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Blood. 2017; 130:                    1800-1808.","DOI":"10.1182\/blood-2017-03-769620"},{"key":"2","doi-asserted-by":"crossref","unstructured":"2 Thieblemont                            C,                                Phillips                            T,                                Ghesquieres                            H                    <i>et al.<\/i> Epcoritamab, a novel, subcutaneous CD3xCD20 bispecific                    T-cell-engaging antibody, in relapsed or refractory large B-cell lymphoma: dose                    expansion in a phase I\/II trial. J Clin Oncol. 2023; 41:                    2238-2247.","DOI":"10.1200\/JCO.22.01725"},{"key":"3","doi-asserted-by":"crossref","unstructured":"3 Thieblemont                            C,                                Karimi                            YH,                                Ghesquieres                            H                    <i>et al.<\/i> Epcoritamab in relapsed\/refractory large B-cell                    lymphoma: 2-year follow-up from the pivotal EPCORE NHL-1 trial. Leukemia. 2024;                    38: 2653-2662.","DOI":"10.1038\/s41375-024-02410-8"},{"key":"4","doi-asserted-by":"crossref","unstructured":"4 Dickinson                            MJ,                                Carlo-Stella                            C,                                Morschhauser                            F                    <i>et al.<\/i> Glofitamab for relapsed or refractory diffuse large                    B-cell lymphoma. N Engl J Med. 2022; 387: 2220-2231.","DOI":"10.1056\/NEJMoa2206913"},{"key":"5","doi-asserted-by":"crossref","unstructured":"5 Bartlett                            NL,                                Assouline                            S,                                Giri                            P                    <i>et al.<\/i> Mosunetuzumab monotherapy is active and tolerable in                    patients with relapsed\/refractory diffuse large B-cell lymphoma. Blood Adv.                    2023; 7: 4926-4935.","DOI":"10.1182\/bloodadvances.2022009260"},{"key":"6","doi-asserted-by":"crossref","unstructured":"6 Bannerji                            R,                                Arnason                            JE,                                Advani                            RH                    <i>et al.<\/i> Odronextamab, a human CD20\u00d7CD3 bispecific antibody in                    patients with CD20-positive B-cell malignancies (ELM-1): results from the                    relapsed or refractory non-Hodgkin lymphoma cohort in a single-arm, multicentre,                    phase 1 trial. 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Blood.                    2019; 133: 2401-2412.","DOI":"10.1182\/blood.2018889931"},{"key":"10","doi-asserted-by":"crossref","unstructured":"10 Bargou                            R,                                Leo                            E,                                Zugmaier                            G                    <i>et al.<\/i> Tumor regression in cancer patients by very low doses of                    a T cell-engaging antibody. Science. 2008; 321: 974-977.","DOI":"10.1126\/science.1158545"},{"key":"11","doi-asserted-by":"crossref","unstructured":"11 Sun                            LL,                                Ellerman                            D,                                Mathieu                            M                    <i>et al.<\/i> Anti-CD20\/CD3 T cell-dependent bispecific antibody for                    the treatment of B cell malignancies. Sci Transl Med. 2015; 7:                        287ra70.","DOI":"10.1126\/scitranslmed.aaa4802"},{"key":"12","doi-asserted-by":"crossref","unstructured":"12 Engelberts                            PJ,                                Hiemstra                            IH, de                                Jong                            B                    <i>et al.<\/i> DuoBody-CD3xCD20 induces potent T-cell-mediated killing                    of malignant B cells in preclinical models and provides opportunities for                    subcutaneous dosing. EBioMedicine. 2020; 52:                    102625.","DOI":"10.1016\/j.ebiom.2019.102625"},{"key":"13","doi-asserted-by":"crossref","unstructured":"13 Bacac                            M,                                Colombetti                            S,                                Herter                            S                    <i>et al.<\/i> CD20-TCB with obinutuzumab pretreatment as                    next-generation treatment of hematologic malignancies. Clin Cancer Res. 2018;                    24: 4785-4797.","DOI":"10.1158\/1078-0432.CCR-18-0455"},{"key":"14","doi-asserted-by":"crossref","unstructured":"14 Rosenthal                            A,                                Munoz                            J,                                Jun                            M                    <i>et al.<\/i> Comparisons of treatment outcomes of epcoritamab versus                    chemoimmunotherapy, polatuzumab-based regimens, tafasitamab-based regimens, or                    chimeric antigen receptor T-cell therapy, in third-line or later                    relapsed\/refractory large B-cell lymphoma. J Hematol Oncol. 2024; 17:                    69.","DOI":"10.1186\/s13045-024-01594-x"},{"key":"15","doi-asserted-by":"crossref","unstructured":"15 Shumilov                            E,                                Wurm-Kuczera                            R,                                Kerkhoff                            A                    <i>et al.<\/i> Safety and efficacy of glofitamab for                    relapsed\/refractory large B-cell lymphoma in a multinational real-world study.                    Blood Adv. 2025; 9: 3865-3877.","DOI":"10.1182\/bloodadvances.2024014903"},{"key":"16","doi-asserted-by":"crossref","unstructured":"16 Brooks                            TR,                                Zabor                            EC,                                Bedelu                            Y                    <i>et al.<\/i> Real-world outcomes of patients with aggressive B-cell                    lymphoma treated with epcoritamab or glofitamab. Blood. 2025; 146:                    2177-2188.","DOI":"10.1182\/blood.2025029117"},{"key":"17","doi-asserted-by":"crossref","unstructured":"17 Abramson                            JS,                                Ku                            M,                                Hertzberg                            M                    <i>et al.<\/i> Glofitamab plus gemcitabine and oxaliplatin (GemOx)                    versus rituximab-GemOx for relapsed or refractory diffuse large B-cell lymphoma                    (STARGLO): a global phase 3, randomised, open-label trial. Lancet. 2024; 404:                    1940-1954.","DOI":"10.1016\/S0140-6736(24)01774-4"},{"key":"18","doi-asserted-by":"crossref","unstructured":"18 Brody                            JD,                                J\u00f8rgensen                            J,                                Belada                            D                    <i>et al.<\/i> Epcoritamab plus GemOx in transplant-ineligible                    relapsed\/refractory DLBCL: results from the EPCORE NHL-2 trial. Blood. 2025;                    145: 1621-1631.","DOI":"10.1182\/blood.2024026830"},{"key":"19","doi-asserted-by":"crossref","unstructured":"19 Budde                            LE,                                Olszewski                            AJ,                                Assouline                            S                    <i>et al.<\/i> Mosunetuzumab with polatuzumab vedotin in relapsed or                    refractory aggressive large B cell lymphoma: a phase 1b\/2 trial. Nat Med. 2024;                    30: 229-239.","DOI":"10.1038\/s41591-023-02726-5"},{"key":"20","doi-asserted-by":"crossref","unstructured":"20 Crombie                            JL,                                Graff                            T,                                Falchi                            L                    <i>et al.<\/i> Consensus recommendations on the management of toxicity                    associated with CD3\u00d7CD20 bispecific antibody therapy. Blood. 2024; 143:                    1565-1575.","DOI":"10.1182\/blood.2023022432"},{"key":"21","doi-asserted-by":"crossref","unstructured":"21 van                                der Horst                            HJ, de                                Jonge                            AV,                                Hiemstra                            IH                    <i>et al.<\/i> Epcoritamab induces potent anti-tumor activity against                    malignant B-cells from patients with DLBCL, FL and MCL, irrespective of prior                    CD20 monoclonal antibody treatment. Blood Cancer J. 2021; 11:                    38.","DOI":"10.1038\/s41408-021-00430-6"},{"key":"22","doi-asserted-by":"crossref","unstructured":"22 Chong                            EA,                                Penuel                            E,                                Napier                            EB                    <i>et al.<\/i> Impact of prior CAR T-cell therapy on mosunetuzumab                    efficacy in patients with relapsed or refractory B-cell lymphomas. Blood Adv.                    2025; 9: 696-703.","DOI":"10.1182\/bloodadvances.2024013640"},{"key":"23","doi-asserted-by":"crossref","unstructured":"23 Crochet                            G,                                Iacoboni                            G,                                Couturier                            A                    <i>et al.<\/i> Efficacy of CAR T-cell therapy is not impaired by                    previous bispecific antibody treatment in large B-cell lymphoma. Blood. 2024;                    144: 334-338.","DOI":"10.1182\/blood.2024024526"},{"key":"24","doi-asserted-by":"crossref","unstructured":"24 Shumilov                            E,                                Scholz                            JK,                                Seib                            M                    <i>et al.<\/i> Outcomes of bispecific antibody therapy after CAR T-cell                    failure in relapsed\/refractory large B-cell lymphoma. Blood Adv. 2025; 9:                    3955-3966.","DOI":"10.1182\/bloodadvances.2024015719"},{"key":"25","doi-asserted-by":"crossref","unstructured":"25 Br\u00f6ske                            AE,                                Korfi                            K,                                Belousov                            A                    <i>et al.<\/i> Pharmacodynamics and molecular correlates of response to                    glofitamab in relapsed\/refractory non-Hodgkin lymphoma. Blood Adv. 2022; 6:                    1025-1037.","DOI":"10.1182\/bloodadvances.2021005954"},{"key":"26","doi-asserted-by":"crossref","unstructured":"26 Iacoboni                            G,                                S\u00e1nchez-Salinas                            MA,                                Rejeski                            K                    <i>et al.<\/i> Efficacy and safety of bendamustine-containing bridging                    therapy in R\/R LBCL patients receiving CD19 CAR T-cells. HemaSphere. 2024; 8:                        e86.","DOI":"10.1002\/hem3.86"},{"key":"27","doi-asserted-by":"crossref","unstructured":"27 Schuster                            SJ,                                Huw                            LY,                                Bolen                            CR                    <i>et al.<\/i> Loss of CD20 expression as a mechanism of resistance to                    mosunetuzumab in relapsed\/refractory B-cell lymphomas. Blood. 2024; 143:                    822-832.","DOI":"10.1182\/blood.2023022348"},{"key":"28","doi-asserted-by":"crossref","unstructured":"28 Bray                            JS,                                Thomas                            GR,                                Smith                            VM                    <i>et al.<\/i> In vitro comparison of CD20xCD3 bispecific antibodies                    against diffuse large B-cell lymphoma (DLBCL) cell lines with different levels                    of expression of CD20. Br J Haematol. 2025; 206: 1350-1354.","DOI":"10.1111\/bjh.20033"},{"key":"29","doi-asserted-by":"crossref","unstructured":"29 Brouwer-Visser                            J,                                Fiaschi                            N,                                Deering                            RP                    <i>et al.<\/i> Molecular assessment of intratumoral immune cell subsets                    and potential mechanisms of resistance to odronextamab, a CD20\u00d7CD3 bispecific                    antibody, in patients with relapsed\/refractory B-cell non-Hodgkin lymphoma. J                    Immunother Cancer. 2024; 12:                    e008338.","DOI":"10.1136\/jitc-2023-008338"},{"key":"30","doi-asserted-by":"crossref","unstructured":"30 Falchi                            L,                                Rahman                            J,                                Melendez                            L                    <i>et al.<\/i> Intratumoral T-cell composition predicts                    epcoritamab-based treatment efficacy in B-cell non-Hodgkin lymphomas. medRxiv.                    2024 [Preprint].","DOI":"10.1101\/2024.07.02.24309792"},{"key":"31","doi-asserted-by":"crossref","unstructured":"31 Duell                            J,                                Leipold                            AM,                                Appenzeller                            S                    <i>et al.<\/i> Sequential antigen loss and branching evolution in                    lymphoma after CD19- and CD20-targeted T-cell-redirecting therapy. Blood. 2024;                    143: 685-696.","DOI":"10.1182\/blood.2023021672"},{"key":"32","doi-asserted-by":"crossref","unstructured":"32 Kawasaki                            N,                                Nishito                            Y,                                Yoshimura                            Y,                                Yoshiura                            S. The molecular                    rationale for the combination of polatuzumab vedotin plus rituximab in diffuse                    large B-cell lymphoma. Br J Haematol. 2022; 199: 245-255.","DOI":"10.1111\/bjh.18341"},{"key":"33","doi-asserted-by":"crossref","unstructured":"33 de                                Jonge                            AV,                                Csik\u00f3s                            T,                                Eken                            M                    <i>et al.<\/i> Delineating MYC-mediated escape mechanisms from                    conventional and T cell-redirecting therapeutic antibodies. Int J Mol Sci. 2024;                    25: 12094.","DOI":"10.3390\/ijms252212094"},{"key":"34","doi-asserted-by":"crossref","unstructured":"34 Tumuluru                            S,                                Godfrey                            JK,                                Cooper                            A                    <i>et al.<\/i> Integrative genomic analysis of DLBCL identifies immune                    environments associated with bispecific antibody response. Blood. 2025; 145:                    2460-2472.","DOI":"10.1182\/blood.2024025355"},{"key":"35","doi-asserted-by":"crossref","unstructured":"35 Wright                            GW,                                Huang                            DW,                                Phelan                            JD                    <i>et al.<\/i> A probabilistic classification tool for genetic subtypes                    of diffuse large B cell lymphoma with therapeutic implications. Cancer Cell.                    2020; 37: 551-568.e14.","DOI":"10.1016\/j.ccell.2020.03.015"},{"key":"36","doi-asserted-by":"crossref","unstructured":"36 Raj                            SS,                                Fei                            T,                                Fried                            S                    <i>et al.<\/i> An inflammatory biomarker signature of response to CAR-T                    cell therapy in non-Hodgkin lymphoma. Nat Med. 2025; 31:                    1183-1194.","DOI":"10.1038\/s41591-025-03532-x"},{"key":"37","doi-asserted-by":"crossref","unstructured":"37 Rejeski                            K,                                Perez                            A,                                Sesques                            P                    <i>et al.<\/i> CAR-HEMATOTOX: a model for CAR T-cell-related                    hematologic toxicity in relapsed\/refractory large B-cell lymphoma. Blood. 2021;                    138: 2499-2513.","DOI":"10.1182\/blood.2020010543"}],"container-title":["Journal of Clinical and Experimental Hematopathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/jslrt\/65\/4\/65_25055\/_pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,27]],"date-time":"2025-12-27T04:41:55Z","timestamp":1766810515000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/jslrt\/65\/4\/65_25055\/_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025]]},"references-count":37,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2025]]}},"URL":"https:\/\/doi.org\/10.3960\/jslrt.25055","relation":{},"ISSN":["1346-4280","1880-9952"],"issn-type":[{"value":"1346-4280","type":"print"},{"value":"1880-9952","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025]]},"article-number":"25055"}}