{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,20]],"date-time":"2026-01-20T01:27:44Z","timestamp":1768872464778,"version":"3.49.0"},"reference-count":30,"publisher":"Japanese Society for Lymphoreticular Tissue Research","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Clin Exp Hematopathol","JCEH"],"published-print":{"date-parts":[[2013]]},"DOI":"10.3960\/jslrt.53.87","type":"journal-article","created":{"date-parts":[[2013,6,20]],"date-time":"2013-06-20T23:26:52Z","timestamp":1371770812000},"page":"87-93","source":"Crossref","is-referenced-by-count":64,"title":["Atypical Hyaline Vascular-Type Castleman's Disease With Thrombocytopenia, Anasarca, Fever, and Systemic Lymphadenopathy"],"prefix":"10.3960","volume":"53","author":[{"given":"Noriko","family":"Iwaki","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yasuharu","family":"Sato","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katsuyoshi","family":"Takata","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eisei","family":"Kondo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kyotaro","family":"Ohno","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mai","family":"Takeuchi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yorihisa","family":"Orita","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shinji","family":"Nakao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tadashi","family":"Yoshino","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2349","reference":[{"key":"1","doi-asserted-by":"crossref","unstructured":"1 Castleman B, Iverson L, Menendez VP: Localized mediastinal lymphnode hyperplasia resembling thymoma. Cancer 9:822-830, 1956","DOI":"10.1002\/1097-0142(195607\/08)9:4<822::AID-CNCR2820090430>3.0.CO;2-4"},{"key":"2","doi-asserted-by":"crossref","unstructured":"2 Frizzera G, Peterson BA, Bayrd ED, Goldman A: A systemic lymphoproliferative disorder with morphologic features of Castleman's disease : clinical findings and clinicopathologic correlations in 15 patients. J Clin Oncol 3:1202-1216, 1985","DOI":"10.1200\/JCO.1985.3.9.1202"},{"key":"3","unstructured":"3 Frizzera G: Castleman's disease and related disorders. Semin Diagn Pathol 5:346-364, 1988"},{"key":"4","doi-asserted-by":"crossref","unstructured":"4 Keller AR, Hochholzer L, Castleman B: Hyaline-vascular and plasma-cell types of giant lymph node hyperplasia of the mediastinum and other locations. Cancer 29:670-683, 1972","DOI":"10.1002\/1097-0142(197203)29:3<670::AID-CNCR2820290321>3.0.CO;2-#"},{"key":"5","unstructured":"5 Kojima M, Nakamura S, Itoh H, Yoshida K, Asano S, <I>et al<\/I>.: Systemic lupus erythematosus (SLE) lymphadenopathy presenting with histopathologic features of Castleman' disease : a clinicopathologic study of five cases. Pathol Res Pract 193:565-571, 1997"},{"key":"6","doi-asserted-by":"crossref","unstructured":"6 Soulier J, Grollet L, Oksenhendler E, Cacoub P, Cazals-Hatem D, <I>et al<\/I>.: Kaposi's sarcoma-associated herpesvirus-like DNA sequences in multicentric Castleman's disease. Blood 86:1276-1280, 1995","DOI":"10.1182\/blood.V86.4.1276.bloodjournal8641276"},{"key":"7","doi-asserted-by":"crossref","unstructured":"7 Chadburn A, Cesarman E, Nador RG, Liu YF, Knowles DM: Kaposi's sarcoma-associated herpesvirus sequences in benign lymphoid proliferations not associated with human immunodeficiency virus. Cancer 80:788-797, 1997","DOI":"10.1002\/(SICI)1097-0142(19970815)80:4<788::AID-CNCR18>3.0.CO;2-P"},{"key":"8","unstructured":"8 Gessain A: Human herpesvirus 8 and associated diseases : Kaposi's sarcoma, body cavity based lymphoma and multicentric Castleman disease : clinical and molecular epidemiology. Bull Acad Natl Med 181:1023-1034, 1997 (in <I>French<\/I>)"},{"key":"9","doi-asserted-by":"crossref","unstructured":"9 Suda T, Katano H, Delsol G, Kakiuchi C, Nakamura T, <I>et al<\/I>.: HHV-8 infection status of AIDS-unrelated and AIDS-associated multicentric Castleman's disease. Pathol Int 51:671-679, 2001","DOI":"10.1046\/j.1440-1827.2001.01266.x"},{"key":"10","unstructured":"10 Kojima M, Nakamura N, Tsukamoto N, Otuski Y, Shimizu K, <I>et al<\/I>.: Clinical implications of idiopathic multicentric Castleman disease among Japanese : A report of case. Int J Surg Pathol 16:391-398, 2008"},{"key":"11","unstructured":"11 Takai K, Nikkuni K, Shibuya H, Hashidate H: Thrombocytopenia with mild bone marrow fibrosis accompanied by fever, pleural effusion, ascites and hepatosplenomegaly. Rinsho Ketsueki 51:320-325, 2010 (_m1696e <I>Japanese<\/I>)"},{"key":"12","doi-asserted-by":"crossref","unstructured":"12 Yoshizaki K, Matsuda T, Nishimoto N, Kuritani T, Taeho L, <I>et al<\/I>.: Pathogenic significance of interleukin-6 (IL-6\/BSF-2) in Castleman's disease. Blood 74:1360-1367, 1989","DOI":"10.1182\/blood.V74.4.1360.bloodjournal7441360"},{"key":"13","doi-asserted-by":"crossref","unstructured":"13 Luppi M, Barozzi P, Maiorana A, Artusi T, Trovato R, <I>et al<\/I>.: Human herpesvirus-8 DNA sequences in human immunodeficiency virus-negative angioimmunoblastic lymphadenopathy and benign lymphadenopathy with giant germinal center hyperplasia and increased vascularity. Blood 87:3903-3909, 1996","DOI":"10.1182\/blood.V87.9.3903.bloodjournal8793903"},{"key":"14","doi-asserted-by":"crossref","unstructured":"14 Aoki Y, Jaffe ES, Chang Y, Jones K, Teruya-Feldstein J, <I>et al<\/I>.: Angiogenesis and hematopoiesis induced by Kaposi's sarcoma-associated herpesvirus-encoded interleukin-6. Blood 93:4034-4043, 1999","DOI":"10.1182\/blood.V93.12.4034"},{"key":"15","doi-asserted-by":"crossref","unstructured":"15 Ishibashi T, Kimura H, Shikama Y, Uchida T, Kariyone S, <I>et al<\/I>.: Interleukin-6 is a potent thrombopoietic factor <I>in vivo<\/I> in mice. Blood 74:1241-1244, 1989","DOI":"10.1182\/blood.V74.4.1241.bloodjournal7441241"},{"key":"16","doi-asserted-by":"crossref","unstructured":"16 Tomer A: Human marrow megakaryocyte differentiation : multiparameter correlative analysis identifies von Willebrand factor as a sensitive and distinctive marker for early (2N and 4N) megakaryocytes. Blood 104:2722-2727, 2004","DOI":"10.1182\/blood-2004-02-0769"},{"key":"17","doi-asserted-by":"crossref","unstructured":"17 Cohen T, Nahari D, Cerem LW, Neufeld G, Levi BZ: Interleukin 6 induces the expression of vascular endothelial growth factor. J Biol Chem 271:736-741, 1996","DOI":"10.1074\/jbc.271.2.736"},{"key":"18","doi-asserted-by":"crossref","unstructured":"18 Nishi J, Arimura K, Utsunomiya A, Yonezawa S, Kawakami K, <I>et al<\/I>.: Expression of vascular endothelial growth factor in sera and lymph nodes of the plasma cell type of Castleman's disease. Br J Haematol 104:482-485, 1999","DOI":"10.1046\/j.1365-2141.1999.01208.x"},{"key":"19","doi-asserted-by":"crossref","unstructured":"19 Hirohata S, Miyamoto T: Elevated levels of interleukin-6 in cerebrospinal fluid from patients with systemic lupus erythematosus and central nervous system involvement. Arthritis Rheum 33:644-649, 1990","DOI":"10.1002\/art.1780330506"},{"key":"20","doi-asserted-by":"crossref","unstructured":"20 Shikama N, Terano T, Hirai A: A case of rheumatoid pericarditis with high concentrations of interleukin-6 in pericardial fluid. Heart 83:711-712, 2000","DOI":"10.1136\/heart.83.6.711"},{"key":"21","doi-asserted-by":"crossref","unstructured":"21 Webb NJ, Bottomley MJ, Watson CJ, Brenchley PE: Vascular endothelial growth factor (VEGF) is released from platelets during blood clotting : implications for measurement of circulating VEGF levels in clinical disease. Clin Sci (Lond) 94:395-404, 1998","DOI":"10.1042\/cs0940395"},{"key":"22","doi-asserted-by":"crossref","unstructured":"22 Lanfrancone L, Boraschi D, Ghiara P, Falini B, Grignani F, <I>et al<\/I>.: Human peritoneal mesothelial cells produce many cytokines (granulocyte colony-stimulating factor [CSF], granulocyte-monocyte-CSF, macrophage-CSF, interleukin-1 [IL-1], and IL-6) and are activated and stimulated to grow by IL-1. Blood 80:2835-2842, 1992","DOI":"10.1182\/blood.V80.11.2835.2835"},{"key":"23","doi-asserted-by":"crossref","unstructured":"23 Tanaka T, Kishimoto T: Targeting interleukin-6 : all the way to treat autoimmune and inflammatory diseases. Int J Biol Sci 8:1227-1236, 2012","DOI":"10.7150\/ijbs.4666"},{"key":"24","unstructured":"24 Ilonidis G, Parapanisiou E, Anogeianaki A, Giavazis I, Theofilogiannakos EK, <I>et al<\/I>.: Interleukin-1-&beta; (IL-1&beta;), interleukin 6 (IL-6) and tumor necrosis factor (TNF) in plasma and pleural fluid of pneumonia, lung cancer and tuberculous pleuritis. J Biol Regul Homeost Agents 20:41-46, 2006"},{"key":"25","doi-asserted-by":"crossref","unstructured":"25 McLaren J, Prentice A, Charnock-Jones DS, Millican SA, M&uuml;ller KH, <I>et al<\/I>.: Vascular endothelial growth factor is produced by peritoneal fluid macrophages in endometriosis and is regulated by ovarian steroids. J Clin Invest 98:482-489, 1996","DOI":"10.1172\/JCI118815"},{"key":"26","unstructured":"26 Ito A, Hirota S, Mizuno H, Kawasaki Y, Takemura T, <I>et al<\/I>.: Expression of vascular permeability factor (VPF\/VEGF) messenger RNA by plasma cells : possible involvement in the development of edema in chronic inflammation. Pathol Int 45:715-720, 1995"},{"key":"27","doi-asserted-by":"crossref","unstructured":"27 Bower M : How I treat HIV-associated multicentric Castleman disease. Blood 116 : 4415-4421, 2010","DOI":"10.1182\/blood-2010-07-290213"},{"key":"28","doi-asserted-by":"crossref","unstructured":"28 Ide M, Kawachi Y, Izumi Y, Kasagi K, Ogino T: Long-term remission in HIV-negative patients with multicentric Castleman's disease using rituximab. Eur J Haematol 76:119-123, 2006","DOI":"10.1111\/j.1600-0609.2005.00570.x"},{"key":"29","doi-asserted-by":"crossref","unstructured":"29 Ocio EM, Sanchez-Guijo FM, Diez-Campelo M, Castilla C, Blanco OJ, <I>et al<\/I>.: Efficacy of rituximab in an aggressive form of multicentric Castleman disease associated with immune phenomena. Am J Hematol 78:302-305, 2005","DOI":"10.1002\/ajh.20283"},{"key":"30","doi-asserted-by":"crossref","unstructured":"30 Nishimoto N, Kanakura Y, Aozasa K, Johkoh T, Nakamura M, <I>et al<\/I>.: Humanized anti-interleukin-6 receptor antibody treatment of multicentric Castleman disease. Blood 106:2627-2632, 2005","DOI":"10.1182\/blood-2004-12-4602"}],"container-title":["Journal of Clinical and Experimental Hematopathology"],"original-title":[],"language":"en","deposited":{"date-parts":[[2021,5,20]],"date-time":"2021-05-20T19:46:39Z","timestamp":1621539999000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/jslrt\/53\/1\/53_87\/_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013]]},"references-count":30,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2013]]}},"URL":"https:\/\/doi.org\/10.3960\/jslrt.53.87","relation":{},"ISSN":["1346-4280","1880-9952"],"issn-type":[{"value":"1346-4280","type":"print"},{"value":"1880-9952","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013]]}}}