{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,14]],"date-time":"2025-11-14T17:12:09Z","timestamp":1763140329423},"reference-count":20,"publisher":"Japanese Society for Lymphoreticular Tissue Research","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Clin Exp Hematopathol","JCEH"],"published-print":{"date-parts":[[2007]]},"DOI":"10.3960\/jslrt.47.15","type":"journal-article","created":{"date-parts":[[2008,8,5]],"date-time":"2008-08-05T05:51:33Z","timestamp":1217915493000},"page":"15-18","source":"Crossref","is-referenced-by-count":23,"title":["Frequent DNA Methylation but not Mutation of the ID4 Gene in Malignant Lymphoma"],"prefix":"10.3960","volume":"47","author":[{"given":"Kazumi","family":"Hagiwara","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hirokazu","family":"Nagai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yinghua","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Haruhiko","family":"Ohashi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tomomitsu","family":"Hotta andHidehiko Saito","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2349","reference":[{"key":"1","doi-asserted-by":"crossref","unstructured":"1 Lossos IS : Molecular pathogenesis of diffuse large B-cell lymphoma. J Clin Oncol 23 : 6351-6357, 2005","DOI":"10.1200\/JCO.2005.05.012"},{"key":"2","doi-asserted-by":"crossref","unstructured":"2 de Jong D : Molecular pathogenesis of follicular lymphoma : A cross talk of genetic and immunologic factors. J Clin Oncol 23 : 6358-6363, 2005","DOI":"10.1200\/JCO.2005.26.856"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1038\/350512a0"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1126\/science.3874430"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.90.11.5262"},{"key":"6","doi-asserted-by":"crossref","unstructured":"6 Ichikawa A, Kinoshita T, Watanabe T, Kato H, Nagai H, Tsushita K, Saito H, Hotta T : Mutations of the p53 gene as a prognostic factor in aggressive B-cell lymphoma. N Eng J Med 337 : 529-534, 1997","DOI":"10.1056\/NEJM199708213370804"},{"issue":"1","key":"7","doi-asserted-by":"crossref","first-page":"11","DOI":"10.3960\/jslrt.42.11","volume":"42","author":"NAGAI H","year":"2002","ISSN":"http:\/\/id.crossref.org\/issn\/1346-4280","issn-type":"print"},{"key":"8","doi-asserted-by":"crossref","unstructured":"8 Jones PA, Baylin SB : The fundamental role of epigenetic events in cancer. Nat Rev Genet 3 : 415-428, 2002","DOI":"10.1038\/nrg816"},{"key":"9","doi-asserted-by":"crossref","unstructured":"9 Li Y, Nagai H, Ohno T, Yuge M, Hatano S, Ito E, Mori N, Saito H, Kinoshita T : Aberrant DNA methylation of p57<SUP>KIP2<\/SUP> gene in the promoter region in lymphoid malignancies of B-cell phenotype. Blood 100 : 2572-2577, 2002","DOI":"10.1182\/blood-2001-11-0026"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1038\/ng1521"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.1128\/MCB.20.2.429-440.2000"},{"key":"12","doi-asserted-by":"crossref","unstructured":"12 Chan AS, Tsui WY, Chen X, Chu KM, Chan TL, Chan AS, Li R, So S, Yuen ST, Leung SY : Downregulation of ID4 by promoter hypermethylation in gastric adenocarcinoma. Oncogene 22 : 6946-6953, 2003","DOI":"10.1038\/sj.onc.1206799"},{"key":"13","doi-asserted-by":"crossref","unstructured":"13 Umetani N, Takeuchi H, Fujimoto A, Shinozaki M, Bilchik AJ, Hoon DS : Epigenetic inactivation of ID4 in colorectal carcinomas correlates with poor differentiation and unfavorable prognosis. Clin Cancer Res 10 : 7475-7483, 2004","DOI":"10.1158\/1078-0432.CCR-04-0689"},{"key":"14","doi-asserted-by":"crossref","unstructured":"14 Umetani N, Mori T, Koyanagi K, Shinozaki M, Kim J, Giuliano AE, Hoon DS : Aberrant hypermethylation of ID4 gene promoter region increases risk of lymph node metastasis in T1 breast cancer. Oncogene 24 : 4721-4727, 2005","DOI":"10.1038\/sj.onc.1208538"},{"key":"15","doi-asserted-by":"publisher","DOI":"10.1093\/dnares\/5.5.309"},{"key":"16","doi-asserted-by":"crossref","unstructured":"16 Nagai H, Kinoshita T, Suzuki H, Hatano S, Murate T, Saito H : Identification and mapping of novel tumor suppressor loci on 6p in diffuse large B-cell non-Hodgkin's lymphoma. Genes Chromosomes Cancer 25 : 277-283, 1999","DOI":"10.1002\/(SICI)1098-2264(199907)25:3<277::AID-GCC10>3.0.CO;2-L"},{"key":"17","doi-asserted-by":"crossref","unstructured":"17 Esteller M, Herman JG : Cancer as an epigenetic disease : DNA methylation and chromatin alterations in human tumors. J Pathol 196 : 1-7, 2002","DOI":"10.1002\/path.1024"},{"key":"18","doi-asserted-by":"crossref","unstructured":"18 Herman JG, Baylin SB : Gene silencing in cancer in association with promoter hypermethylation. N Engl J Med 349 : 2042-2054, 2003","DOI":"10.1056\/NEJMra023075"},{"key":"19","doi-asserted-by":"crossref","unstructured":"19 Baylin SB, Esteller M, Rountree MR, Bachman KE, Schuebel K, Herman JG : Aberrant patterns of DNA methylation, chromatin formation and gene expression in cancer. Hum Mol Genet 10 : 687-692, 2001","DOI":"10.1093\/hmg\/10.7.687"},{"key":"20","doi-asserted-by":"crossref","unstructured":"20 Baur AS, Shaw P, Burri N, Delacretaz F, Bosman FT, Chaubert P : Frequent methylation silencing of p15<SUP>INK4b<\/SUP> (MTS2) and p16<SUP>INK4a<\/SUP> (MTS1) in B-cell and T-cell lymphomas. Blood 94 : 1773-1781, 1999","DOI":"10.1182\/blood.V94.5.1773"}],"container-title":["Journal of Clinical and Experimental Hematopathology"],"original-title":[],"language":"en","deposited":{"date-parts":[[2021,5,20]],"date-time":"2021-05-20T19:45:32Z","timestamp":1621539932000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.jstage.jst.go.jp\/article\/jslrt\/47\/1\/47_1_15\/_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007]]},"references-count":20,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2007]]}},"URL":"https:\/\/doi.org\/10.3960\/jslrt.47.15","relation":{},"ISSN":["1880-9952","1346-4280"],"issn-type":[{"value":"1880-9952","type":"electronic"},{"value":"1346-4280","type":"print"}],"subject":[],"published":{"date-parts":[[2007]]}}}