: 565-578.","DOI":"10.1038\/s41556-022-00866-3"},{"key":"34","doi-asserted-by":"crossref","unstructured":"34 Staiger                            AM,                                Duppel                            J,                                Dengler                            MA                    <i>et al.<\/i> An analysis of the role of follicular                    lymphoma-associated fibroblasts to promote tumor cell viability following                    drug-induced apoptosis. Leuk Lymphoma. 2017; 58: 1922-1930.","DOI":"10.1080\/10428194.2016.1263841"},{"key":"35","doi-asserted-by":"crossref","unstructured":"35 Celegato                            M,                                Borghese                            C,                                Casagrande                            N                    <i>et al.<\/i> Bortezomib down-modulates the survival factor interferon                    regulatory factor 4 in Hodgkin lymphoma cell lines and decreases the protective                    activity of Hodgkin lymphoma-associated fibroblasts. Leuk Lymphoma. 2014; 55:                    149-159.","DOI":"10.3109\/10428194.2013.800196"},{"key":"36","doi-asserted-by":"crossref","unstructured":"36 Thomazy                            VA,                                Vega                            F,                                Medeiros                            LJ,                                Davies                            PJ,                                Jones                            D. Phenotypic                    modulation of the stromal reticular network in normal and neoplastic lymph                    nodes: tissue transglutaminase reveals coordinate regulation of multiple cell                    types. Am J Pathol. 2003; 163: 165-174.","DOI":"10.1016\/S0002-9440(10)63640-1"},{"key":"37","doi-asserted-by":"crossref","unstructured":"37 Mourcin                            F,                                Verdi\u00e8re                            L,                                Roulois                            D                    <i>et al.<\/i> Follicular lymphoma triggers phenotypic and functional                    remodeling of the human lymphoid stromal cell landscape. Immunity. 2021; 54:                    1788-1806.e7.","DOI":"10.1016\/j.immuni.2021.05.019"},{"key":"38","doi-asserted-by":"crossref","unstructured":"38 Apollonio                            B,                                Spada                            F,                                Petrov                            N                    <i>et al.<\/i> Tumor-activated lymph node fibroblasts suppress T cell                    function in diffuse large B cell lymphoma. J Clin Invest. 2023; 133:                        e166070.","DOI":"10.1172\/JCI166070"},{"key":"39","doi-asserted-by":"crossref","unstructured":"39 Salem                            A,                                Alotaibi                            M,                                Mroueh                            R,                                Basheer                            HA,                                Afarinkia                            K. CCR7 as a                    therapeutic target in Cancer. Biochim Biophys Acta Rev Cancer. 2021; 1875:                        188499.","DOI":"10.1016\/j.bbcan.2020.188499"},{"key":"40","doi-asserted-by":"crossref","unstructured":"40 Gon\u00e7alves                            TL, de                                Ara\u00fajo                            LP,                                Pereira Ferrer                            V. Tamoxifen as                    a modulator of CXCL12-CXCR4-CXCR7 chemokine axis: A breast cancer and                    glioblastoma view. Cytokine. 2023; 170:                    156344.","DOI":"10.1016\/j.cyto.2023.156344"},{"key":"41","doi-asserted-by":"crossref","unstructured":"41 Hussain                            M,                                Adah                            D,                                Tariq                            M                    <i>et al.<\/i> CXCL13\/CXCR5 signaling axis in cancer. Life Sci. 2019;                    227: 175-186.","DOI":"10.1016\/j.lfs.2019.04.053"},{"key":"42","doi-asserted-by":"crossref","unstructured":"42 Wang                            B,                                Wang                            M,                                Ao                            D,                                Wei                            X. CXCL13-CXCR5                    axis: Regulation in inflammatory diseases and cancer. Biochim Biophys Acta Rev                    Cancer. 2022; 1877: 188799.","DOI":"10.1016\/j.bbcan.2022.188799"},{"key":"43","doi-asserted-by":"crossref","unstructured":"43 Marques-Piubelli                            ML,                                Amador                            C,                                Vega                            F. Pathologic                    and molecular insights in nodal T-follicular helper cell lymphomas. Front Oncol.                    2023; 13: 1105651.","DOI":"10.3389\/fonc.2023.1105651"},{"key":"44","doi-asserted-by":"crossref","unstructured":"44 Qian                            BZ,                                Li                            J,                                Zhang                            H                    <i>et al.<\/i> CCL2 recruits inflammatory monocytes to facilitate                    breast-tumour metastasis. Nature. 2011; 475: 222-225.","DOI":"10.1038\/nature10138"},{"key":"45","doi-asserted-by":"crossref","unstructured":"45 Guilloton                            F,                                Caron                            G,                                M\u00e9nard                            C                    <i>et al.<\/i> Mesenchymal stromal cells orchestrate follicular                    lymphoma cell niche through the CCL2-dependent recruitment and polarization of                    monocytes. Blood. 2012; 119: 2556-2567.","DOI":"10.1182\/blood-2011-08-370908"},{"key":"46","doi-asserted-by":"crossref","unstructured":"46 Husson                            H,                                Carideo                            EG,                                Cardoso                            AA                    <i>et al.<\/i> MCP-1 modulates chemotaxis by follicular lymphoma cells.                    Br J Haematol. 2001; 115: 554-562.","DOI":"10.1046\/j.1365-2141.2001.03145.x"},{"key":"47","doi-asserted-by":"crossref","unstructured":"47 Fu                            L,                                Lin-Lee                            YC,                                Pham                            LV                    <i>et al.<\/i> BAFF-R promotes cell proliferation and survival through                    interaction with IKKbeta and NF-kappaB\/c-Rel in the nucleus of normal and                    neoplastic B-lymphoid cells. Blood. 2009; 113: 4627-4636.","DOI":"10.1182\/blood-2008-10-183467"},{"key":"48","doi-asserted-by":"crossref","unstructured":"48 Dubey                            LK,                                Karempudi                            P,                                Luther                            SA,                                Ludewig                            B,                                Harris                            NL. Interactions                    between fibroblastic reticular cells and B cells promote mesenteric lymph node                    lymphangiogenesis. Nat Commun. 2017; 8: 367.","DOI":"10.1038\/s41467-017-00504-9"},{"key":"49","doi-asserted-by":"crossref","unstructured":"49 Li                            YJ,                                Jiang                            WQ,                                Rao                            HL                    <i>et al.<\/i> Expression of BAFF and BAFF-R in follicular lymphoma:                    correlation with clinicopathologic characteristics and survival outcomes. PLoS                    One. 2012; 7: e50936.","DOI":"10.1371\/journal.pone.0050936"},{"key":"50","doi-asserted-by":"crossref","unstructured":"50 Ohshima                            K,                                Akaiwa                            M,                                Umeshita                            R                    <i>et al.<\/i> Interleukin-13 and interleukin-13 receptor in Hodgkin\u2019s                    disease: possible autocrine mechanism and involvement in fibrosis.                    Histopathology. 2001; 38: 368-375.","DOI":"10.1046\/j.1365-2559.2001.01083.x"},{"key":"51","doi-asserted-by":"crossref","unstructured":"51 Hold                            GL,                                Untiveros                            P,                                Saunders                            KA,                                El-Omar                            EM. Role of host                    genetics in fibrosis. Fibrogenesis Tissue Repair. 2009; 2: 6.","DOI":"10.1186\/1755-1536-2-6"},{"key":"52","doi-asserted-by":"crossref","unstructured":"52 Nahm                            JH,                                Yang                            WI,                                Yoon                            SO. Forkhead box                    C1 (FOXC1) expression in stromal cells within the microenvironment of T and NK                    Cell lymphomas: Association with tumor dormancy and activation. Cancer Res                    Treat. 2020; 52: 1273-1282.","DOI":"10.4143\/crt.2020.032"},{"key":"53","doi-asserted-by":"crossref","unstructured":"53 Dubey                            LK,                                Ludewig                            B,                                Luther                            SA,                                Harris                            NL.                    IL-4R\u03b1-expressing B cells are required for CXCL13 production by fibroblastic                    reticular cells. Cell Rep. 2019; 27: 2442-2458.e5.","DOI":"10.1016\/j.celrep.2019.04.079"},{"key":"54","doi-asserted-by":"crossref","unstructured":"54 Ohtani                            H,                                Komeno                            T,                                Agatsuma                            Y                    <i>et al.<\/i> Follicular dendritic cell meshwork in angioimmunoblastic                    T-cell lymphoma is characterized by accumulation of CXCL13(+) cells. J Clin Exp                    Hematop. 2015; 55: 61-69.","DOI":"10.3960\/jslrt.55.61"},{"key":"55","doi-asserted-by":"crossref","unstructured":"55 Uhl                            B,                                Prochazka                            KT,                                Pansy                            K                    <i>et al.<\/i> Distinct chemokine receptor expression profiles in de                    novo DLBCL, transformed follicular lymphoma, Richter\u2019s transformed DLBCL and                    germinal center B-cells. Int J Mol Sci. 2022; 23: 7874.","DOI":"10.3390\/ijms23147874"},{"key":"56","doi-asserted-by":"crossref","unstructured":"56 Wada                            K,                                Maeda                            K,                                Tajima                            K                    <i>et al.<\/i> Expression of BAFF-R and TACI in reactive lymphoid                    tissues and B-cell lymphomas. Histopathology. 2009; 54:                    221-232.","DOI":"10.1111\/j.1365-2559.2008.03203.x"},{"key":"57","doi-asserted-by":"crossref","unstructured":"57 Takahata                            H,                                Ohara                            N,                                Ichimura                            K                    <i>et al.<\/i> BAFF-R is expressed on B-cell lymphomas depending on                    their origin, and is related to proliferation index of nodal diffuse large                    B-cell lymphomas. J Clin Exp Hematop. 2010; 50: 121-127.","DOI":"10.3960\/jslrt.50.121"},{"key":"58","doi-asserted-by":"crossref","unstructured":"58 Katakai                            T,                                Hara                            T,                                Sugai                            M,                                Gonda                            H,                                Shimizu                            A. Lymph node                    fibroblastic reticular cells construct the stromal reticulum via contact with                    lymphocytes. J Exp Med. 2004; 200: 783-795.","DOI":"10.1084\/jem.20040254"},{"key":"59","doi-asserted-by":"crossref","unstructured":"59 Sugimoto                            K,                                Hayakawa                            F,                                Shimada                            S                    <i>et al.<\/i> Discovery of a drug targeting microenvironmental support                    for lymphoma cells by screening using patient-derived xenograft cells. Sci Rep.                    2015; 5: 13054.","DOI":"10.1038\/srep13054"},{"key":"60","doi-asserted-by":"crossref","unstructured":"60 Ohe                            R,                                Yang                            S,                                Yamashita                            D                    <i>et al.<\/i> Pathogenesis of follicular thymic hyperplasia associated                    with rheumatoid arthritis. Pathol Int. 2022; 72: 252-260.","DOI":"10.1111\/pin.13212"},{"key":"61","doi-asserted-by":"crossref","unstructured":"61 Carbone                            A,                                Gloghini                            A,                                Cabras                            A,                                Elia                            G. The Germinal                    centre-derived lymphomas seen through their cellular microenvironment. Br J                    Haematol. 2009; 145: 468-480.","DOI":"10.1111\/j.1365-2141.2009.07651.x"},{"key":"62","doi-asserted-by":"crossref","unstructured":"62 Cui                            W,                                Che                            L,                                Sato                            Y                    <i>et al.<\/i> Nodal follicular lymphoma without complete follicular                    dendritic cell networks is related to localized clinical stage. Pathol Int.                    2011; 61: 737-741.","DOI":"10.1111\/j.1440-1827.2011.02736.x"},{"key":"63","doi-asserted-by":"crossref","unstructured":"63 Ohe                            R,                                Meng                            HX,                                Yamada                            A                    <i>et al.<\/i> Good prognosis for follicular lymphoma with estrogen                    receptor \u03b1-positive follicular dendritic cells. Hematol Oncol. 2020; 38:                    293-300.","DOI":"10.1002\/hon.2730"},{"key":"64","doi-asserted-by":"crossref","unstructured":"64 Blaker                            YN,                                Spetalen                            S,                                Brodtkorb                            M                    <i>et al.<\/i> The tumour microenvironment influences survival and time                    to transformation in follicular lymphoma in the rituximab era. Br J Haematol.                    2016; 175: 102-114.","DOI":"10.1111\/bjh.14201"},{"key":"65","doi-asserted-by":"crossref","unstructured":"65 Blonska                            M,                                Agarwal                            NK,                                Vega                            F. Shaping of                    the tumor microenvironment: Stromal cells and vessels. Semin Cancer Biol. 2015;                    34: 3-13.","DOI":"10.1016\/j.semcancer.2015.03.002"},{"key":"66","doi-asserted-by":"crossref","unstructured":"66 Fan                            Z,                                Natkunam                            Y,                                Bair                            E,                                Tibshirani                            R,                                Warnke                            RA.                    Characterization of variant patterns of nodular lymphocyte predominant hodgkin                    lymphoma with immunohistologic and clinical correlation. Am J Surg Pathol. 2003;                    27: 1346-1356.","DOI":"10.1097\/00000478-200310000-00007"},{"key":"67","doi-asserted-by":"crossref","unstructured":"67 Kojima                            M,                                Nakamura                            S,                                Itoh                            H                    <i>et al.<\/i> Angioimmunoblastic T-cell lymphoma with hyperplastic                    germinal centers: a clinicopathological and immunohistochemical study of 10                    cases. APMIS. 2001; 109: 699-706.","DOI":"10.1034\/j.1600-0463.2001.d01-135.x"},{"key":"68","unstructured":"68 Quintanilla-Martinez L, Ott G.                    Angioimmunoblastic T-cell lymphoma. In: Jaffe ES, Arber DA, Campo E, Harris NL,                    Quintanilla-Martinez L (eds): Hematopathology. 2nd ed, Amsterdam, ELSEVIER.                    2017; pp. 659-672."},{"key":"69","doi-asserted-by":"crossref","unstructured":"69 Lee                            CG,                                Das                            B,                                Lin                            TL                    <i>et al.<\/i> A rare fraction of drug-resistant follicular lymphoma                    cancer stem cells interacts with follicular dendritic cells to maintain                    tumourigenic potential. Br J Haematol. 2012; 158: 79-90.","DOI":"10.1111\/j.1365-2141.2012.09123.x"},{"key":"70","doi-asserted-by":"crossref","unstructured":"70 Shi                            Y,                                Riese                            DJ                            2nd, Shen                            J. The role of                    the CXCL12\/CXCR4\/CXCR7 chemokine axis in cancer. Front Pharmacol. 2020; 11:                        574667.","DOI":"10.3389\/fphar.2020.574667"},{"key":"71","doi-asserted-by":"crossref","unstructured":"71 Ohe                            R,                                Meng                            HX, Ye                                Aung                            N                    <i>et al.<\/i> Differential expression of estrogen receptor-\u03b1 on                    follicular dendritic cells from patients with grade 1-2 and grade 3 follicular                    lymphoma. Hematol Oncol. 2019; 37: 151-159.","DOI":"10.1002\/hon.2577"},{"key":"72","doi-asserted-by":"crossref","unstructured":"72 Valero                            JG,                                Matas-C\u00e9spedes                            A,                                Arenas                            F                    <i>et al.<\/i> The receptor of the colony-stimulating factor-1 (CSF-1R)                    is a novel prognostic factor and therapeutic target in follicular lymphoma.                    Leukemia. 2021; 35: 2635-2649.","DOI":"10.1038\/s41375-021-01201-9"},{"key":"73","doi-asserted-by":"crossref","unstructured":"73 Fei                            L,                                Ren                            X,                                Yu                            H,                                Zhan                            Y. Targeting the                    CCL2\/CCR2 axis in cancer immunotherapy: one stone, three birds? Front Immunol.                    2021; 12: 771210.","DOI":"10.3389\/fimmu.2021.771210"},{"key":"74","doi-asserted-by":"crossref","unstructured":"74 Meng                            H,                                Li                            H,                                Ohe                            R                    <i>et al.<\/i> Thymic stromal lymphopoietin in tonsillar follicular                    dendritic cells correlates with elevated serum immunoglobulin A titer by                    promoting tonsillar immunoglobulin A class switching in immunoglobulin A                    nephropathy. Transl Res. 2016; 176: 1-17.","DOI":"10.1016\/j.trsl.2016.04.008"},{"key":"75","doi-asserted-by":"crossref","unstructured":"75 Aldinucci                            D,                                Gloghini                            A,                                Pinto                            A, De                                Filippi                            R,                                Carbone                            A. The classical                    Hodgkin\u2019s lymphoma microenvironment and its role in promoting tumour growth and                    immune escape. J Pathol. 2010; 221: 248-263.","DOI":"10.1002\/path.2711"},{"key":"76","doi-asserted-by":"crossref","unstructured":"76 Mungu\u00eda-Fuentes                            R,                                Maqueda-Alfaro                            RA,                                Chac\u00f3n-Salinas                            R,                                Flores-Romo                            L,                                Yam-Puc                            JC. Germinal                    center cells turning to the dark side: Neoplasms of B cells, follicular helper T                    cells, and follicular dendritic cells. Front Oncol. 2021; 10:                        587809.","DOI":"10.3389\/fonc.2020.587809"},{"key":"77","doi-asserted-by":"crossref","unstructured":"77 Francis                            K,                                Palsson                            BO. Effective                    intercellular communication distances are determined by the relative time                    constants for cyto\/chemokine secretion and diffusion. Proc Natl Acad Sci USA.                    1997; 94: 12258-12262.","DOI":"10.1073\/pnas.94.23.12258"},{"key":"78","doi-asserted-by":"crossref","unstructured":"78 Carey                            CD,                                Gusenleitner                            D,                                Lipschitz                            M                    <i>et al.<\/i> Topological analysis reveals a PD-L1-associated                    microenvironmental niche for Reed-Sternberg cells in Hodgkin lymphoma. Blood.                    2017; 130: 2420-2430.","DOI":"10.1182\/blood-2017-03-770719"},{"key":"79","doi-asserted-by":"crossref","unstructured":"79 Aoki                            T,                                Steidl                            C. Novel                    insights into Hodgkin lymphoma biology by\u00a0single-cell analysis. Blood. 2023;                    141: 1791-1801.","DOI":"10.1182\/blood.2022017147"},{"key":"80","doi-asserted-by":"crossref","unstructured":"80 Haebe                            S,                                Shree                            T,                                Sathe                            A                    <i>et al.<\/i> Single-cell analysis can define distinct evolution of                    tumor sites in follicular lymphoma. Blood. 2021; 137:                    2869-2880.","DOI":"10.1182\/blood.2020009855"}],"container-title":["Journal of Clinical and Experimental Hematopathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/jslrt\/64\/3\/64_24034\/_pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,9,28]],"date-time":"2024-09-28T01:07:08Z","timestamp":1727485628000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/jslrt\/64\/3\/64_24034\/_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024]]},"references-count":80,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2024]]}},"URL":"https:\/\/doi.org\/10.3960\/jslrt.24034","relation":{},"ISSN":["1346-4280","1880-9952"],"issn-type":[{"value":"1346-4280","type":"print"},{"value":"1880-9952","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024]]},"article-number":"24034"}}